Publications by authors named "Jonathan Wren"

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Hepatocyte MLKL Drives Obesity-Driven Hepatocellular Carcinoma Progression via Mitochondrial Dysfunction Independent of Necroptosis in MASLD.
Phoebe Ohene-Marfo, Sabira Mohammed, Chao Jiang, Shylesh Bhaskaran, Constantin Georgescu, Jonathan D Wren

bioRxiv· November 2025

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Publisher Correction: Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases.
Yingjun Ding, Junxiong Chen, Songlan Liu, Jennifer M Hays, Xiaowu Gu, Jonathan D Wren

Nat Cardiovasc Res· September 2025

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Tetraspanin-enriched membrane domains regulate vascular leakage by altering membrane cholesterol accessibility to balance antagonistic GTPases.
Yingjun Ding, Junxiong Chen, Songlan Liu, Jennifer M Hays, Xiaowu Gu, Jonathan D Wren

Nat Cardiovasc Res· August 2025

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Methylation array signals are predictive of chronological age without bisulfite conversion.
Hunter L Porter, Victor A Ansere, Ram Babu Undi, Walker Hoolehan, Cory B Giles, Jonathan D Wren

Geroscience· July 2025

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A Non-canonical Role for Hepatocyte MLKL in Promoting Mitochondrial Dysfunction and Senescence in the Aging Liver.
Sabira Mohammed, Chao Jiang, Travis Pennington, Shylesh Bhaskaran, Phoebe Ohene-Marfo, Jonathan D Wren

bioRxiv· May 2025

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Spatial transcriptomics delineates potential differences in intestinal phenotypes of cardiac and classical necrotizing enterocolitis.
Kathryn Y Burge, Constantin Georgescu, Hua Zhong, Adam P Wilson, Aarthi Gunasekaran, Jonathan D Wren

iScience· April 2025

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A satellite cell-dependent epigenetic fingerprint in skeletal muscle identity genes after lifelong physical activity.
Kevin A Murach, Davis A Englund, Toby L Chambers, Cory M Dungan, Hunter L Porter, Jonathan D Wren

FASEB J· March 2025

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The toll like receptor 7 pathway and the sex bias of systemic lupus erythematosus.
R Hal Scofield, Jonathan D Wren, Valerie M Lewis

Front Immunol· March 2025

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Unacylated Ghrelin Protects Against Age-Related Loss of Muscle Mass and Contractile Dysfunction in Skeletal Muscle.
Hyunyoung Kim, Rojina Ranjit, Dennis R Claflin, Constantin Georgescu, Jonathan D Wren

Aging Cell· December 2024

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The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis.
Shylesh Bhaskaran, Katarzyna M Piekarz, Jacob Brown, Brian Yang, Sarah R Ocañas, Jonathan D Wren

Front Neurosci· November 2024

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Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium.
Dimitrios Pollalis, Gopa Kumar Gopinadhan Nair, Justin Leung, Clarisa Marie Bloemhof, Jeffrey K Bailey, Jonathan D Wren

J Extracell Biol· September 2024

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CD151 Maintains Endolysosomal Protein Quality to Inhibit Vascular Inflammation.
Junxiong Chen, Yingjun Ding, Chao Jiang, Rongmei Qu, Jonathan D Wren

Circ Res· May 2024

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Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium.
Dimitrios Pollalis, Constantin Georgescu, Jonathan D Wren, Grigor Tombulyan, Justin M Leung

bioRxiv· April 2024

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AutoGDC: A Python Package for DNA Methylation and Transcription Meta-Analyses.
Chase Alan Brown, Jonathan D Wren

bioRxiv· April 2024

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BioVDB: biological vector database for high-throughput gene expression meta-analysis.
Michał J Winnicki, Chase A Brown, Hunter L Porter, Cory B Giles, Jonathan D Wren

Front Artif Intell· March 2024

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Methylation Array Signals are Predictive of Chronological Age Without Bisulfite Conversion.
Hunter L Porter, Victor A Ansere, Ram Babu Undi, Walker Hoolehan, Cory B Giles, Jonathan D Wren

bioRxiv· December 2023

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Autoantibodies identify primary Sjögren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B.
Sherri Longobardi, Charmaine Lopez-Davis, Bhuwan Khatri, Constantin Georgescu, Cherilyn Pritchett-Frazee, Christina Lawrence, Jonathan D Wren

Ann Rheum Dis· September 2023

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Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis.
Sabira Mohammed, Nidheesh Thadathil, Phoebe Ohene-Marfo, Albert L Tran, Michael Van Der Veldt, Jonathan D Wren

Mol Cancer Res· September 2023

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An unbiased seed-based RNAi selection screen identifies small RNAs that inhibit androgen signaling and prostate cancer cell growth.
Joshua M Corbin, Constantin Georgescu, Lin Wang, Jonathan D Wren, Magdalena Bieniasz

Mol Ther Nucleic Acids· September 2023

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Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor.
Jiang Min, Shenglan Yang, Yang Cai, David R Vanderwall, Zhiping Wu, Jonathan D Wren

Cell Mol Life Sci· May 2023

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EWI2 and its relatives in Tetraspanin-enriched membrane domains regulate malignancy.
Yingjun Ding, Junxiong Chen, Shuping Li, Jonathan D Wren, Akhilesh K Bajpai

Oncogene· March 2023

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The Isolation and In Vitro Differentiation of Primary Fetal Baboon Tracheal Epithelial Cells for the Study of SARS-CoV-2 Host-Virus Interactions.
Bharathiraja Subramaniyan, Sunam Gurung, Manish Bodas, Andrew R Moore, Jason L Larabee, Jonathan D Wren

Viruses· March 2023

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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy.
Jacob L Brown, Fredrick F Peelor, Constantin Georgescu, Jonathan D Wren, Michael Kinter

Redox Biol· November 2022

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Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses.
Michelle L Joachims, Bhuwan Khatri, Chuang Li, Kandice L Tessneer, John A Ice, Jonathan D Wren

RMD Open· November 2022

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Detecting anomalous referencing patterns in PubMed papers suggestive of author-centric reference list manipulation.
Jonathan D Wren, Constantin Georgescu

Scientometrics· October 2022

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