Publications by authors named "Joshua Bauer"

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Pharmacological Tools to Modulate Ordered Membrane Domains and Order-Dependent Protein Function.
Katherine M Stefanski, Hui Huang, Dustin D Luu, James M Hutchison, Nilabh Saksena, Joshua A Bauer

bioRxiv· October 2025

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High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants.
Katherine R Clowes Moster, Carlos G Vanoye, Ana C Chang-Gonzalez, Ian M Romaine, Katherine M Stefanski, Joshua A Bauer

bioRxiv· October 2025

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Multi-Ancestry Transcriptome-wide Association Studies Uncover New Insights into Breast Cancer Genetics and Biology.
Jie Ping, Guochong Jia, Qiuyin Cai, Xingyi Guo, Jifeng Wang, Joshua A Bauer

medRxiv· August 2025

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3D collagen high-throughput screen identifies drugs that induce epithelial polarity and enhance chemotherapy response in colorectal cancer.
Sarah J Harmych, Thomas P Hasaka, Chelsie K Sievers, Seung Woo Kang, Marisol A Ramirez, Joshua A Bauer

Commun Biol· August 2025

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Refining breast cancer genetic risk and biology through multi-ancestry fine-mapping analyses of 192 risk regions.
Guochong Jia, Zhishan Chen, Jie Ping, Qiuyin Cai, Ran Tao, Joshua A Bauer

Nat Genet· January 2025

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A High-Throughput Immune-Oncology Screen Identifies Immunostimulatory Properties of Cytotoxic Chemotherapy Agents in TNBC.
Kennady K Bullock, Thomas Hasaka, Emily Days, Joshua A Bauer, Patricia A Ward

Cancers (Basel)· December 2024

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Small-Molecule Modulators of Lipid Raft Stability and Protein-Raft Partitioning.
Katherine M Stefanski, Hui Huang, Dustin D Luu, James M Hutchison, Nilabh Saksena, Joshua A Bauer

bioRxiv· December 2024

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Discovery and Characterization of VU0542270, the First Selective Inhibitor of Vascular Kir6.1/SUR2B K Channels.
Kangjun Li, Samantha J McClenahan, Changho Han, Joseph D Bungard, Upendra Rathnayake, Joshua A Bauer

Mol Pharmacol· February 2024

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Dural composite hemangioendothelioma: The first intracranial case.
Alice Liu, Joshua S Bauer, Chun-Chieh Lin, Geoff Appelboom, George Zanazzi

Surg Neurol Int· February 2024

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An arrayed CRISPR knockout screen identifies genetic regulators of GLUT1 expression.
Yajuan Shi, Ketaki A Katdare, Hyosung Kim, Jonah C Rosch, Emma H Neal, Joshua A Bauer

Sci Rep· November 2023

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Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS.
Cayden J Dodd, Keagan S Chronister, Upendra Rathnayake, Lauren C Parr, Kangjun Li, Joshua A Bauer

Bioorg Med Chem Lett· May 2023

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Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen.
Aaron M Bender, Michael S Valentine, Joshua A Bauer, Emily Days, Craig W Lindsley

Assay Drug Dev Technol· April 2023

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A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Maximilian Lyon, Ping Li, Juan J Ferreira, Roman M Lazarenko, Sujay V Kharade, Joshua A Bauer

Proc Natl Acad Sci U S A· January 2023

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Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner.
Kevin P Kelly, Hugo Borsetti, Marta E Wenzler, Alessandro Ustione, Kwangho Kim, Joshua A Bauer

ACS Chem Biol· July 2022

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Combined Dusp4 and p53 loss with Dbf4 amplification drives tumorigenesis via cell cycle restriction and replication stress escape in breast cancer.
Ann Hanna, Mellissa J Nixon, M Valeria Estrada, Violeta Sanchez, Quanhu Sheng, Joshua Bauer

Breast Cancer Res· July 2022

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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.
Samantha J McClenahan, Caitlin N Kent, Sujay V Kharade, Elena Isaeva, Jade C Williams, Joshua A Bauer

Mol Pharmacol· May 2022

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Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma.
Kensey Bergdorf, Joshua A Bauer, David Westover, Courtney Phifer, Barbara Murphy

Cancers (Basel)· April 2022

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High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts.
Nico Fricke, Krishnan Raghunathan, Ajit Tiwari, Katherine M Stefanski, Muthuraj Balakrishnan, Joshua A Bauer

ACS Cent Sci· March 2022

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TBX1 functions as a putative oncogene of breast cancer through promoting cell cycle progression.
Shuya Huang, Xiang Shu, Jie Ping, Jie Wu, Jifeng Wang, Joshua A Bauer

Carcinogenesis· February 2022

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Functional Genomic Analyses of the 21q22.3 Locus Identifying Functional Variants and Candidate Gene for Breast Cancer Risk.
Chris Shidal, Xiang Shu, Jie Wu, Jifeng Wang, Shuya Huang, Joshua A Bauer

Cancers (Basel)· April 2021

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High-throughput drug screening of fine-needle aspiration-derived cancer organoids.
Kensey Bergdorf, Courtney Phifer, Vijaya Bharti, David Westover, Joshua Bauer

STAR Protoc· December 2020

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Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids.
Anna E Vilgelm, Kensey Bergdorf, Melissa Wolf, Vijaya Bharti, Rebecca Shattuck-Brandt, Joshua A Bauer

iScience· August 2020

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Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
Johanna M Schafer, Brian D Lehmann, Paula I Gonzalez-Ericsson, Clayton B Marshall, J Scott Beeler, Joshua A Bauer

Sci Transl Med· March 2020

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Novel three-dimensional cultures provide insights into thyroid cancer behavior.
Mason A Lee, Kensey N Bergdorf, Courtney J Phifer, Caroline Y Jones, Sonia Y Byon, Joshua A Bauer

Endocr Relat Cancer· February 2020

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Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5-MYC Protein-Protein Interaction.
Jonathan D Macdonald, Selena Chacón Simon, Changho Han, Feng Wang, J Grace Shaw, Joshua A Bauer

J Med Chem· December 2019

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