Publications by authors named "Joseph Chiesa"

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Pharmacokinetics of Intravenous Finafloxacin in Healthy Volunteers.
Max Taubert, Joseph Chiesa, Mark Lückermann, Carsten Fischer, Axel Dalhoff

Antimicrob Agents Chemother· October 2017

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Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate.
Tracy S Zimmermann, Verena Karsten, Amy Chan, Joseph Chiesa, Malcolm Boyce

Mol Ther· January 2017

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A phase 1 study to evaluate the safety and pharmacokinetics of PQ912, a glutaminyl cyclase inhibitor, in healthy subjects.
Inge Lues, Frank Weber, Antje Meyer, Uli Bühring, Torsten Hoffmann, Joseph Chiesa

Alzheimers Dement (N Y)· November 2015

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Safety, pharmacokinetics, pharmacogenomics and QT concentration-effect modelling of the SirT1 inhibitor selisistat in healthy volunteers.
Goran Westerberg, Joseph A Chiesa, Claus A Andersen, Daniela Diamanti, Letizia Magnoni

Br J Clin Pharmacol· March 2015

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Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial.
Kevin Fitzgerald, Maria Frank-Kamenetsky, Svetlana Shulga-Morskaya, Abigail Liebow, Brian R Bettencourt, Joseph Chiesa

Lancet· January 2014

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Safety and efficacy of RNAi therapy for transthyretin amyloidosis.
Teresa Coelho, David Adams, Ana Silva, Pierre Lozeron, Philip N Hawkins, Joseph Chiesa

N Engl J Med· August 2013

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QT effect of semagacestat at therapeutic and supratherapeutic doses.
Wei Zhang, Mosun Ayan-Oshodi, Brian A Willis, William Annes, Stephen D Hall, Joseph Chiesa

Int J Clin Pharmacol Ther· April 2012

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