Publications by authors named "Joseph Hyser"

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BTP2 restricts Tulane virus and human norovirus replication independent of store-operated calcium entry.
Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Jorge Villanueva, Joseph M Hyser

J Virol· June 2025

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The CRAC channel inhibitor BTP2 restricts Tulane virus and human norovirus replication independent of store-operated calcium entry.
Francesca J Scribano, J Thomas Gebert, Kristen A Engevik, Nicole M Hayes, Son Pham, Joseph M Hyser

bioRxiv· February 2025

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Viroporin activity is necessary for intercellular calcium signals that contribute to viral pathogenesis.
J Thomas Gebert, Francesca J Scribano, Kristen A Engevik, Ethan M Huleatt, Michael R Eledge, Joseph M Hyser

Sci Adv· January 2025

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Viroporin activity from rotavirus nonstructural protein 4 induces intercellular calcium waves that contribute to pathogenesis.
J Thomas Gebert, Francesca J Scribano, Kristen A Engevik, Asha A Philip, Takahiro Kawagishi, Joseph M Hyser

bioRxiv· May 2024

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Purinergic Signaling Drives Multiple Aspects of Rotavirus Pathophysiology.
Kristen A Engevik, Francesca J Scribano, J Thomas Gebert, Joseph M Hyser

bioRxiv· May 2024

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Distribution of P2Y and P2X purinergic receptor expression within the intestine.
Kristen A Engevik, Francesca J Scribano, J Thomas Gebert, Jacob L Perry, Sue E Crawford, Joseph M Hyser

Am J Physiol Gastrointest Liver Physiol· February 2024

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Host IPR channels are dispensable for rotavirus Ca signaling but critical for intercellular Ca waves that prime uninfected cells for rapid virus spread.
Jacob L Perry, Francesca J Scribano, John T Gebert, Kristen A Engevik, Jenna M Ellis, Joseph M Hyser

mBio· January 2024

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Live-Cell Fluorescence Imaging for Virus-Host Interactions.
Francesca J Scribano, Kristen A Engevik, J Thomas Gebert, Joseph M Hyser

Methods Mol Biol· January 2024

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Live Calcium Imaging of Virus-Infected Human Intestinal Organoid Monolayers Using Genetically Encoded Calcium Indicators.
J Thomas Gebert, Francesca J Scribano, Kristen A Engevik, Joseph M Hyser

J Vis Exp· January 2024

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The Inositol Trisphosphate Receptor (IP R) is Dispensable for Rotavirus-induced Ca Signaling and Replication but Critical for Paracrine Ca Signals that Prime Uninfected Cells for Rapid Virus Spread.
Jacob L Perry, Francesca J Scribano, John T Gebert, Kristen A Engevik, Jenna M Ellis, Joseph M Hyser

bioRxiv· August 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Joseph Hyser

mSphere· April 2023

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Acute high-fat diet impairs macrophage-supported intestinal damage resolution.
Andrea A Hill, Myunghoo Kim, Daniel F Zegarra-Ruiz, Lin-Chun Chang, Kendra Norwood, Joseph M Hyser

JCI Insight· February 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Joseph Hyser

J Virol· February 2023

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Virology under the Microscope-a Call for Rational Discourse.
Felicia Goodrum, Anice C Lowen, Seema Lakdawala, James Alwine, Arturo Casadevall, Joseph Hyser

mBio· February 2023

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Gastrointestinal organoids in the study of viral infections.
J Thomas Gebert, Francesca Scribano, Kristen A Engevik, Jacob L Perry, Joseph M Hyser

Am J Physiol Gastrointest Liver Physiol· January 2023

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A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis.
Yuqing Wang, Duolong Zhu, Laura C Ortiz-Velez, Jacob L Perry, Michael W Pennington, Joseph M Hyser

Proc Natl Acad Sci U S A· January 2023

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Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut-Brain Axis.
Melinda A Engevik, Berkley Luck, Chonnikant Visuthranukul, Faith D Ihekweazu, Amy C Engevik, Joseph M Hyser

Cell Mol Gastroenterol Hepatol· December 2021

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-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation.
Melinda A Engevik, Beatrice Herrmann, Wenly Ruan, Amy C Engevik, Kristen A Engevik, Joseph M Hyser

Gut Microbes· November 2021

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p38 MAPK Activity Is Required to Prevent Hyperactivation of NLRP3 Inflammasome.
Jin Na Shin, Lang Rao, Youbao Sha, Elmoataz Abdel Fattah, Joseph Hyser

J Immunol· July 2021

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Mucin-Degrading Microbes Release Monosaccharides That Chemoattract and Facilitate Colonization of the Human Intestinal Mucus Layer.
Melinda A Engevik, Amy C Engevik, Kristen A Engevik, Jennifer M Auchtung, Alexandra L Chang-Graham, Joseph M Hyser

ACS Infect Dis· May 2021

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Bacteroides ovatus Promotes IL-22 Production and Reduces Trinitrobenzene Sulfonic Acid-Driven Colonic Inflammation.
Faith D Ihekweazu, Melinda A Engevik, Wenly Ruan, Zhongcheng Shi, Robert Fultz, Joseph M Hyser

Am J Pathol· April 2021

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Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation.
Melinda A Engevik, Heather A Danhof, Wenly Ruan, Amy C Engevik, Alexandra L Chang-Graham, Joseph M Hyser

mBio· March 2021

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Reuterin disrupts metabolism and pathogenicity through reactive oxygen species generation.
Melinda A Engevik, Heather A Danhof, Ritu Shrestha, Alexandra L Chang-Graham, Joseph M Hyser

Gut Microbes· November 2020

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Rotavirus induces intercellular calcium waves through ADP signaling.
Alexandra L Chang-Graham, Jacob L Perry, Melinda A Engevik, Kristen A Engevik, Francesca J Scribano, Joseph M Hyser

Science· November 2020

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Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection.
Anubama Rajan, Matthew J Robertson, Hannah E Carter, Nina M Poole, Justin R Clark, Joseph M Hyser

PLoS Pathog· September 2020

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