Publications by authors named "Jorge Garcia-Fortanet"

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GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis.
Jonathan M Goodwin, Ward G Walkup, Kirsty Hooper, Taoyingnan Li, Chieko Kishi-Itakura, Jorge Garcia-Fortanet

Sci Adv· October 2021

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Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
Matthew J LaMarche, Michael Acker, Andreea Argintaru, Daniel Bauer, Julie Boisclair, Jorge Garcia-Fortanet

J Med Chem· November 2020

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Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.
Jorge Garcia Fortanet, Christine Hiu-Tung Chen, Ying-Nan P Chen, Zhouliang Chen, Zhan Deng

J Med Chem· September 2016

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Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Ying-Nan P Chen, Matthew J LaMarche, Ho Man Chan, Peter Fekkes, Jorge Garcia-Fortanet

Nature· July 2016

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Palladium(0)-catalyzed arylative dearomatization of phenols.
Sophie Rousseaux, Jorge García-Fortanet, Miguel Angel Del Aguila Sanchez, Stephen L Buchwald

J Am Chem Soc· June 2011

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Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides.
Donald A Watson, Mingjuan Su, Georgiy Teverovskiy, Yong Zhang, Jorge García-Fortanet

Science· September 2009

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Palladium-catalyzed asymmetric dearomatization of naphthalene derivatives.
Jorge García-Fortanet, Florian Kessler, Stephen L Buchwald

J Am Chem Soc· May 2009

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Asymmetric palladium-catalyzed intramolecular alpha-arylation of aldehydes.
Jorge García-Fortanet, Stephen L Buchwald

Angew Chem Int Ed Engl· December 2008

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Twofold C-H functionalization: palladium-catalyzed ortho arylation of anilides.
Gordon Brasche, Jorge García-Fortanet, Stephen L Buchwald

Org Lett· June 2008

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The total synthesis and biological properties of the cytotoxic macrolide FD-891 and its non-natural (Z)-C12 isomer.
Jorge García-Fortanet, Juan Murga, Miguel Carda, J Alberto Marco, Ruth Matesanz

Chemistry· September 2007

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Stereoselective synthesis of the cytotoxic macrolide FD-891.
Jorge García-Fortanet, Juan Murga, Miguel Carda, J Alberto Marco

Org Lett· June 2006

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An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones.
Claire E T Mitchell, Stacey E Brenner, Jorge García-Fortanet, Steven V Ley

Org Biomol Chem· May 2006

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Stereoselective total synthesis and absolute configuration of the natural decanolides (-)-microcarpalide and (+)-lethaloxin. Identity of (+)-lethaloxin and (+)-pinolidoxin.
Jorge García-Fortanet, Juan Murga, Eva Falomir, Miguel Carda, J Alberto Marco

J Org Chem· November 2005

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Synthesis and complete stereochemical assignment of psymberin/irciniastatin A.
Xin Jiang, Jorge García-Fortanet, Jef K De Brabander

J Am Chem Soc· August 2005

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A photochemical entry to depsides: synthesis of gustastatin.
Jorge García-Fortanet, John R Debergh, Jef K De Brabander

Org Lett· February 2005

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Stereoselective synthesis of the antiprotozoal lactone passifloricin A and seven isomers thereof.
Juan Murga, Jorge García-Fortanet, Miguel Carda, J Alberto Marco

J Org Chem· October 2004

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On the structure of passifloricin A: asymmetric synthesis of the delta-lactones of (2Z,5S,7R,9S,11S)- and (2Z,5R,7R,9S,11S)tetrahydroxyhexacos-2-enoic acid.
Jorge García-Fortanet, Juan Murga, Miguel Carda, J Alberto Marco

Org Lett· May 2003

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Stereoselective synthesis of microcarpalide.
Juan Murga, Eva Falomir, Jorge García-Fortanet, Miguel Carda, J Alberto Marco

Org Lett· October 2002

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