Publications by authors named "Joseph Rathkey"

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Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study.
Chiraag Kulkarni, George Cholankeril, Touran Fardeen, Joseph Rathkey, Samir Khan

Clin Transl Gastroenterol· April 2025

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N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis.
Mausita Karmakar, Martin Minns, Elyse N Greenberg, Jose Diaz-Aponte, Kersi Pestonjamasp, Joseph K Rathkey

Nat Commun· May 2020

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Human polymorphisms in GSDMD alter the inflammatory response.
Joseph K Rathkey, Tsan S Xiao, Derek W Abbott

J Biol Chem· March 2020

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Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.
Joseph K Rathkey, Junjie Zhao, Zhonghua Liu, Yinghua Chen, Jie Yang

Sci Immunol· August 2018

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Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity.
Steven M Chirieleison, Joseph K Rathkey, Derek W Abbott

Sci Signal· July 2018

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Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
Jie Yang, Zhonghua Liu, Chuanping Wang, Rui Yang, Joseph K Rathkey

Proc Natl Acad Sci U S A· June 2018

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Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
Zhonghua Liu, Chuanping Wang, Joseph K Rathkey, Jie Yang, George R Dubyak

Structure· May 2018

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Live-cell visualization of gasdermin D-driven pyroptotic cell death.
Joseph K Rathkey, Bryan L Benson, Steven M Chirieleison, Jie Yang, Tsan S Xiao

J Biol Chem· September 2017

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Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease.
Steven M Chirieleison, Rebecca A Marsh, Prathna Kumar, Joseph K Rathkey, George R Dubyak

J Biol Chem· June 2017

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People choose to run at their optimal speed.
Joseph K Rathkey, Cara M Wall-Scheffler

Am J Phys Anthropol· May 2017

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Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.
Hana M Russo, Joseph Rathkey, Andrea Boyd-Tressler, Michael A Katsnelson, Derek W Abbott

J Immunol· August 2016

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