Publications by authors named "Joshua Knowles"

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Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial.
Frederick J Raal, Jean Bergeron, Daniel Gaudet, Robert S Rosenson, David R Sullivan, Joshua W Knowles

Lancet Diabetes Endocrinol· December 2025

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Lipoprotein(a) and recurrent atherosclerotic cardiovascular events: the US Family Heart Database.
Diane E MacDougall, Anne Tybjærg-Hansen, Joshua W Knowles, Theresa P Stern, Bonnie K Hartsuff

Eur Heart J· November 2025

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Improving Options and Access for People With a Substance Use Disorder: A Service Evaluation of a Novel Nurse Practitioner-Led Ambulatory Model of Care for Withdrawal Management.
Carol Reid, Jeanine Young, Darren Smyth, Adam Searby, Mary Fenech, Joshua Knowles

Drug Alcohol Rev· November 2025

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Cardiac Allograft Vasculopathy Inhibition with Alirocumab: The CAVIAR Trial.
William F Fearon, Kosei Terada, Kuniaki Takahashi, Annette Skoda, Helen I Luikart, Joshua W Knowles

Circulation· November 2025

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Changes in Apolipoprotein A1-Associated Proteomic Composition After Pioglitazone Treatment Versus Weight Loss.
Shyon Parsa, Timothy S Collier, Michael J McPhaul, Olle Melander, Joshua W Knowles

Int J Mol Sci· November 2025

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Electronic health records-based algorithms to screen for U.S. Centers for Disease Control and Prevention tier 1 genetic diseases: a scoping review.
William R Harris, Marianna S Hernandez, Khanh N H Ngo, Anne Fladger, Charles A Brunette, Joshua W Knowles

J Am Med Inform Assoc· October 2025

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The functional landscape of coding variation in the familial hypercholesterolemia gene .
Daniel R Tabet, Atina G Coté, Megan C Lancaster, Jochen Weile, Ashyad Rayhan, Joshua W Knowles

Science· October 2025

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Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations.
Pik Fang Kho, Neil Wary, Daniela Zanetti, Fahim Abbasi, Joshua W Knowles

Metabolism· August 2025

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Cardiologists' Perceptions of Cardiogenetic Testing and Management.
W H Wilson Tang, Quan M Bui, Allison L Cirino, Lisa Dellefave-Castillo, Brendan J Floyd, Joshua W Knowles

JACC Adv· August 2025

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Successful Rituximab Treatment of GPIHBP1 Autoantibody-Associated Hypertriglyceridemia.
Tasmeen Hussain, Audra Horomanski, Sneha Jain, Cindy Lamendola, Fahim Abbasi, Joshua W Knowles

JACC Case Rep· August 2025

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A functional genomic framework to elucidate novel causal metabolic dysfunction-associated fatty liver disease genes.
Peter Saliba-Gustafsson, Johanne M Justesen, Amanda Ranta, Disha Sharma, Ewa Bielczyk-Maczynska, Joshua W Knowles

Hepatology· July 2025

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Label-Free Detection of Lipid Accumulation in Cells Using Magnetic Levitation.
Kazim Kerim Moncal, Laeya Abdoli Najmi, Rakhi Gupta, Malavika Ramarao, Joshua W Knowles

Adv Biol (Weinh)· July 2025

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Genetics of growth rate in induced pluripotent stem cells.
Brian N Lee, Henry J Taylor, Filippo Cipriani, Narisu Narisu, Catherine C Robertson, Joshua W Knowles

bioRxiv· July 2025

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Primary care providers' perspectives on receiving opportunistic genomic results from a national study: The Million Veteran Program Return Of Actionable Results (MVP-ROAR) Study.
Anna L Johannsen, Morgan E Danowski, Kailyn E Sitter, Charlene L Preys, Haley L Gerety, Joshua W Knowles

Genet Med· June 2025

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Many Journeys Originating at the Same Source to Arrive at Solutions to the Common Problem of High Lipoprotein(a).
Jean Woody Luxama, Joshua W Knowles

Circ Genom Precis Med· April 2025

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Retrospective review of surgeon administered transversus abdominis plane blocks at emergency caesarean.
Rachel Einarsson, Joshua Knowles

Aust N Z J Obstet Gynaecol· February 2025

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Genetics of cardiometabolic disease progression.
Johanne M Justesen, Guhan Venkataraman, Yosuke Tanigawa, Ruilin Li, Trevor Hastie, Joshua W Knowles

medRxiv· February 2025

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Falls on an inpatient brain injury rehabilitation unit … What are the consequences?
Kathryn Marshall, Janelle Griffin, Joshua Knowles, Shannon Galletly, Freyr Patterson

Brain Impair· December 2024

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Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations.
Pik Fang Kho, Neil Wary, Daniela Zanetti, Fahim Abbasi, Joshua W Knowles

medRxiv· November 2024

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Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
Nadine Nagy, Kathryn S Czepiel, Gernot Kaber, Darko Stefanovski, Aviv Hargil, Joshua W Knowles

Cells· October 2024

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One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.
Daniel Seung Kim, Emily L Chu, Emily E Keamy-Minor, Ishan Dhananjay Paranjpe, Wilson L Tang, Joshua W Knowles

Front Cardiovasc Med· August 2024

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X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction.
Peixiang Zhang, Joseph J Munier, Carrie B Wiese, Laurent Vergnes, Jenny C Link, Joshua W Knowles

Nat Commun· July 2024

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Loss of reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes.
Grace Z Yu, Nicole A J Krentz, Liz Bentley, Meng Zhao, Keanu Paphiti, Joshua W Knowles

bioRxiv· July 2024

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Another Use for Polygenic Risk Scores: Improving Risk Prediction for Heterozygous Familial Hypercholesterolemia.
Brian T Palmisano, Joshua W Knowles

JACC Adv· November 2023

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