Publications by authors named "Jonathan Schatz"

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Racial and Clinical Determinants of Response in 2,304 r/r BCL Treated with Anti-CD19 CAR T-Cells in Clinical Trials.
Soon Jye Kho, Sheila S Diamond, Penelope Lafeuille, Jonathan H Schatz, Francesco Maura

Blood Adv· November 2025

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Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy.
Paola Manara, Austin D Newsam, Venu Venkatarame Gowda Saralamma, Tyler Andrew Cunningham, Drew Lazenby, Jonathan H Schatz

Cancer Res· October 2025

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Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies.
Benjamin Diamond, Dhanvantri Chahar, Michael D Jain, Alexandra M Poos, Michael A Durante, Jonathan Harry Schatz

Blood Cancer Discov· September 2025

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Bispecific Antibodies in Hematologic Malignancies: Attacking the Frontline.
Toral Shastri, Asaad Trabolsi, Artavazd Arumov, Jonathan H Schatz

BioDrugs· September 2025

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RHOA Loss of Function Impairs the IFNγ Response and Promotes CD19 Antigen Escape to Drive CAR-T Resistance in Diffuse Large B-cell Lymphoma.
Austin D Newsam, Bachisio Ziccheddu, Venu Venkatarame Gowda Saralamma, Caroline A Coughlin, Yitzhar E Goretsky, Jonathan H Schatz

bioRxiv· March 2025

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Bruton's tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Caroline A Coughlin, Dhanvantri Chahar, Marianna Lekakis, Abdessamad A Youssfi, Lingxiao Li, Jonathan H Schatz

Blood Cancer J· February 2025

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Loncastuximab tesirine with rituximab in patients with relapsed or refractory follicular lymphoma: a single-centre, single-arm, phase 2 trial.
Juan Pablo Alderuccio, Alvaro J Alencar, Jonathan H Schatz, Russ A Kuker, Georgios Pongas

Lancet Haematol· January 2025

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Mutagenic impact and evolutionary influence of radiotherapy in hematologic malignancies.
Benjamin Diamond, Dhanvantri Chahar, Michael D Jain, Alexandra M Poos, Michael Durante, Jonathan H Schatz

bioRxiv· November 2024

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The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma.
Olivia B Lightfuss, Preet Kumar, Lingxiao Li, Toral Shastri, Austin D Newsam, Jonathan H Schatz

bioRxiv· October 2024

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NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy.
Paola Manara, Austin D Newsam, Venu Vg Saralamma, Marco V Russo, Alicia Bilbao Martinez, Jonathan H Schatz

bioRxiv· September 2024

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Bispecific antibodies and CAR-T cells: dueling immunotherapies for large B-cell lymphomas.
Asaad Trabolsi, Artavazd Arumov, Jonathan H Schatz

Blood Cancer J· February 2024

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Functional drivers of resistance to anti-CD19 CAR-T cell therapy in diffuse large B cell lymphoma.
Austin D Newsam, Caroline A Coughlin, Asaad Trabolsi, Jonathan H Schatz

Leuk Lymphoma· December 2023

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Efficacy of checkpoint inhibition after CAR-T failure in aggressive B-cell lymphomas: outcomes from 15 US institutions.
Ajay Major, Jovian Yu, Navika Shukla, Yan Che, Theodore G Karrison, Jonathan H Schatz

Blood Adv· August 2023

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MATRIX platform to analyze translation machinery remodeling in glioblastoma cells.
J J David Ho, Tyler A Cunningham, Jonathan R Krieger, Jonathan H Schatz, Stephen Lee

STAR Protoc· December 2022

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Whole-genome sequencing reveals complex genomic features underlying anti-CD19 CAR T-cell treatment failures in lymphoma.
Michael D Jain, Bachisio Ziccheddu, Caroline A Coughlin, Rawan Faramand, Anthony J Griswold, Jonathan H Schatz

Blood· August 2022

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A phase 2 biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas.
Alison J Moskowitz, Paola Ghione, Eric Jacobsen, Jia Ruan, Jonathan H Schatz

Blood· December 2021

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Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action.
Christopher J Zerio, Tyler A Cunningham, Allison S Tulino, Erin A Alimusa, Thomas M Buckley, Jonathan H Schatz

J Med Chem· November 2021

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Potency Meets Precision in Nano-optimized Chemotherapeutics.
Artavazd Arumov, Asaad Trabolsi, Jonathan H Schatz

Trends Biotechnol· October 2021

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Proteomics reveal cap-dependent translation inhibitors remodel the translation machinery and translatome.
J J David Ho, Tyler A Cunningham, Paola Manara, Caroline A Coughlin, Artavazd Arumov, Jonathan H Schatz

Cell Rep· October 2021

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Translational remodeling by RNA-binding proteins and noncoding RNAs.
J J David Ho, Jeffrey H S Man, Jonathan H Schatz, Philip A Marsden

Wiley Interdiscip Rev RNA· September 2021

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Molecular Dynamics Simulations Identify Tractable Lead-like Phenyl-Piperazine Scaffolds as eIF4A1 ATP-competitive Inhibitors.
Derek J Essegian, Tyler A Cunningham, Christopher J Zerio, Eli Chapman, Jonathan Schatz

ACS Omega· September 2021

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Jekyll and Hyde: Activating the Hypoxic Translational Machinery.
J J David Ho, Jonathan H Schatz, Jim Uniacke, Stephen Lee

Trends Biochem Sci· March 2021

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Optimized Doxorubicin Chemotherapy for Diffuse Large B-cell Lymphoma Exploits Nanocarrier Delivery to Transferrin Receptors.
Artavazd Arumov, Piumi Y Liyanage, Asaad Trabolsi, Evan R Roberts, Lingxiao Li, Jonathan H Schatz

Cancer Res· February 2021

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NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy.
Viraj R Sanghvi, Prathibha Mohan, Kamini Singh, Linlin Cao, Marjan Berishaj, Jonathan H Schatz

Cancers (Basel)· February 2021

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A translational program that suppresses metabolism to shield the genome.
Nathan C Balukoff, J J David Ho, Phaedra R Theodoridis, Miling Wang, Michael Bokros, Jonathan H Schatz

Nat Commun· November 2020

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