Publications by authors named "Jonathan P Staley"

Claim this Profile
B
Brr2p-mediated unwinding of U4/U6 is promoted by a mutually exclusive intra-molecular stem loop in U4 and involves destabilization of the 5' stem-loop of U4.
Klaus H Nielsen, Amartya Das, Jonathan P Staley

bioRxiv· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Elevated levels of intracellular RNA lariats suppress the antiviral response.
Chaorui Duan, Luke Buerer, Cory Bowers, Allison J Taggart, Mara H O'Brien, Jonathan P Staley

bioRxiv· December 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Global impact of unproductive splicing on human gene expression.
Benjamin Fair, Carlos F Buen Abad Najar, Junxing Zhao, Stephanie Lozano, Austin Reilly, Jonathan P Staley

Nat Genet· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Luke Buerer, Nathaniel E Clark, Anastasia Welch, Chaorui Duan, Allison J Taggart, Jonathan P Staley

Nat Commun· May 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Global impact of aberrant splicing on human gene expression levels.
Benjamin Fair, Carlos Buen Abad Najar, Junxing Zhao, Stephanie Lozano, Austin Reilly, Jonathan P Staley

bioRxiv· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Luke Buerer, Nathaniel E Clark, Anastasia Welch, Chaorui Duan, Allison J Taggart, Jonathan P Staley

Res Sq· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing.
Yi Zeng, Benjamin J Fair, Huilin Zeng, Aiswarya Krishnamohan, Yichen Hou, Jonathan P Staley

Mol Cell· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6.
Rebecca Toroney, Klaus H Nielsen, Jonathan P Staley

Genes Dev· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.
Yangzi He, Jonathan P Staley, Gregers Rom Andersen, Klaus H Nielsen

RNA· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA.
Sharon Soucek, Yi Zeng, Deepti L Bellur, Megan Bergkessel, Kevin J Morris, Jonathan P Staley

Mol Cell Biol· November 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Yaming Shao, Hao Huang, Daoming Qin, Nan-Sheng Li, Akiko Koide, Jonathan P Staley

J Mol Biol· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reverse transcriptases lend a hand in splicing catalysis.
Joseph A Piccirilli, Jonathan P Staley

Nat Struct Mol Biol· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.
Diana Rose E Ranoa, Akash D Parekh, Sean P Pitroda, Xiaona Huang, Thomas Darga, Jonathan P Staley

Oncotarget· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sequencing of lariat termini in S. cerevisiae reveals 5' splice sites, branch points, and novel splicing events.
Daoming Qin, Lei Huang, Alissa Wlodaver, Jorge Andrade, Jonathan P Staley

RNA· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.
Daniel R Semlow, Mario R Blanco, Nils G Walter, Jonathan P Staley

Cell· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Knocking Down Snrnp200 Initiates Demorphogenesis of Rod Photoreceptors in Zebrafish.
Yuan Liu, Xue Chen, Bing Qin, Kanxing Zhao, Qingshun Zhao, Jonathan P Staley

J Ophthalmol· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evidence for a group II intron-like catalytic triplex in the spliceosome.
Sebastian M Fica, Melissa A Mefford, Joseph A Piccirilli, Jonathan P Staley

Nat Struct Mol Biol· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and incorporation of the phosphoramidite derivative of 2'-O-photocaged 3'-s-thioguanosine into oligoribonucleotides: substrate for probing the mechanism of RNA catalysis.
Nan-Sheng Li, Nicole Tuttle, Jonathan P Staley, Joseph A Piccirilli

J Org Chem· April 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome.
Alissa M Wlodaver, Jonathan P Staley

RNA· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA catalyses nuclear pre-mRNA splicing.
Sebastian M Fica, Nicole Tuttle, Thaddeus Novak, Nan-Sheng Li, Jun Lu, Jonathan P Staley

Nature· November 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Splicing fidelity: DEAD/H-box ATPases as molecular clocks.
Prakash Koodathingal, Jonathan P Staley

RNA Biol· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Matthew J Schellenberg, Tao Wu, Dustin B Ritchie, Sebastian Fica, Jonathan P Staley

Nat Struct Mol Biol· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast.
Ram Kannan, Sean Hartnett, Rodger B Voelker, J Andrew Berglund, Jonathan P Staley

Genes Dev· March 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Spliceosome activation: U4 is the path, stem I is the goal, and Prp8 is the keeper. Let's cheer for the ATPase Brr2!
Klaus H Nielsen, Jonathan P Staley

Genes Dev· November 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Staying on message: ensuring fidelity in pre-mRNA splicing.
Daniel R Semlow, Jonathan P Staley

Trends Biochem Sci· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis