Publications by authors named "Jonathan Mullins"

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Mechanism-based inactivation of human aldehyde oxidase by erlotinib: Mechanistic insights from structural analogs and molecular docking.
Jia Rong Kweh, Nicholas Kai Ming Ng, Le Min Ngoh, Cynthia Jing Yan Li, Bao Jie Tan, Jonathan G L Mullins

Mol Pharmacol· December 2025

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Computational structural studies of SGLT2-related polypharmacy.
Aled Lloyd, Karl Austin-Muttitt, Jonathan G L Mullins

PLoS One· October 2025

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In silico drug repurposing at the cytoplasmic surface of human aquaporin 1.
Aled R Lloyd, Karl Austin-Muttitt, Jonathan G L Mullins

PLoS One· January 2025

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Hunger signalling in the olfactory bulb primes exploration, food-seeking and peripheral metabolism.
Romana Stark, Harry Dempsey, Elizabeth Kleeman, Martina Sassi, Sherri Osborne-Lawrence, Jonathan Mullins

Mol Metab· November 2024

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PDE4B Missense Variant Increases Susceptibility to Post-traumatic Stress Disorder-Relevant Phenotypes in Mice.
Tatiana V Lipina, Shupeng Li, Ekaterina S Petrova, Tamara G Amstislavskaya, Ryan T Cameron, Jonathan G L Mullins

J Neurosci· October 2024

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PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies.
Ahmed H Al-Amri, Paul Armstrong, Mascia Amici, Clemence Ligneul, James Rouse, Jonathan G L Mullins

Biol Psychiatry· August 2022

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Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity.
David C Lamb, Jared V Goldstone, Bin Zhao, Li Lei, Jonathan G L Mullins

Biomolecules· August 2022

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Drug repurposing in silico screening platforms.
Jonathan G L Mullins

Biochem Soc Trans· April 2022

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Bisphosphonate inhibitors of squalene synthase protect cells against cholesterol-dependent cytolysins.
Mateusz Pospiech, Siân E Owens, David J Miller, Karl Austin-Muttitt, Jonathan G L Mullins

FASEB J· June 2021

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Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.
Jonas Abdel-Khalik, Thomas Hearn, Alison L Dickson, Peter J Crick, Eylan Yutuc, Jonathan G L Mullins

J Steroid Biochem Mol Biol· February 2021

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In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate.
Wee Kiat Tan, Alyssa Rui Yi Tan, Punitha Sivanandam, Ernest Jing Hui Goh, Ze Ping Yap, Jonathan G L Mullins

J Pharmacol Exp Ther· August 2020

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In Vitro and In Silico Analyses of the Inhibition of Human Aldehyde Oxidase by Bazedoxifene, Lasofoxifene, and Structural Analogues.
Shiyan Chen, Karl Austin-Muttitt, Linghua Harris Zhang, Jonathan G L Mullins, Aik Jiang Lau

J Pharmacol Exp Ther· October 2019

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Clinical and Functional Characterization of the Recurrent TUBA1A p.(Arg2His) Mutation.
Jennifer F Gardner, Thomas D Cushion, Georgios Niotakis, Heather E Olson, P Ellen Grant, Jonathan G L Mullins

Brain Sci· August 2018

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De novo mutations in GRIN1 cause extensive bilateral polymicrogyria.
Andrew E Fry, Katherine A Fawcett, Nathanel Zelnik, Hongjie Yuan, Belinda A N Thompson, Jonathan G L Mullins

Brain· March 2018

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Structure-Related Differences between Cytochrome Oxidase I Proteins in a Stable Heteroplasmic Mitochondrial System.
David O F Skibinski, Fabrizio Ghiselli, Angel P Diz, Liliana Milani, Jonathan G L Mullins

Genome Biol Evol· December 2017

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Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition.
Alexander McGirr, Tatiana V Lipina, Ho-Suk Mun, John Georgiou, Ahmed H Al-Amri, Jonathan Gl Mullins

Neuropsychopharmacology· April 2017

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Demethylase Inhibitor Fungicide Resistance in Pyrenophora teres f. sp. teres Associated with Target Site Modification and Inducible Overexpression of Cyp51.
Wesley J Mair, Weiwei Deng, Jonathan G L Mullins, Samuel West, Penghao Wang

Front Microbiol· September 2016

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Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition.
Alexander McGirr, Tatiana V Lipina, Ho-Suk Mun, John Georgiou, Ahmed H Al-Amri, Jonathan G L Mullins

Neuropsychopharmacology· March 2016

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RfiA, a novel PAP2 domain-containing polytopic membrane protein that confers resistance to the FtsZ inhibitor PC190723.
Ximing Chen, Binglin Zhang, Jianxi Xiao, Furong Ju, Shuyan Li, Jonathan Gl Mullins

Future Microbiol· January 2016

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Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes.
Renske Oegema, Thomas D Cushion, Ian G Phelps, Seo-Kyung Chung, Jennifer C Dempsey, Jonathan G L Mullins

Hum Mol Genet· September 2015

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Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase.
Claire L Price, Andrew G S Warrilow, Josie E Parker, Jonathan G L Mullins, W David Nes

Appl Environ Microbiol· May 2015

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Resistance to antifungals that target CYP51.
Josie E Parker, Andrew G S Warrilow, Claire L Price, Jonathan G L Mullins, Diane E Kelly

J Chem Biol· October 2014

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A novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes.
Ann J Johnston, Jing-Qiong Kang, Wangzhen Shen, William O Pickrell, Thomas D Cushion, Jonathan G L Mullins

Neurobiol Dis· April 2014

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De novo mutations in the beta-tubulin gene TUBB2A cause simplified gyral patterning and infantile-onset epilepsy.
Thomas D Cushion, Alex R Paciorkowski, Daniela T Pilz, Jonathan G L Mullins, Laurie E Seltzer

Am J Hum Genet· April 2014

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New hyperekplexia mutations provide insight into glycine receptor assembly, trafficking, and activation mechanisms.
Anna Bode, Sian-Elin Wood, Jonathan G L Mullins, Angelo Keramidas, Thomas D Cushion

J Biol Chem· November 2013

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