Publications by authors named "Joseph Hypolite"

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Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2.
Elham Javed, Chellappagounder Thangavel, Nagat Frara, Jagmohan Singh, Ipsita Mohanty, Joseph Hypolite

FASEB J· February 2020

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Differential neurodegenerative phenotypes are associated with heterogeneous voiding dysfunction in a coronavirus-induced model of multiple sclerosis.
Sanghee Lee, Balachandar Nedumaran, Joseph Hypolite, Brian Caldwell, Michael C Rudolph

Sci Rep· July 2019

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Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel.
Ricardo H Pineda, Joseph Hypolite, Sanghee Lee, Alonso Carrasco, Nao Iguchi

BMC Urol· May 2019

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Altered expression and modulation of the two-pore-domain (K) mechanogated potassium channel TREK-1 in overactive human detrusor.
Ricardo H Pineda, Balachandar Nedumaran, Joseph Hypolite, Xiao-Qing Pan, Shandra Wilson

Am J Physiol Renal Physiol· August 2017

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Regulation of urinary bladder function by protein kinase C in physiology and pathophysiology.
Joseph A Hypolite, Anna P Malykhina

BMC Urol· November 2015

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Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms.
Joseph A Hypolite, Shaohua Chang, Alan J Wein, Samuel Chacko, Anna P Malykhina

BMC Urol· April 2015

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Effects of Rho-kinase inhibition on myosin light chain phosphorylation and obstruction-induced detrusor overactivity.
James O Marx, Maureen E Basha, Sunish Mohanan, Joseph A Hypolite, Shaohua Chang

Int J Urol· March 2014

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Amino acid mutations in the caldesmon COOH-terminal functional domain increase force generation in bladder smooth muscle.
Maoxian Deng, Ettickan Boopathi, Joseph A Hypolite, Tobias Raabe, Shaohua Chang

Am J Physiol Renal Physiol· November 2013

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Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels.
Joseph A Hypolite, Qi Lei, Shaohua Chang, Stephen A Zderic, Stephan Butler

Am J Physiol Renal Physiol· March 2013

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GATA-6 and NF-κB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contraction.
Ettickan Boopathi, Joseph A Hypolite, Stephen A Zderic, Cristiano Mendes Gomes, Bruce Malkowicz

Mol Cell Biol· March 2013

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Acute colonic inflammation triggers detrusor instability via activation of TRPV1 receptors in a rat model of pelvic organ cross-sensitization.
Tirsit S Asfaw, Joseph Hypolite, Gina M Northington, Lily A Arya, Alan J Wein

Am J Physiol Regul Integr Comp Physiol· June 2011

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Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein.
Shaohua Chang, Cristiano Mendes Gomes, Joseph A Hypolite, James Marx, Jaber Alanzi

Am J Physiol Renal Physiol· June 2010

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Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder.
Shaohua Chang, Joseph A Hypolite, Sunish Mohanan, Stephen A Zderic, Alan J Wein

Lab Invest· July 2009

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Deletion of SM-B, the high ATPase isoform of myosin, upregulates the PKC-mediated signal transduction pathway in murine urinary bladder smooth muscle.
Joseph A Hypolite, Shaohua Chang, Edward LaBelle, Gopal J Babu, Muthu Periasamy

Am J Physiol Renal Physiol· March 2009

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Lipid signaling changes in smooth muscle remodeling associated with partial urinary bladder outlet obstruction.
Edward LaBelle, Stephen Zderic, Daniel Delaney, Joseph Hypolite, Alan Wein

Neurourol Urodyn· May 2006

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Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17.
Shaohua Chang, Joseph A Hypolite, Michael E DiSanto, Arun Changolkar, Alan J Wein

Am J Physiol Renal Physiol· March 2006

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Partial bladder outlet obstruction induces urethral smooth muscle hypertrophy and decreased force generation.
Joseph A Hypolite, Shaohua Chang, Yongmu Zheng, Michael E DiSanto, Stephen A Zderic

J Urol· February 2006

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Increased corpus cavernosum smooth muscle tone associated with partial bladder outlet obstruction is mediated via Rho-kinase.
Shaohua Chang, Joseph A Hypolite, Stephen A Zderic, Alan J Wein, Samuel Chacko

Am J Physiol Regul Integr Comp Physiol· October 2005

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Alteration of contractile and regulatory proteins following partial bladder outlet obstruction.
Samuel Chacko, Shaohua Chang, Joseph Hypolite, Michael Disanto, Alan Wein

Scand J Urol Nephrol Suppl· June 2005

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Regional alterations in the expression of smooth muscle myosin isoforms in response to partial bladder outlet obstruction.
Anita S Mannikarottu, Joseph A Hypolite, Stephen A Zderic, Alan J Wein, Samuel Chacko

J Urol· January 2005

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Diabetes induced decrease in detrusor smooth muscle force is associated with oxidative stress and overactivity of aldose reductase.
Arun K Changolkar, Joseph A Hypolite, Michael Disanto, Peter J Oates, Alan J Wein

J Urol· January 2005

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Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits.
Shaohua Chang, Joseph A Hypolite, Marielena Velez, Arun Changolkar, Alan J Wein

Am J Physiol Regul Integr Comp Physiol· October 2004

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Alteration in expression of myosin isoforms in detrusor smooth muscle following bladder outlet obstruction.
Michael E DiSanto, Raimund Stein, Shaohua Chang, Joseph A Hypolite, Yongmu Zheng

Am J Physiol Cell Physiol· December 2003

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Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase.
Wu Bing, Shaohua Chang, Joseph A Hypolite, Michael E DiSanto, Stephen A Zderic

Am J Physiol Renal Physiol· November 2003

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Enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction.
Shaohua Chang, Joseph A Hypolite, Stephen A Zderic, Alan J Wein, Samuel Chacko

J Urol· June 2002

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