Publications by authors named "Joseph G Shaddock"

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Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Daishiro Miura, Robert H Heflich

Methods Mol Biol· November 2025

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Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Robert H Heflich

Methods Mol Biol· October 2020

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Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Daishiro Miura, Robert H Heflich

Methods Mol Biol· April 2020

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Analysis of in vivo mutation in the Hprt and Tk genes of mouse lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Robert H Heflich

Methods Mol Biol· November 2014

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Detection of in vivo mutation in the Hprt and Pig-a genes of rat lymphocytes.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Daishiro Miura, Robert H Heflich

Methods Mol Biol· February 2014

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Nitroxide TEMPO: a genotoxic and oxidative stress inducer in cultured cells.
Xiaoqing Guo, Roberta A Mittelstaedt, Lei Guo, Joseph G Shaddock, Robert H Heflich

Toxicol In Vitro· August 2013

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Sensitivity of the Pig-a assay for detecting gene mutation in rats exposed acutely to strong clastogens.
Javed A Bhalli, Joseph G Shaddock, Mason G Pearce, Vasily N Dobrovolsky

Mutagenesis· July 2013

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Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, aristolochic acids.
Javed A Bhalli, Wei Ding, Joseph G Shaddock, Mason G Pearce, Vasily N Dobrovolsky

Mutat Res· May 2013

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In vivo genotoxicity of furan in F344 rats at cancer bioassay doses.
Wei Ding, Dayton M Petibone, John R Latendresse, Mason G Pearce, Levan Muskhelishvili, Joseph G Shaddock

Toxicol Appl Pharmacol· June 2012

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Genotoxicity of furan in Big Blue rats.
L Patrice McDaniel, Wei Ding, Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt

Mutat Res· February 2012

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Report on stage III Pig-a mutation assays using benzo[a]pyrene.
Javed A Bhalli, Joseph G Shaddock, Mason G Pearce, Vasily N Dobrovolsky, Xuefei Cao

Environ Mol Mutagen· December 2011

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Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-comparison with other in vivo genotoxicity endpoints.
Zoryana Cammerer, Javed A Bhalli, Xuefei Cao, Stephanie L Coffing, Donna Dickinson, Joseph G Shaddock

Environ Mol Mutagen· December 2011

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Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines.
Rahat Ali, Roberta A Mittelstaedt, Joseph G Shaddock, Wei Ding, Javed A Bhalli

Mutat Res· July 2011

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Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl-N-nitrosourea-treated fisher 344 rats.
Daishiro Miura, Joseph G Shaddock, Roberta A Mittelstaedt, Vasily N Dobrovolsky, Takafumi Kimoto

Environ Mol Mutagen· June 2011

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The genotoxicity of acrylamide and glycidamide in big blue rats.
Nan Mei, Lea P McDaniel, Vasily N Dobrovolsky, Xiaoqing Guo, Joseph G Shaddock

Toxicol Sci· June 2010

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Evaluation of mutagenic mode of action in Big Blue mice fed methylphenidate for 24 weeks.
Mugimane G Manjanatha, Sharon D Shelton, Vasily N Dobrovolsky, Joseph G Shaddock, Lynda G McGarrity

Mutat Res· April 2010

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DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide.
Linda S Von Tungeln, Mona I Churchwell, Daniel R Doerge, Joseph G Shaddock, Lynda J McGarrity

Int J Cancer· May 2009

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Evaluation of Macaca mulatta as a model for genotoxicity studies.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Mugimane G Manjanatha, Daishiro Miura

Mutat Res· February 2009

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The genetic toxicology of methylphenidate hydrochloride in non-human primates.
Suzanne M Morris, Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Michelle E Bishop

Mutat Res· February 2009

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Pharmacokinetics, dose-range, and mutagenicity studies of methylphenidate hydrochloride in B6C3F1 mice.
Mugimane G Manjanatha, Sharon D Shelton, Vasily N Dobrovolsky, Joseph G Shaddock, Lynda G McGarrity

Environ Mol Mutagen· October 2008

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Frequency and spectrum of ENU-induced mutation in the Phi X174 transgene in mouse splenic lymphocytes and their significance to spontaneous transgenic rodent mutation frequencies.
Carrie R Valentine, Heather F Rainey, Jessica M Farrell, Joseph G Shaddock, Vasily N Dobrovolsky

Mutagenesis· September 2008

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Effect of chronic azathioprine treatment on germ-line transmission of Hprt mutation in mice.
Sachin V Bendre, Joseph G Shaddock, Vasily N Dobrovolsky, Richard J Albertini, Robert H Heflich

Environ Mol Mutagen· December 2007

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Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.
Linda S Von Tungeln, Lee D Williams, Daniel R Doerge, Joseph G Shaddock, Lynda J McGarrity

Environ Mol Mutagen· May 2007

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Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.
Vasily N Dobrovolsky, Joseph G Shaddock, Roberta A Mittelstaedt, Michelle E Bishop, Sherry M Lewis

Environ Mol Mutagen· May 2007

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Frequency and types of spontaneous Hprt lymphocyte mutations in Pms2-deficient mice.
Joseph G Shaddock, Vasily N Dobrovolsky, Roberta A Mittelstaedt, Robert H Heflich, Barbara L Parsons

Mutat Res· March 2006

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