Publications by authors named "Joshua Hack"

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Stereotactic radiosurgery as adjuvant or salvage treatment for sporadic hemangioblastomas: A multi-center international study.
Salem M Tos, S Farzad Maroufi, Bardia Hajikarimloo, Ahmed Shaaban, Georgios Mantziaris, Joshua D Hack

J Neurol Sci· December 2025

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Longitudinal analyses of electronic medical records reveal dynamic developmental trajectories for patients with SCN8A-related disorders.
Kiran Smelser, Taryn Laird, Joshua B Hack, Elyse Tanzer, Ian Stewart

Epilepsia· December 2025

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Selecting effective antiseizure medications for early treatment of SCN8A-related epilepsy using a machine learning approach incorporating clinician and caregiver assessments.
Joshua B Hack, Michael F Hammer

Epilepsia· October 2025

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A comparison of outcomes after radiosurgery in non-small cell lung cancer patients with one versus more than twenty brain metastases: an international multi-center study.
Chris Z Wei, Regan Shanahan, David Puccio, Hansen Deng, Cheng-Chia Lee, Joshua D Hack

J Neurooncol· September 2025

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Gene Specific Pathogenicity Predictor for Chromatin-Remodeling BAF Complex-Associated Neurodevelopmental Disorders.
Joshua Hack, Mohammad Nazim

bioRxiv· September 2025

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Outcomes After Stereotactic Radiosurgery for Intracranial Hemangioblastoma in Von Hippel-Lindau Disease and Sporadic Cases: An International Multicenter Study.
Ahmed Shaaban, Salem M Tos, Georgios Mantziaris, Duy Pham, Sam Dayawansa, Joshua D Hack

Neurosurgery· June 2025

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Patients carrying pathogenic SCN8A variants with loss- and gain-of-function effects can be classified into five subgroups exhibiting varying developmental and epileptic components of encephalopathy.
Joshua B Hack, Joseph C Watkins, John M Schreiber, Michael F Hammer

Epilepsia· November 2024

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Machine learning models reveal distinct disease subgroups and improve diagnostic and prognostic accuracy for individuals with pathogenic SCN8A gain-of-function variants.
Joshua B Hack, Joseph C Watkins, Michael F Hammer

Biol Open· April 2024

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Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy.
Michael F Hammer, Collin T Krzyzaniak, Erfan Bahramnejad, Kiran J Smelser, Joshua B Hack

Clin Sci (Lond)· February 2024

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Clinical severity is correlated with age at seizure onset and biophysical properties of recurrent gain of function variants associated with SCN8A-related epilepsy.
Kyung Mi Chung, Joshua Hack, Jennifer Andrews, Maureen Galindo-Kelly, John Schreiber

Epilepsia· December 2023

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The International SCN8A Patient Registry: A Scientific Resource to Advance the Understanding and Treatment of a Rare Pediatric Neurodevelopmental Syndrome.
Jennifer G Andrews, Maureen Kelly Galindo, Joshua B Hack, Joseph C Watkins, Gabrielle A Conecker

J Registry Manag· August 2023

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Distinguishing Loss-of-Function and Gain-of-Function Variants Using a Random Forest Classification Model Trained on Clinical Features.
Joshua B Hack, Kyle Horning, Denise M Juroske Short, John M Schreiber, Joseph C Watkins

Neurol Genet· June 2023

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Quantifying endodermal strains during heart tube formation in the developing chicken embryo.
Joshua M Hack, Nareen Z Anwar, John G Jackson, Meagan E Furth, Victor D Varner

J Biomech· March 2023

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Clinical and radiologic outcomes after stereotactic radiosurgery for meningiomas in direct contact with the optic apparatus: an international multicenter study.
David T Asuzu, Adomas Bunevicius, Rithika Kormath Anand, Mohanad Suleiman, Ahmed M Nabeel, Joshua D Hack

J Neurosurg· April 2022

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Dose to neuroanatomical structures surrounding pituitary adenomas and the effect of stereotactic radiosurgery on neuroendocrine function: an international multicenter study.
I Jonathan Pomeraniec, Zhiyuan Xu, Cheng-Chia Lee, Huai-Che Yang, Tomas Chytka, Joshua Hack

J Neurosurg· March 2022

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Stereotactic radiosurgery for clinoid meningiomas: a multi-institutional study.
Adomas Bunevicius, Stylianos Pikis, Rithika Kormath Anand, Ahmed M Nabeel, Wael A Reda, Joshua D Hack

Acta Neurochir (Wien)· October 2021

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Dose homogeneity analysis of adjuvant radiation treatment in surgically resected brain metastases: Comparison of IORT, SRS, and IMRT indices.
Basem A Dahshan, Joshua S Weir, Robert P Bice, Paul Renz, Daniel T Cifarelli, Joshua Hack

Brachytherapy· August 2021

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Stereotactic Radiosurgery for Perioptic Meningiomas: An International, Multicenter Study.
Adomas Bunevicius, Rithika Kormath Anand, Mohanad Suleiman, Ahmed M Nabeel, Wael A Reda, Joshua D Hack

Neurosurgery· March 2021

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ECM Stiffness Controls the Activation and Contractility of Corneal Keratocytes in Response to TGF-β1.
Daniel P Maruri, Miguel Miron-Mendoza, Pouriska B Kivanany, Joshua M Hack, David W Schmidtke

Biophys J· November 2020

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Tumor Cavity Recurrence after Stereotactic Radiosurgery of Surgically Resected Brain Metastases: Implication of Deviations from Contouring Guidelines.
David M McDermott, Joshua D Hack, Christoper P Cifarelli, John A Vargo

Stereotact Funct Neurosurg· February 2020

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Intraoperative radiotherapy (IORT) for surgically resected brain metastases: outcome analysis of an international cooperative study.
Christopher P Cifarelli, Stefanie Brehmer, John Austin Vargo, Joshua D Hack, Klaus Henning Kahl

J Neurooncol· November 2019

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Feasibility of dose escalation using intraoperative radiotherapy following resection of large brain metastases compared to post-operative stereotactic radiosurgery.
John A Vargo, Kristie M Sparks, Rahul Singh, Geraldine M Jacobson, Joshua D Hack

J Neurooncol· November 2018

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Gamma Knife Radiosurgery for Arteriovenous Malformations Using a Four-Dimensional Dynamic Volume Computed Tomography Angiography Planning System as an Alternative to Traditional Catheter Angiogram.
Christopher P Cifarelli, John A Vargo, Todd Tenenholz, Joshua D Hack, Grenaville Guthrie

Cureus· June 2018

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Efficacy of Stereotactic Radiosurgery in Patients with Multiple Metastases: Importance of Volume Rather Than Number of Lesions.
Basem A Dahshan, Malcolm D Mattes, Sanjay Bhatia, Mary Susan Palek, Christopher P Cifarelli, Joshua D Hack

Cureus· December 2017

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Stereotactic Radiosurgery for Brainstem Metastases: An International Cooperative Study to Define Response and Toxicity.
Daniel M Trifiletti, Cheng-Chia Lee, Hideyuki Kano, Jonathan Cohen, James Janopaul-Naylor, Joshua D Hack

Int J Radiat Oncol Biol Phys· October 2016

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