Publications by authors named "Joseph P Garay"

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Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA.
Joseph P Garay, Rebecca Smith, Kaylyn Devlin, Daniel P Hollern, Tiera Liby

Breast Cancer Res· August 2021

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MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data.
Siyao Liu, Aatish Thennavan, Joseph P Garay, J S Marron, Charles M Perou

Genome Biol· August 2021

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CRISPR-based knock-in mutagenesis of the pioneer transcription factor FOXA1: optimization of strategies for multi-allelic proteins in cancer cells.
Shen Li, Joseph P Garay, Colby A Tubbs, Hector L Franco

FEBS Open Bio· June 2021

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FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease.
Susana Garcia-Recio, Aatish Thennavan, Michael P East, Joel S Parker, Juan M Cejalvo, Joseph P Garay

J Clin Invest· September 2020

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B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer.
Daniel P Hollern, Nuo Xu, Aatish Thennavan, Cherise Glodowski, Susana Garcia-Recio, Joseph P Garay

Cell· November 2019

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Ki-67 is required for maintenance of cancer stem cells but not cell proliferation.
Justin Cidado, Hong Yuen Wong, D Marc Rosen, Ashley Cimino-Mathews, Joseph P Garay

Oncotarget· February 2016

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TMSB4Y is a candidate tumor suppressor on the Y chromosome and is deleted in male breast cancer.
Hong Yuen Wong, Grace M Wang, Sarah Croessmann, Daniel J Zabransky, David Chu, Joseph P Garay

Oncotarget· December 2015

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MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers.
Morassa Mohseni, Justin Cidado, Sarah Croessmann, Karen Cravero, Ashley Cimino-Mathews, Joseph P Garay

Proc Natl Acad Sci U S A· December 2014

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Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
Grace M Wang, Hong Yuen Wong, Hiroyuki Konishi, Brian G Blair, Abde M Abukhdeir, Joseph P Garay

Cancer Res· June 2013

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Androgen receptor as a targeted therapy for breast cancer.
Joseph P Garay, Ben H Park

Am J Cancer Res· October 2012

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Omics and therapy - a basis for precision medicine.
Joseph P Garay, Joe W Gray

Mol Oncol· April 2012

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The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation.
Joseph P Garay, Bedri Karakas, Abde M Abukhdeir, David P Cosgrove, John P Gustin

Breast Cancer Res· February 2012

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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells.
Hiroyuki Konishi, Morassa Mohseni, Akina Tamaki, Joseph P Garay, Sarah Croessmann

Proc Natl Acad Sci U S A· October 2011

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PIK3CA mutations and EGFR overexpression predict for lithium sensitivity in human breast epithelial cells.
Michaela J Higgins, Julia A Beaver, Hong Yuen Wong, John P Gustin, Josh D Lauring, Joseph P Garay

Cancer Biol Ther· February 2011

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Knockin of mutant PIK3CA activates multiple oncogenic pathways.
John P Gustin, Bedri Karakas, Michele B Weiss, Abde M Abukhdeir, Josh Lauring, Joseph P Garay

Proc Natl Acad Sci U S A· February 2009

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A PCR-based high-throughput screen with multiround sample pooling: application to somatic cell gene targeting.
Hiroyuki Konishi, Josh Lauring, Joseph P Garay, Bedri Karakas, Abde M Abukhdeir

Nat Protoc· February 2008

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The multiple myeloma associated MMSET gene contributes to cellular adhesion, clonogenic growth, and tumorigenicity.
Josh Lauring, Abde M Abukhdeir, Hiroyuki Konishi, Joseph P Garay, John P Gustin

Blood· January 2008

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Tamoxifen-stimulated growth of breast cancer due to p21 loss.
Abde M Abukhdeir, Michele I Vitolo, Pedram Argani, Angelo M De Marzo, Bedri Karakas, Joseph P Garay

Proc Natl Acad Sci U S A· January 2008

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Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.
Hiroyuki Konishi, Bedri Karakas, Abde M Abukhdeir, Josh Lauring, John P Gustin, Joseph P Garay

Cancer Res· September 2007

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