Publications by authors named "Jose L Orgaz"

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Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis.
Oscar Maiques, Marta C Sallan, Roman Laddach, Pahini Pandya, Adrian Varela, Jose L Orgaz

Nat Commun· February 2025

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Creating a path during melanoma amoeboid migration: When too crowded, start worrying.
Jose L Orgaz

Dev Cell· September 2024

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CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.
Remi Samain, Oscar Maiques, Joanne Monger, Hoyin Lam, Juliana Candido, Jose L Orgaz

Sci Adv· October 2023

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Cytoskeletal Remodelling as an Achilles' Heel for Therapy Resistance in Melanoma.
Adrian Barreno, Jose L Orgaz

Cells· February 2022

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Rho GTPase signaling in cancer progression and dissemination.
Eva Crosas-Molist, Remi Samain, Leonie Kohlhammer, Jose L Orgaz, Samantha L George

Physiol Rev· January 2022

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A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
Oscar Maiques, Bruce Fanshawe, Eva Crosas-Molist, Irene Rodriguez-Hernandez, Alessia Volpe, Jose L Orgaz

Br J Cancer· August 2021

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WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion.
Irene Rodriguez-Hernandez, Oscar Maiques, Leonie Kohlhammer, Gaia Cantelli, Anna Perdrix-Rosell, Jose L Orgaz

Nat Commun· October 2020

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CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion.
Aaron J Farrugia, Javier Rodríguez, Jose L Orgaz, María Lucas, Victoria Sanz-Moreno

J Cell Biol· September 2020

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What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation.
Jose L Orgaz, Victoria Sanz-Moreno

Mol Cell Oncol· March 2020

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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance.
Jose L Orgaz, Eva Crosas-Molist, Amine Sadok, Anna Perdrix-Rosell, Oscar Maiques

Cancer Cell· January 2020

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Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment.
Mirella Georgouli, Cecilia Herraiz, Eva Crosas-Molist, Bruce Fanshawe, Oscar Maiques, Jose L Orgaz

Cell· February 2019

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T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1.
Oscar Maiques, Carla Barceló, Anaïs Panosa, Jordi Pijuan, Jose L Orgaz

Pigment Cell Melanoma Res· July 2018

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Actomyosin contractility and collective migration: may the force be with you.
Pahini Pandya, Jose L Orgaz, Victoria Sanz-Moreno

Curr Opin Cell Biol· October 2017

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Modes of invasion during tumour dissemination.
Pahini Pandya, Jose L Orgaz, Victoria Sanz-Moreno

Mol Oncol· January 2017

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Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination.
Cecilia Herraiz, Fernando Calvo, Pahini Pandya, Gaia Cantelli, Irene Rodriguez-Hernandez, Jose L Orgaz

J Natl Cancer Inst· January 2016

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TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.
Gaia Cantelli, Jose L Orgaz, Irene Rodriguez-Hernandez, Panagiotis Karagiannis, Oscar Maiques

Curr Biol· November 2015

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Microphthalmia-Associated Transcription Factor: A Central Regulator of Pigment Epithelium-Derived Factor Controlling Human Melanoma Progression.
Benilde Jiménez Cuenca, Asunción Fernández-Barral, José Luis Orgaz

Am J Pathol· July 2015

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Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.
Óscar Aguilera, José Manuel González-Sancho, Sandra Zazo, Raúl Rincón, Agustín F Fernández, José L Orgaz

Oncotarget· March 2015

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Rho GTPases modulate malignant transformation of tumor cells.
Jose L Orgaz, Cecilia Herraiz, Victoria Sanz-Moreno

Small GTPases· February 2015

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Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.
Jose L Orgaz, Pahini Pandya, Rimple Dalmeida, Panagiotis Karagiannis, Berta Sanchez-Laorden

Nat Commun· June 2014

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Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma.
Asunción Fernández-Barral, Jose Luis Orgaz, Pablo Baquero, Zaheer Ali, Alberto Moreno

Neoplasia· June 2014

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(V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism.
Pablo Baquero, Irene Sánchez-Hernández, Eva Jiménez-Mora, Jose L Orgaz, Benilde Jiménez

Cancer Lett· July 2013

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Cellular plasticity confers migratory and invasive advantages to a population of glioblastoma-initiating cells that infiltrate peritumoral tissue.
Patricia Ruiz-Ontañon, Jose L Orgaz, Beatriz Aldaz, Alberto Elosegui-Artola, Juan Martino

Stem Cells· June 2013

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Emerging molecular targets in melanoma invasion and metastasis.
Jose L Orgaz, Victoria Sanz-Moreno

Pigment Cell Melanoma Res· January 2013

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Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism.
Asunción Fernández-Barral, José Luis Orgaz, Valentí Gomez, Luis del Peso, María José Calzada

PLoS One· August 2012

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