Publications by authors named "Joseph Lotem"

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Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development.
Kira Orlovsky, Elena Appel, Shay Hantisteanu, Tsviya Olender, Joseph Lotem

PLoS Genet· December 2024

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Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes.
Shay Hantisteanu, Yosef Dicken, Varda Negreanu, Dalia Goldenberg, Ori Brenner, Joseph Lotem

PLoS One· July 2020

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The Leo Sachs' legacy: a pioneer's journey through hematopoiesis.
Joseph Lotem, Yoram Groner

Int J Dev Biol· June 2018

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Runx3 in Immunity, Inflammation and Cancer.
Joseph Lotem, Ditsa Levanon, Varda Negreanu, Omri Bauer, Shay Hantisteanu

Adv Exp Med Biol· September 2017

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Runx3 at the interface of immunity, inflammation and cancer.
Joseph Lotem, Ditsa Levanon, Varda Negreanu, Omri Bauer, Shay Hantisteanu

Biochim Biophys Acta· April 2015

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Carcinogen-induced skin tumor development requires leukocytic expression of the transcription factor Runx3.
Omri Bauer, Shay Hantisteanu, Joseph Lotem, Yoram Groner

Cancer Prev Res (Phila)· September 2014

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Runx3-mediated transcriptional program in cytotoxic lymphocytes.
Joseph Lotem, Ditsa Levanon, Varda Negreanu, Dena Leshkowitz, Gilgi Friedlander

PLoS One· July 2014

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Transcription factor Runx3 regulates interleukin-15-dependent natural killer cell activation.
Ditsa Levanon, Varda Negreanu, Joseph Lotem, Karen Rae Bone, Ori Brenner

Mol Cell Biol· March 2014

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Cell-autonomous function of Runx1 transcriptionally regulates mouse megakaryocytic maturation.
Niv Pencovich, Ram Jaschek, Joseph Dicken, Ayelet Amit, Joseph Lotem

PLoS One· January 2014

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Addiction of t(8;21) and inv(16) acute myeloid leukemia to native RUNX1.
Oren Ben-Ami, Dan Friedman, Dena Leshkowitz, Dalia Goldenberg, Kira Orlovsky, Joseph Lotem

Cell Rep· September 2013

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Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function.
Ditsa Levanon, Yael Bernstein, Varda Negreanu, Karen Rae Bone, Amir Pozner, Joseph Lotem

EMBO Mol Med· October 2011

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A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis.
Oren Ben-Ami, Niv Pencovich, Joseph Lotem, Ditsa Levanon, Yoram Groner

Proc Natl Acad Sci U S A· January 2009

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Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs.
Fernando Cruz-Guilloty, Matthew E Pipkin, Ivana M Djuretic, Ditsa Levanon, Joseph Lotem

J Exp Med· January 2009

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Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles.
Jacob Bock Axelsen, Joseph Lotem, Leo Sachs, Eytan Domany

Proc Natl Acad Sci U S A· August 2007

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Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis.
Amir Pozner, Joseph Lotem, Cuiying Xiao, Dalia Goldenberg, Ori Brenner

BMC Dev Biol· July 2007

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Human cancers overexpress genes that are specific to a variety of normal human tissues.
Joseph Lotem, Dvir Netanely, Eytan Domany, Leo Sachs

Proc Natl Acad Sci U S A· December 2005

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Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.
Peter Tsvetkov, Gad Asher, Veronica Reiss, Yosef Shaul, Leo Sachs, Joseph Lotem

Proc Natl Acad Sci U S A· April 2005

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Induction in myeloid leukemic cells of genes that are expressed in different normal tissues.
Joseph Lotem, Hila Benjamin, Dvir Netanely, Eytan Domany, Leo Sachs

Proc Natl Acad Sci U S A· November 2004

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Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3.
Ditsa Levanon, Gustavo Glusman, David Bettoun, Edna Ben-Asher, Varda Negreanu, Joseph Lotem

Blood Cells Mol Dis· August 2004

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p53-dependent apoptosis and NAD(P)H:quinone oxidoreductase 1.
Gad Asher, Joseph Lotem, Leo Sachs, Yosef Shaul

Methods Enzymol· April 2004

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Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation.
Ofer Fainaru, Eilon Woolf, Joseph Lotem, Merav Yarmus, Ori Brenner

EMBO J· February 2004

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P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1.
Gad Asher, Joseph Lotem, Peter Tsvetkov, Veronica Reiss, Leo Sachs

Proc Natl Acad Sci U S A· December 2003

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.
Eilon Woolf, Cuiying Xiao, Ofer Fainaru, Joseph Lotem, Dalia Rosen

Proc Natl Acad Sci U S A· June 2003

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Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes.
Joseph Lotem, Hilah Gal, Rachel Kama, Ninette Amariglio, Gideon Rechavi

Proc Natl Acad Sci U S A· May 2003

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Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.
Gad Asher, Joseph Lotem, Leo Sachs, Chaim Kahana, Yosef Shaul

Proc Natl Acad Sci U S A· October 2002

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