Publications by authors named "Joo-Ri Kim-Kaneyama"

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A Novel PLCD1 Variant in Familial Trichilemmal Cysts With Leukonychia: Per-Cyst Second Hits Support a Monoallelic Two-Hit Mechanism.
Xiaofeng Lei, Teruaki Izumi, Natsuko Okuyama, Kazufumi Shirouchi, Kae Kobayashi, Joo-Ri Kim-Kaneyama

J Dermatol· October 2025

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Medium-Chain Fatty Acids Ameliorate Liver Fibrosis by Phosphorylating Hepatic Stellate Cell Forkhead Box Protein O1.
Masashi Sakaki, Joo-Ri Kim-Kaneyama, Masahito Noguchi, Aya Miyauchi, Xiao-Feng Lei

Liver Int· September 2025

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Hic-5 antisense oligonucleotide inhibits advanced hepatic fibrosis and steatosis .
Masahito Noguchi, Aya Miyauchi, Yoshiaki Masaki, Masashi Sakaki, Xiao-Feng Lei, Joo-Ri Kim-Kaneyama

JHEP Rep· November 2024

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Innate Immune System Regulated by Stimulator of Interferon Genes, a Cytosolic DNA Sensor, Regulates Endothelial Function.
Phuong Tran Pham, Oyunbileg Bavuu, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Takayuki Yamamoto

J Am Heart Assoc· November 2023

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Author Correction: Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13.
Aya Miyauchi, Masahito Noguchi, Xiao-Feng Lei, Masashi Sakaki, Momoko Kobayashi-Tanabe, Joo-Ri Kim-Kaneyama

Sci Rep· June 2023

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Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13.
Aya Miyauchi, Masahito Noguchi, Xiao-Feng Lei, Masashi Sakaki, Momoko Kobayashi-Tanabe, Joo-Ri Kim-Kaneyama

Sci Rep· May 2023

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Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking.
Takuro Miyazaki, Yoshitaka Taketomi, Takayoshi Higashi, Hirokazu Ohtaki, Takashi Takaki, Joo-Ri Kim-Kaneyama

Arterioscler Thromb Vasc Biol· February 2023

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STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases.
Phuong Tran Pham, Daiju Fukuda, Sachiko Nishimoto, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei

Eur Heart J· November 2021

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Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis.
Lin Gao, Xiao-Feng Lei, Aya Miyauchi, Masahito Noguchi, Tomokatsu Omoto, Joo-Ri Kim-Kaneyama

Sci Rep· November 2020

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Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.
Takeshi Oichi, Yuki Taniguchi, Kazuhito Soma, Yasushi Oshima, Fumiko Yano, Joo-Ri Kim-Kaneyama

Cell Mol Life Sci· December 2019

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Correction to: Adamts17 is involved in skeletogenesis through modulation of BMP‑Smad1/5/8 pathway.
Takeshi Oichi, Yuki Taniguchi, Kazuhito Soma, Yasushi Oshima, Fumiko Yano, Joo-Ri Kim-Kaneyama

Cell Mol Life Sci· December 2019

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Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5.
Aya Miyauchi, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Song Ho Chang, Taku Saito

Sci Rep· October 2019

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Light-at-night exposure affects brain development through pineal allopregnanolone-dependent mechanisms.
Shogo Haraguchi, Masaki Kamata, Takuma Tokita, Kei-Ichiro Tashiro, Miku Sato, Joo-Ri Kim-Kaneyama

Elife· September 2019

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Toll-Like Receptor 9 Plays a Pivotal Role in Angiotensin II-Induced Atherosclerosis.
Daiju Fukuda, Sachiko Nishimoto, Kunduziayi Aini, Atsushi Tanaka, Tsuyoshi Nishiguchi, Joo-Ri Kim-Kaneyama

J Am Heart Assoc· April 2019

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Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Song Ho Chang, Daisuke Mori, Hiroshi Kobayashi, Yoshifumi Mori, Hideki Nakamoto, Joo-Ri Kim-Kaneyama

Nat Commun· March 2019

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Endothelial calpain systems orchestrate myofibroblast differentiation during wound healing.
Takuro Miyazaki, Shogo Haraguchi, Joo-Ri Kim-Kaneyama, Akira Miyazaki

FASEB J· February 2019

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The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Tomokatsu Omoto, Joo-Ri Kim-Kaneyama, Xiao-Feng Lei, Akira Orimo, Koji Ohnishi

Oncogene· March 2018

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Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells.
Mitsuki Nozaki, Shogo Haraguchi, Takuro Miyazaki, Daichi Shigeta, Noriko Kano, Joo-Ri Kim-Kaneyama

Sci Rep· February 2018

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Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases.
Yasuyoshi Kigawa, Takuro Miyazaki, Xiao-Feng Lei, Joo-Ri Kim-Kaneyama, Akira Miyazaki

J Atheroscler Thromb· January 2017

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The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.
Yeha Kim, Soyeon Lim, Taejeong Ha, You-Hyang Song, Young-In Sohn, Joo-Ri Kim-Kaneyama

Elife· January 2017

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The pathophysiological role of oxidized cholesterols in epicardial fat accumulation and cardiac dysfunction: a study in swine fed a high caloric diet with an inhibitor of intestinal cholesterol absorption, ezetimibe.
Michio Shimabukuro, Chinami Okawa, Hirotsugu Yamada, Shuhei Yanagi, Etsuko Uematsu, Joo-Ri Kim-Kaneyama

J Nutr Biochem· September 2016

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Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing.
Takuro Miyazaki, Kazuo Tonami, Shoji Hata, Toshihiro Aiuchi, Koji Ohnishi, Joo-Ri Kim-Kaneyama

J Clin Invest· September 2016

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Roles of paxillin family members in adhesion and ECM degradation coupling at invadosomes.
Christos Petropoulos, Christiane Oddou, Anouk Emadali, Edwige Hiriart-Bryant, Cyril Boyault, Joo-Ri Kim-Kaneyama

J Cell Biol· June 2016

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Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance.
Sachiko Nishimoto, Daiju Fukuda, Yasutomi Higashikuni, Kimie Tanaka, Yoichiro Hirata, Joo-Ri Kim-Kaneyama

Sci Adv· March 2016

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Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice.
Xiao-Feng Lei, Wenguang Fu, Joo-Ri Kim-Kaneyama, Tomokatsu Omoto, Takuro Miyazaki

J Hepatol· January 2016

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