Publications by authors named "Joseph D Butner"

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Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer.
Prashant Dogra, Vrushaly Shinglot, Javier Ruiz-Ramírez, Joseph Cave, Joseph D Butner

Mol Cancer· August 2024

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Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy.
Joseph D Butner, Prashant Dogra, Caroline Chung, Eugene J Koay, James W Welsh

NPJ Syst Biol Appl· August 2024

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Development of a Multiscale Mechanistic Model for Predicting Tumor Response to Anti-miR-155.
Prashant Dogra, Joseph D Butner, Vittorio Cristini, Zhihui Wang

Annu Int Conf IEEE Eng Med Biol Soc· July 2024

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Translational modeling-based evidence for enhanced efficacy of standard-of-care drugs in combination with anti-microRNA-155 in non-small-cell lung cancer.
Prashant Dogra, Vrushaly Shinglot, Javier Ruiz-Ramírez, Joseph Cave, Joseph D Butner

medRxiv· March 2024

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Hybridizing mechanistic mathematical modeling with deep learning methods to predict individual cancer patient survival after immune checkpoint inhibitor therapy.
Joseph D Butner, Prashant Dogra, Caroline Chung, Eugene J Koay, James W Welsh

Res Sq· March 2024

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Mechanistic modeling of anti-microRNA-155 therapy combinations in lung cancer.
Joseph Cave, Vrushaly Shinglot, Joseph D Butner, Vittorio Cristini, Bulent Ozpolat

Annu Int Conf IEEE Eng Med Biol Soc· July 2023

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Immune-checkpoint inhibitor therapy response evaluation using oncophysics-based mathematical models.
Mustafa Syed, Matthew Cagely, Prashant Dogra, Lauren Hollmer, Joseph D Butner

Wiley Interdiscip Rev Nanomed Nanobiotechnol· March 2023

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Protocol for mathematical prediction of patient response and survival to immune checkpoint inhibitor immunotherapy.
Joseph D Butner, Maguy Farhat, Vittorio Cristini, Caroline Chung, Zhihui Wang

STAR Protoc· December 2022

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Mathematical modeling of cancer immunotherapy for personalized clinical translation.
Joseph D Butner, Prashant Dogra, Caroline Chung, Renata Pasqualini, Wadih Arap

Nat Comput Sci· December 2022

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A Phase 2 Trial of Enhancing Immune Checkpoint Blockade by Stereotactic Radiation and In Situ Virus Gene Therapy in Metastatic Triple-Negative Breast Cancer.
Kai Sun, Yitian Xu, Licheng Zhang, Polly Niravath, Jorge Darcourt, Joseph D Butner

Clin Cancer Res· October 2022

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Mass Transport Model of Radiation Response: Calibration and Application to Chemoradiation for Pancreatic Cancer.
Charles X Wang, Dalia Elganainy, Mohamed M Zaid, Joseph D Butner, Anshuman Agrawal

Int J Radiat Oncol Biol Phys· September 2022

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Dedifferentiation-mediated stem cell niche maintenance in early-stage ductal carcinoma in situ progression: insights from a multiscale modeling study.
Joseph D Butner, Prashant Dogra, Caroline Chung, Javier Ruiz-Ramírez, Sara Nizzero

Cell Death Dis· May 2022

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Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer.
Prashant Dogra, Javier Ruiz Ramírez, Joseph D Butner, Maria J Peláez, Caroline Chung

Pharm Res· March 2022

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Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling.
Joseph D Butner, Geoffrey V Martin, Zhihui Wang, Bruna Corradetti, Mauro Ferrari

Elife· November 2021

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A Multiscale Model to Identify Limiting Factors in Nanoparticle-Based miRNA Delivery for Tumor Inhibition.
Prashant Dogra, Javier Ruiz Ramirez, Joseph D Butner, Maria J Pelaez, Vittorio Cristini

Annu Int Conf IEEE Eng Med Biol Soc· November 2021

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Predicting immune checkpoint inhibitor response with mathematical modeling.
Joseph D Butner, Zhihui Wang

Immunotherapy· October 2021

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A mathematical model for the quantification of a patient's sensitivity to checkpoint inhibitors and long-term tumour burden.
Joseph D Butner, Zhihui Wang, Dalia Elganainy, Karine A Al Feghali, Marija Plodinec

Nat Biomed Eng· April 2021

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Corrections to "A multiscale Agent-Based Model of Ductal Carcinoma in Situ".
Joseph D Butner, David Fuentes, Bulent Ozpolat, George A Calin, Xiaobo Zhou

IEEE Trans Biomed Eng· February 2021

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Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model.
Prashant Dogra, Javier Ruiz-Ramírez, Kavya Sinha, Joseph D Butner, Maria J Peláez

ACS Pharmacol Transl Sci· February 2021

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A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases.
Daniel A Anaya, Prashant Dogra, Zhihui Wang, Mintallah Haider, Jasmina Ehab, Joseph D Butner

Cancers (Basel)· January 2021

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Innate immunity plays a key role in controlling viral load in COVID-19: mechanistic insights from a whole-body infection dynamics model.
Prashant Dogra, Javier Ruiz-Ramírez, Kavya Sinha, Joseph D Butner, Maria J Peláez

medRxiv· November 2020

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Image-guided mathematical modeling for pharmacological evaluation of nanomaterials and monoclonal antibodies.
Prashant Dogra, Joseph D Butner, Sara Nizzero, Javier Ruiz Ramírez, Achraf Noureddine

Wiley Interdiscip Rev Nanomed Nanobiotechnol· September 2020

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Investigating the Effect of Aging on the Pharmacokinetics and Tumor Delivery of Nanomaterials using Mathematical Modeling.
Prashant Dogra, Joseph D Butner, Javier Ruiz Ramirez, Vittorio Cristini, Zhihui Wang

Annu Int Conf IEEE Eng Med Biol Soc· July 2020

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Mathematical prediction of clinical outcomes in advanced cancer patients treated with checkpoint inhibitor immunotherapy.
Joseph D Butner, Dalia Elganainy, Charles X Wang, Zhihui Wang, Shu-Hsia Chen

Sci Adv· May 2020

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A mathematical model to predict nanomedicine pharmacokinetics and tumor delivery.
Prashant Dogra, Joseph D Butner, Javier Ruiz Ramírez, Yao-Li Chuang, Achraf Noureddine

Comput Struct Biotechnol J· February 2020

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