Publications by authors named "Jorge Chaves"

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Zanidatamab monotherapy or combined with chemotherapy in HER2-expressing gastroesophageal adenocarcinoma: a phase 1 trial.
Funda Meric-Bernstam, Sun Young Rha, Erika Hamilton, Yoon-Koo Kang, Diana L Hanna, Jorge Chaves

Nat Commun· May 2025

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Pembrolizumab Plus Binimetinib With or Without Chemotherapy for MSS/pMMR Metastatic Colorectal Cancer: Outcomes From KEYNOTE-651 Cohorts A, C, and E.
Eric X Chen, Petr Kavan, Mustapha Tehfe, Jeremy S Kortmansky, Michael B Sawyer, Jorge Chaves

Clin Colorectal Cancer· June 2024

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Pembrolizumab Plus mFOLFOX7 or FOLFIRI for Microsatellite Stable/Mismatch Repair-Proficient Metastatic Colorectal Cancer: KEYNOTE-651 Cohorts B and D.
Richard Kim, Mustapha Tehfe, Petr Kavan, Jorge Chaves, Jeremy S Kortmansky

Clin Colorectal Cancer· June 2024

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Zanidatamab, a novel bispecific antibody, for the treatment of locally advanced or metastatic HER2-expressing or HER2-amplified cancers: a phase 1, dose-escalation and expansion study.
Funda Meric-Bernstam, Muralidhar Beeram, Erika Hamilton, Do-Youn Oh, Diana L Hanna, Jorge Chaves

Lancet Oncol· December 2022

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Phase 1/2 study of intratumoral G100 (TLR4 agonist) with or without pembrolizumab in follicular lymphoma.
Ahmad S Halwani, Carlos Panizo, Iris Isufi, Alex F Herrera, Craig Y Okada, Jorge M Chaves

Leuk Lymphoma· April 2022

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Safety and Efficacy of Andecaliximab (GS-5745) Plus Gemcitabine and Nab-Paclitaxel in Patients with Advanced Pancreatic Adenocarcinoma: Results from a Phase I Study.
Johanna Bendell, Sunil Sharma, Manish R Patel, Kevin S Windsor, Zev A Wainberg, Jorge Chaves

Oncologist· November 2020

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Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results.
John C Byrd, William G Wierda, Anna Schuh, Stephen Devereux, Jorge M Chaves

Blood· April 2020

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Avelumab monotherapy as first-line or second-line treatment in patients with metastatic renal cell carcinoma: phase Ib results from the JAVELIN Solid Tumor trial.
Ulka Vaishampayan, Patrick Schöffski, Alain Ravaud, Christian Borel, Julio Peguero, Jorge Chaves

J Immunother Cancer· October 2019

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Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer: Phase 1b Results From the JAVELIN Solid Tumor Trial.
Mary L Disis, Matthew H Taylor, Karen Kelly, J Thaddeus Beck, Michael Gordon, Jorge Chaves

JAMA Oncol· March 2019

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Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastatic pancreatic ductal adenocarcinoma.
Kimmie Ng, Andrew Hendifar, Alexander Starodub, Jorge Chaves, Yingsi Yang

Invest New Drugs· February 2019

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Tucatinib Combined With Ado-Trastuzumab Emtansine in Advanced ERBB2/HER2-Positive Metastatic Breast Cancer: A Phase 1b Clinical Trial.
Virginia F Borges, Cristiano Ferrario, Nathalie Aucoin, Carla Falkson, Qamar Khan, Jorge Chaves

JAMA Oncol· September 2018

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Andecaliximab/GS-5745 Alone and Combined with mFOLFOX6 in Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Results from a Phase I Study.
Manish A Shah, Alexander Starodub, Sunil Sharma, Jordan Berlin, Manish Patel, Jorge Chaves

Clin Cancer Res· August 2018

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Tucatinib with capecitabine and trastuzumab in advanced HER2-positive metastatic breast cancer with and without brain metastases: a non-randomised, open-label, phase 1b study.
Rashmi Murthy, Virginia F Borges, Alison Conlin, Jorge Chaves, Marc Chamberlain

Lancet Oncol· July 2018

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Mass balance, pharmacokinetics, and metabolism of linsitinib in cancer patients.
Srinivasu Poondru, Jorge Chaves, Geoffrey Yuen, Barbara Parker, Elizabeth Conklin

Cancer Chemother Pharmacol· April 2016

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Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia.
John C Byrd, Bonnie Harrington, Susan O'Brien, Jeffrey A Jones, Anna Schuh, Jorge Chaves

N Engl J Med· January 2016

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A phase 1 study of ABT-806 in subjects with advanced solid tumors.
James M Cleary, David A Reardon, Nilofer Azad, Leena Gandhi, Geoffrey I Shapiro, Jorge Chaves

Invest New Drugs· June 2015

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[A need to monitor P. falciparum resistance to artesunate in Peru].
Salomón Durand, Moisés Sihuincha, Arnaldo Lachira, Jorge Chaves, César Cabezas

Rev Peru Med Exp Salud Publica· January 2014

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IGF system in cancer: from bench to clinic.
Jorge Chaves, Muhammad Wasif Saif

Anticancer Drugs· March 2011

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[A case-control study of extracorporeal versus intracorporeal anastomosis in patients subjected to right laparoscopic hemicolectomy].
Jorge Arredondo Chaves, Carlos Pastor Idoate, Jorge Baixauli Fons, Manuel Bellver Oliver, Nicolás Pedano Rodríguez

Cir Esp· January 2011

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Phosphodiesterase 4 inhibitors augment levels of glucocorticoid receptor in B cell chronic lymphocytic leukemia but not in normal circulating hematopoietic cells.
John A Meyers, Josephine Taverna, Jorge Chaves, Anthony Makkinje, Adam Lerner

Clin Cancer Res· August 2007

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Aerosolized ribavirin-induced reversible hepatotoxicity in a hematopoietic stem cell transplant recipient with Hodgkin lymphoma.
Jorge Chaves, Auris Huen, Carlos Bueso-Ramos, Amar Safdar, Saroj Vadhan-Raj

Clin Infect Dis· April 2006

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[Determining exposure history in occupational epidemiology].
Maria Teresa Espinosa, Timo Partanen, Marion Piñeros, Jorge Chaves, Héctor Posso

Rev Panam Salud Publica· September 2005

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Workplace carcinogen and pesticide exposures in Costa Rica.
Timo Partanen, Jorge Chaves, Catharina Wesseling, Fabio Chaverri, Patricia Monge

Int J Occup Environ Health· September 2003

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