Publications by authors named "Joseph L Johnson"

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Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents.
Lucas N Solano, Grady L Nelson, Conor T Ronayne, Shirisha Jonnalagadda, Sravan K Jonnalagadda, Joseph L Johnson

Sci Rep· October 2020

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Decarbamoylation of acetylcholinesterases is markedly slowed as carbamoyl groups increase in size.
Kunisi S Venkatasubban, Joseph L Johnson, Jamie L Thomas, Abdul Fauq, Bernadette Cusack

Arch Biochem Biophys· October 2018

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Synthesis and Evaluation of Baylis-Hillman Reaction Derived Imidazole and Triazole Cinnamates as Antifungal Agents.
Grady L Nelson, Michael J Williams, Shirisha Jonnalagadda, Mohammad A Alam, Gautam Mereddy, Joseph L Johnson

Int J Med Chem· October 2018

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Application of a Bioinformatics-Based Approach to Identify Novel Putative in vivo BACE1 Substrates.
Joseph L Johnson, Emily Chambers, Keerthi Jayasundera

Biomed Eng Comput Biol· October 2014

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Stereoselective synthesis of pyroglutamate natural product analogs from α- aminoacids and their anti-cancer evaluation.
Srinivas Tekkam, Mohammad A Alam, Matthew J Just, Steven M Berry, Joseph L Johnson

Anticancer Agents Med Chem· December 2013

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Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase.
Jeffrey T Auletta, Joseph L Johnson, Terrone L Rosenberry

Chem Biol Interact· September 2010

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Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.
Terrone L Rosenberry, Leilani K Sonoda, Sarah E Dekat, Bernadette Cusack, Joseph L Johnson

Biochemistry· December 2008

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Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis.
Terrone L Rosenberry, Leilani K Sonoda, Sarah E Dekat, Bernadette Cusack, Joseph L Johnson

Chem Biol Interact· September 2008

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Clinical heterogeneity of the LRRK2 G2019S mutation.
Spiridon Papapetropoulos, Carlos Singer, Owen A Ross, Mathias Toft, Joseph L Johnson

Arch Neurol· September 2006

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Evidence for a synergistic salt-protein interaction -- complex patterns of activation vs. inhibition of nitrogenase by salt.
Phillip E Wilson, Andrew C Nyborg, Jason Kenealey, Thomas J Lowery, Kyrsten Crawford, Joseph L Johnson

Biophys Chem· August 2006

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Lrrk2 and Lewy body disease.
Owen A Ross, Mathias Toft, Andrew J Whittle, Joseph L Johnson, Spiridon Papapetropoulos

Ann Neurol· February 2006

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Interactions between the peripheral site and the acylation site in acetylcholinesterase.
Terrone L Rosenberry, Joseph L Johnson, Bernadette Cusack, Jamie L Thomas, Sujata Emani

Chem Biol Interact· December 2005

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A novel strategy for protection against organophosphate toxicity: Evolution of cyclic inhibitors with high affinity for the acetylcholinesterase peripheral site.
Bernadette Cusack, Peteris Romanovskis, Joseph L Johnson, Gathline Etienne, Terrone L Rosenberry

Chem Biol Interact· December 2005

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Measuring carbamoylation and decarbamoylation rate constants by continuous assay of AChE.
Joseph L Johnson, Jamie L Thomas, Sujata Emani, Bernadette Cusack, Terrone L Rosenberry

Chem Biol Interact· December 2005

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Steric effects in the decarbamoylation of carbamoylated acetylcholinesterases.
Kunisi S Venkatasubban, Joseph L Johnson, Jamie L Thomas, Abdul Fauq, Bernadette Cusack

Chem Biol Interact· December 2005

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Inhibitors tethered near the acetylcholinesterase active site serve as molecular rulers of the peripheral and acylation sites.
Joseph L Johnson, Bernadette Cusack, Thomas F Hughes, Elizabeth H McCullough, Abdul Fauq

J Biol Chem· October 2003

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Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.
Joseph L Johnson, Bernadette Cusack, Matthew P Davies, Abdul Fauq, Terrone L Rosenberry

Biochemistry· May 2003

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