Publications by authors named "Jorge M David"

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The Flavonoid Agathisflavone Attenuates Glia Activation After Mechanical Injury of Cortical Tissue and Negatively Regulates Both NRLP3 and IL-1β Expression.
Verônica Moreira de Sousa, Áurea Maria Alves Nunes Almeida, Rafael Short Ferreira, Balbino Lino Dos Santos, Victor Diogenes Amara da Silva, Jorge Mauricio David

Int J Mol Sci· February 2025

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Chemical analysis and biological activity of crude extracts obtained from leaves of (Subg. ) and (Subg. Decaloba).
Ohana Luiza Santos de Oliveira, Oscar Caetano da Silva Neto, Gabriele Rodrigues Conceição, Fábio Alexandre Chinalia, Daniel Pereira Bezerra, Jorge Mauricio David

Nat Prod Res· February 2025

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The Biflavonoid Agathisflavone Regulates Microglial and Astrocytic Inflammatory Profiles via Glucocorticoid Receptor.
Áurea Maria Alves Nunes Almeida, Cleonice Creusa Dos Santos, Daniele Takahashi, Larissa Pereira da Silva, Verônica Moreira de Sousa, Jorge Mauricio David

Molecules· February 2025

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Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation.
Karina Costa da Silva, Irlã Santos Lima, Cleonice Creusa Dos Santos, Carolina Kymie Vasques Nonaka, Bruno Solano de Freitas Souza, Jorge Mauricio David

Molecules· January 2025

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Neuroprotective Effect of Flavonoid Agathisflavone in the Ex Vivo Cerebellar Slice Neonatal Ischemia.
Rodrigo Barreto Carreira, Cleonice Creusa Dos Santos, Juciele Valeria Ribeiro de Oliveira, Victor Diogenes Amaral da Silva, Jorge Maurício David

Molecules· September 2024

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Cytotoxic and antibacterial compounds from Raddi fruits.
Jennifer Blandón Pardo, Jorge Mauricio David, Alef Barros, Emiliano Barreto

Nat Prod Res· September 2024

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Seasonal and Circadian Variation of Non-Volatile Metabolites in Lippia alba Leaves.
Girlane Oliveira Rocha, Caroline Scabini, Jayne Ferreira da Silva Oliveira, Déborah Neres Oliveira, Luise Carvalho Mota, Jorge Maurício David

Chem Biodivers· July 2024

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The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling.
Balbino Lino Dos Santos, Cleonice Creusa Dos Santos, Karina Costa da Silva, Carolina Kymie Vasques Nonaka, Bruno Solano de Freitas Souza, Jorge Mauricio David

Int J Mol Sci· February 2024

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Hydroxytakakiamide and Other Constituents from a Marine Sponge-Associated Fungus MMERU23, and Antinociceptive Activity of Ergosterol Acetate, Acetylaszonalenin and Helvolic Acid.
Harol Ricardo Arias Cardona, Bruno Cerqueira da Silva, Flávia Oliveira de Lima, Franco Henrique Andrade Leite, Bruno Cruz de Souza, Jorge Maurício David

Mar Drugs· February 2024

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Microwave extraction and molecular imprinted polymer isolation of bergenin applied to the dendrochronological chemical study of Peltophorum dubium.
Oscar Caetano Silva-Neto, Caio Silva Assis Felix, Leonardo de Oliveira Aguiar, Mauricio Brandão Dos Santos, Silvio Cunha, Jorge Mauricio David

BMC Chem· January 2024

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The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome.
Balbino Lino Dos Santos, Cleonice Creusa Dos Santos, Janaina R P Soares, Karina C da Silva, Juciele Valeria R de Oliveira, Jorge Mauricio David

Pharmaceutics· May 2023

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Potential therapeutic effects of green tea on obese lipid profile - a systematic review.
Ana Paula Azevêdo Macêdo, Mariane Dos Santos Gonçalves, Jairza Maria Barreto Medeiros, Jorge Mauricio David, Cristiane Flora Villarreal, Ricardo David Couto

