Publications by authors named "Joshua Donaldson"

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Highlights of FDA Oncology Approvals in 2023: Bispecific T-cell Engagers, Pediatric Indications, and Inclusive Drug Development.
Joshua M Donaldson, Marjilla Seddiq, Michael J Fusco, Shyamli Singla, Gulsum E Pamuk

Cancer Discov· December 2023

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PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model.
Karen Cravero, Morgan V Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, Joshua Donaldson

Oncotarget· September 2022

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Peripheral Blood Monocyte Abundance Predicts Outcomes in Patients with Breast Cancer.
Margaret L Axelrod, Yu Wang, Yaomin Xu, Xiaopeng Sun, Cosmin A Bejan, Joshua Donaldson

Cancer Res Commun· May 2022

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Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer.
Carmine De Angelis, Xiaoyong Fu, Maria Letizia Cataldo, Agostina Nardone, Resel Pereira, Joshua Donaldson

Clin Cancer Res· September 2021

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Correction: Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer.
Carmine De Angelis, Xiaoyong Fu, Maria Letizia Cataldo, Agostina Nardone, Resel Pereira, Joshua Donaldson

Clin Cancer Res· September 2021

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Hierarchical tumor heterogeneity mediated by cell contact between distinct genetic subclones.
Swathi Karthikeyan, Ian G Waters, Lauren Dennison, David Chu, Joshua Donaldson

J Clin Invest· March 2021

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Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer.
Margaret L Axelrod, Mellissa J Nixon, Paula I Gonzalez-Ericsson, Riley E Bergman, Mark A Pilkinton, Joshua Donaldson

Clin Cancer Res· November 2020

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The K666N mutation in SF3B1 is associated with increased progression of MDS and distinct RNA splicing.
W Brian Dalton, Eric Helmenstine, Lisa Pieterse, Bing Li, Christopher D Gocke, Joshua Donaldson

Blood Adv· April 2020

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Hotspot SF3B1 mutations induce metabolic reprogramming and vulnerability to serine deprivation.
W Brian Dalton, Eric Helmenstine, Noel Walsh, Lukasz P Gondek, Dhanashree S Kelkar, Joshua Donaldson

J Clin Invest· August 2019

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Circulating Tumor DNA: Measurement and Clinical Utility.
Joshua Donaldson, Ben Ho Park

Annu Rev Med· January 2018

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Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Joshua M Donaldson, Cindy Zer, Kendra N Avery, Krzysztof P Bzymek, David A Horne

Proc Natl Acad Sci U S A· October 2013

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Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies.
Joshua M Donaldson, Csaba Kari, Ruben C Fragoso, Ulrich Rodeck, John C Williams

Cancer Biol Ther· November 2009

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Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic mAbs C225 and 425.
Vishal Kamat, Joshua M Donaldson, Csaba Kari, Marlene R D Quadros, Peter I Lelkes

Cancer Biol Ther· May 2008

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