Publications by authors named "Joseph D Szustakowski"

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Proteome-Wide Mendelian Randomization Identifies Candidate Causal Proteins for Cardiovascular Diseases.
Chen Li, Nicolas De Jay, Shan-Shan Zhang, Xin Fang, Supriya Sharma, Joseph D Szustakowski

Adv Genet (Hoboken)· June 2025

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A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer.
Mike Mason, Óscar Lapuente-Santana, Anni S Halkola, Wenyu Wang, Raghvendra Mall, Joseph D Szustakowski

J Transl Med· February 2024

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Pursuing Better Biomarkers for Immunotherapy Response in Cancer Through a Crowdsourced Data Challenge.
Benjamin G Vincent, Joseph D Szustakowski, Parul Doshi, Michael Mason, Justin Guinney

JCO Precis Oncol· November 2021

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Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.
Jack A Kosmicki, Julie E Horowitz, Nilanjana Banerjee, Rouel Lanche, Anthony Marcketta, Joseph D Szustakowski

Am J Hum Genet· July 2021

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Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank.
Joseph D Szustakowski, Suganthi Balasubramanian, Erika Kvikstad, Shareef Khalid, Paola G Bronson

Nat Genet· July 2021

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First-Line Nivolumab Plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer (CheckMate 568): Outcomes by Programmed Death Ligand 1 and Tumor Mutational Burden as Biomarkers.
Neal Ready, Matthew D Hellmann, Mark M Awad, Gregory A Otterson, Martin Gutierrez, Joseph D Szustakowski

J Clin Oncol· April 2019

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Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer.
Matthew D Hellmann, Margaret K Callahan, Mark M Awad, Emiliano Calvo, Paolo A Ascierto, Joseph D Szustakowski

Cancer Cell· February 2019

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Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung Cancer.
Matthew D Hellmann, Margaret K Callahan, Mark M Awad, Emiliano Calvo, Paolo A Ascierto, Joseph D Szustakowski

Cancer Cell· May 2018

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Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors.
Nathan O Siemers, James L Holloway, Han Chang, Scott D Chasalow, Petra B Ross-MacDonald, Joseph D Szustakowski

PLoS One· October 2017

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Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.
Albane A Bizet, Anita Becker-Heck, Rebecca Ryan, Kristina Weber, Emilie Filhol, Joseph D Szustakowski

Nat Commun· October 2015

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Whole-exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis.
Kenneth M Kaufman, Bolan Linghu, Joseph D Szustakowski, Ammar Husami, Fan Yang

Arthritis Rheumatol· December 2014

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The use of haplotype-specific transcripts improves sample annotation consistency.
Nicole Hartmann, Evert Luesink, Edward Khokhlovich, Joseph D Szustakowski, Lukas Baeriswyl

Biomark Res· October 2014

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RAMP: a bioinformatics framework for researching imaging agents through molecular pathways.
Edward Khokhlovich, Daniel Wahl, Anthony Masiello, Pierre Parisot, Stefan El-Ghatta, Joseph D Szustakowski

Mol Imaging· July 2013

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LMX1B mutations cause hereditary FSGS without extrarenal involvement.
Olivia Boyer, Stéphanie Woerner, Fan Yang, Edward J Oakeley, Bolan Linghu, Joseph D Szustakowski

J Am Soc Nephrol· July 2013

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DeconRNASeq: a statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data.
Ting Gong, Joseph D Szustakowski

Bioinformatics· April 2013

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Optimal deconvolution of transcriptional profiling data using quadratic programming with application to complex clinical blood samples.
Ting Gong, Nicole Hartmann, Isaac S Kohane, Volker Brinkmann, Frank Staedtler, Joseph D Szustakowski

PLoS One· March 2012

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Transcriptome changes in renal allograft protocol biopsies at 3 months precede the onset of interstitial fibrosis/tubular atrophy (IF/TA) at 6 months.
Andreas Scherer, Wilfried Gwinner, Michael Mengel, Torsten Kirsch, Friedrich Raulf, Joseph D Szustakowski

Nephrol Dial Transplant· August 2009

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Identification of novel genes and pathways regulating SREBP transcriptional activity.
Sandipan Chatterjee, Joseph D Szustakowski, Nirmala R Nanguneri, Craig Mickanin, Mark A Labow

PLoS One· July 2009

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Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles.
Qicheng Ma, Gung-Wei Chirn, Joseph D Szustakowski, Adel Bakhtiarova, Penelope A Kosinski

BioData Min· July 2008

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Extending the pathway analysis framework with a test for transcriptional variance implicates novel pathway modulation during myogenic differentiation.
Daniel M Kemp, N R Nirmala, Joseph D Szustakowski

Bioinformatics· June 2007

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Dynamic resolution of functionally related gene sets in response to acute heat stress.
Joseph D Szustakowski, Penelope A Kosinski, Christine A Marrese, Jee-Hyung Lee, Stephen J Elliman

BMC Mol Biol· June 2007

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Pyruvate induces mitochondrial biogenesis by a PGC-1 alpha-independent mechanism.
Leanne Wilson, Qing Yang, Joseph D Szustakowski, P Scott Gullicksen, Reza Halse

Am J Physiol Cell Physiol· May 2007

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Identification of novel pathway regulation during myogenic differentiation.
Joseph D Szustakowski, Jee-Hyung Lee, Christine A Marrese, Penelope A Kosinski, N R Nirmala

Genomics· January 2006

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Less is more: towards an optimal universal description of protein folds.
Joseph D Szustakowski, Simon Kasif, Zhiping Weng

Bioinformatics· September 2005

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