Publications by authors named "Joseph Larner"

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Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls.
Douglas Heimark, Jan McAllister, Joseph Larner

Endocr J· November 2014

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D-chiro-inositol glycan stimulates insulin secretion in pancreatic β cells.
Roman Lazarenko, Jessica Geisler, Douglas Bayliss, Joseph Larner, Chien Li

Mol Cell Endocrinol· April 2014

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Inositol, glycogen, insulin, and six nobelists.
Joseph Larner

J Biol Chem· April 2013

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Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aβ oligomers by insulin mimetic chiro-inositols.
Jason Pitt, Michael Thorner, David Brautigan, Joseph Larner, William L Klein

FASEB J· January 2013

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D-chiro-inositol glycans in insulin signaling and insulin resistance.
Joseph Larner, David L Brautigan, Michael O Thorner

Mol Med· February 2011

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Synthesis of C-glycoside analogues of beta-galactosamine-(1-->4)-3-O-methyl-D-chiro-inositol and assay as activator of protein phosphatases PDHP and PP2Calpha.
Sunej K Hans, Fatoumata Camara, Ahmad Altiti, Alejandro Martín-Montalvo, David L Brautigan, Joseph Larner

Bioorg Med Chem· February 2010

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Isolation, structure, synthesis, and bioactivity of a novel putative insulin mediator. A galactosamine chiro-inositol pseudo-disaccharide Mn2+ chelate with insulin-like activity.
Joseph Larner, John D Price, Douglas Heimark, Leigh Smith, Gordon Rule

J Med Chem· July 2003

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Fasting decreases the content of D-chiroinositol in human skeletal muscle.
Pavel N Shashkin, Laura C Huang, Joseph Larner, George E Vandenhoff, Abram Katz

Int J Exp Diabetes Res· April 2003

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How I became a biochemical pharmacologist.
Joseph Larner

IUBMB Life· February 2003

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D-chiro-inositol--its functional role in insulin action and its deficit in insulin resistance.
Joseph Larner

Int J Exp Diabetes Res· September 2002

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Both myo-inositol to chiro-inositol epimerase activities and chiro-inositol to myo-inositol ratios are decreased in tissues of GK type 2 diabetic rats compared to Wistar controls.
Tie-hua Sun, Douglas B Heimark, Thang Nguygen, Jerry L Nadler, Joseph Larner

Biochem Biophys Res Commun· May 2002

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