Publications by authors named "Joseph Guiles"

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Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors.
Joseph W Guiles, Andras Toro, Urs A Ochsner, James M Bullard

Org Med Chem Lett· February 2012

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Discovery and analysis of 4H-pyridopyrimidines, a class of selective bacterial protein synthesis inhibitors.
Wendy Ribble, Walter E Hill, Urs A Ochsner, Thale C Jarvis, Joseph W Guiles

Antimicrob Agents Chemother· November 2010

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Spectrum of activity and mode of action of REP3123, a new antibiotic to treat Clostridium difficile infections.
Ian A Critchley, Louis S Green, Casey L Young, James M Bullard, Ron J Evans, Joseph W Guiles

J Antimicrob Chemother· May 2009

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Quinazolin-2-ylamino-quinazolin-4-ols as novel non-nucleoside inhibitors of bacterial DNA polymerase III.
Joseph Guiles, Xicheng Sun, Ian A Critchley, Urs Ochsner, Ming Tregay

Bioorg Med Chem Lett· February 2009

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Grignard cross-coupling amenable to large scale production of alpha-fluorostyryl and alpha-fluorovinylthiophenes.
Jian Qiu, Albert Gyorokos, Theodore M Tarasow, Joseph Guiles

J Org Chem· December 2008

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Structure of PolC reveals unique DNA binding and fidelity determinants.
Ronald J Evans, Douglas R Davies, James M Bullard, Jeffrey Christensen, Louis S Green, Joseph W Guiles

Proc Natl Acad Sci U S A· December 2008

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New agents for Clostridium difficile-associated disease.
Joseph Guiles, Ian Critchley, Xicheng Sun

Expert Opin Investig Drugs· November 2008

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Antibacterial activity of REP8839, a new antibiotic for topical use.
Ian A Critchley, Casey L Young, Kimberley C Stone, Urs A Ochsner, Joseph Guiles

Antimicrob Agents Chemother· October 2005

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A Visual Tagging Process for Mix and Sort Combinatorial Chemistry.
Joseph W Guiles, Carolina L Lanter, Ralph A Rivero

Angew Chem Int Ed Engl· April 1998

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