Nutr Health· September 2022

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Agathisflavone Modifies Microglial Activation State and Myelination in Organotypic Cerebellar Slices Culture.
Monique Marylin Alves de Almeida, Francesca Pieropan, Tim Footz, Jorge Mauricio David, Juceni Pereira David

J Neuroimmune Pharmacol· June 2022

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New dimer and trimer of chalcone derivatives from anti-inflammatory and antinociceptive extracts of Schinopsis brasiliensis roots.
Bruno Oliveira Moreira, Vanessa Lima Souza Vilar, Ramine Nascimento Santos de Almeida, Lorena Lôbo Brito Morbeck, Bruno Silva Andrade, Jorge Mauricio David

J Ethnopharmacol· May 2022

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Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats.
Ravena P do Nascimento, Lívia B de Jesus, Markley S Oliveira-Junior, Aurea M Almeida, Eduardo L T Moreira, Jorge M David

Front Pharmacol· April 2022

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Acetylcholinesterase inhibitory activity of extracts: HPLC-MS/MS characterization and molecular modeling studies.
Isabella M A Reis, Dayse S A Cassiano, Rodrigo S Conceição, Humberto F de Freitas, Samuel S da R Pita, Jorge M David

Nat Prod Res· February 2022

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Cytotoxic Activity of Tropane Alkaloides of Species of Erythroxylum.
José F Araújo Neto, Erika M de O Ribeiro, Ademir E do Vale, Jorge M David, Juceni P David

Mini Rev Med Chem· December 2021

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Reverted effect of mesenchymal stem cells in glioblastoma treated with agathisflavone and its selective antitumoral effect on cell viability, migration, and differentiation via STAT3.
Ravena P Nascimento, Balbino L Dos Santos, Karina C da Silva, Victor D Amaral da Silva, Maria de Fátima Costa, Jorge M David, Juceni P David

J Cell Physiol· July 2021

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Chemical Strategies towards the Synthesis of Betulinic Acid and Its More Potent Antiprotozoal Analogues.
André Barreto Cunha, Ronan Batista, María Ángeles Castro, Jorge Mauricio David

Molecules· February 2021

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Agathisflavone modulates astrocytic responses and increases the population of neurons in an in vitro model of traumatic brain injury.
Vanessa Cristina Meira de Amorim, Markley Silva Oliveira Júnior, Alessandra Bispo da Silva, Jorge M David, Juceni Pereira Lima David

Naunyn Schmiedebergs Arch Pharmacol· October 2020

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The Flavonoid Agathisflavone from Poincianella pyramidalis Prevents Aminochrome Neurotoxicity.
Cleonice Creusa Santos, Patricia Muñoz, Áurea Maria A N Almeida, Juceni Pereira de Lima David, Jorge Mauricio David

Neurotox Res· October 2020

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Cytotoxic, Antitumor and Toxicological Profile of Leaf Extract.
Ricardo G Amaral, Silvana V F Gomes, Luciana N Andrade, Sara A Dos Santos, Patrícia Severino, Jorge M David

Molecules· October 2020

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The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination.
Monique Marylin Alves de Almeida, Francesca Pieropan, Larissa de Mattos Oliveira, Manoelito Coelho Dos Santos Junior, Jorge Mauricio David, Juceni Pereira David

Pharmacol Res· September 2020

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Bergenin Reduces Experimental Painful Diabetic Neuropathy by Restoring Redox and Immune Homeostasis in the Nervous System.
Cristiane F Villarreal, Dourivaldo S Santos, Pedro S S Lauria, Kelly B Gama, Renan F Espírito-Santo, Jorge M David

Int J Mol Sci· July 2020

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Brazilian Red Propolis: Extracts Production, Physicochemical Characterization, and Cytotoxicity Profile for Antitumor Activity.
Felipe Mendes de Andrade de Carvalho, Jaderson Kleveston Schneider, Carla Viviane Freitas de Jesus, Luciana Nalone de Andrade, Ricardo Guimarães Amaral, Jorge Maurício David

Biomolecules· May 2020

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