Publications by authors named "Jorge Ruas"

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Sensory-neuron-derived CGRPα controls white adipocyte differentiation and tissue plasticity.
Kyle D Dumont, Saba Seradj, Yu Wang, Shanshan Liu, Igor Cervenka, Jorge L Ruas

Cell Rep· November 2025

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Endurance exercise with reduced muscle glycogen content influences substrate utilization and attenuates acute mTORC1- and autophagic signaling in human type I and type II muscle fibers.
Oscar Horwath, Lucas Cornet, Henrik Strömlind, Marcus Moberg, Sebastian Edman, Jorge L Ruas

Skelet Muscle· March 2025

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Constitutive loss of kynurenine-3-monooxygenase changes circulating kynurenine metabolites without affecting systemic energy metabolism.
Kyle D Dumont, Paulo R Jannig, Margareta Porsmyr-Palmertz, Jorge L Ruas

Am J Physiol Endocrinol Metab· February 2025

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Senescence detection using reflected light.
Benjamin Dedic, Leo Westerberg, Andrea Mosqueda Solís, Kyle D Dumont, Jorge L Ruas

Aging Cell· November 2024

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The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms.
Tang Cam Phung Pham, Steffen Henning Raun, Essi Havula, Carlos Henriquez-Olguín, Diana Rubalcava-Gracia, Jorge L Ruas

Nat Commun· November 2024

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Risk Factors Associated with Weight Gain during Treatment with Dupilumab among Patients with Moderate to Severe Atopic Dermatitis.
Mahsa Tayefi, Axel Svedbom, Lina Ivert, Maria Lundqvist, Jorge Ruas

Acta Derm Venereol· November 2024

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Mood, Cognitive Function, and Plasma Kynurenine Metabolites Responses Following Severe Changes in Physical Activity.
Sigitas Kamandulis, Inga Lukonaitiene, Audrius Snieckus, Marius Brazaitis, Mantas Mickevicius, Jorge Ruas

Med Sci Sports Exerc· October 2024

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A 2-hydroxybutyrate-mediated feedback loop regulates muscular fatigue.
Brennan J Wadsworth, Marina Leiwe, Eleanor A Minogue, Pedro P Cunha, Viktor Engman, Jorge L Ruas

Elife· September 2024

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Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling.
Jorge C Correia, Paulo R Jannig, Maya L Gosztyla, Igor Cervenka, Serge Ducommun, Jorge L Ruas

Proc Natl Acad Sci U S A· August 2024

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Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.
Serge Ducommun, Paulo R Jannig, Igor Cervenka, Marta Murgia, Melanie J Mittenbühler, Jorge L Ruas

Mol Metab· April 2024

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Multivalent insulin receptor activation using insulin-DNA origami nanostructures.
Joel Spratt, José M Dias, Christina Kolonelou, Georges Kiriako, Enya Engström, Jorge L Ruas

Nat Nanotechnol· February 2024

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NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease.
Inês Caria, Maria João Nunes, Viviana Ciraci, Andreia Neves Carvalho, Catarina Ranito, Jorge L Ruas

Biochim Biophys Acta Mol Basis Dis· February 2024

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Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration.
Jorge C Correia, Paulo R Jannig, Maya L Gosztyla, Igor Cervenka, Serge Ducommun, Jorge L Ruas

bioRxiv· June 2023

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Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling.
Joana Saraiva Rodrigues, Andreia Faria-Pereira, Sérgio Póvoas Camões, Ana Sofia Serras, Vanessa Alexandra Morais, Jorge Lira Ruas

Front Endocrinol (Lausanne)· January 2023

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Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence.
Qing Luo, Han-Pin Pui, Jiayu Chen, Leqian Yu, Paulo R Jannig, Jorge L Ruas

Cell Rep· January 2023

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Publisher Correction: Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome.
Shuijie Li, Wenyu Li, Juan Yuan, Petra Bullova, Jieyu Wu, Jorge L Ruas

Nat Metab· October 2022

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Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias.
Hannes Schihada, Thomas M Klompstra, Laura J Humphrys, Igor Cervenka, Shamim Dadvar, Jorge L Ruas

J Biol Chem· September 2022

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PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes.
Tomi Tuomainen, Nikolay Naumenko, Maija Mutikainen, Anastasia Shakirzyanova, Sarah Sczelecki, Jorge L Ruas

Cells· September 2022

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Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity.
Daniel Oehler, André Spychala, Axel Gödecke, Alexander Lang, Norbert Gerdes, Jorge Ruas

BMC Biol· July 2022

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Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome.
Shuijie Li, Wenyu Li, Juan Yuan, Petra Bullova, Jieyu Wu, Jorge L Ruas

Nat Metab· June 2022

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SnapShot: Regulation and biology of PGC-1α.
Paulo R Jannig, Phillip A Dumesic, Bruce M Spiegelman, Jorge L Ruas

Cell· April 2022

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HIF-1α inhibitor PX-478 preserves pancreatic β cell function in diabetes.
Erwin Ilegems, Galyna Bryzgalova, Jorge Correia, Burcak Yesildag, Edurne Berra, Jorge L Ruas

Sci Transl Med· March 2022

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Changes in plasma concentration of kynurenine following intake of branched-chain amino acids are not caused by alterations in muscle kynurenine metabolism.
William O Jonsson, Jonathan Ponette, Oscar Horwath, Tomas Rydenstam, Karin Söderlund, Jorge L Ruas

Am J Physiol Cell Physiol· January 2022

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Mitochondrial NDUFA4L2 is a novel regulator of skeletal muscle mass and force.
Zhengye Liu, Thomas Chaillou, Estela Santos Alves, Theresa Mader, Baptiste Jude, Jorge L Ruas

FASEB J· December 2021

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Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism.
Julie Massart, Rasmus J O Sjögren, Brendan Egan, Christian Garde, Magnus Lindgren, Jorge L Ruas

Nat Commun· October 2021

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