Publications by authors named "Joshua P Plotnik"

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Synthetic lethality of mRNA quality control complexes in cancer.
Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Joshua P Plotnik

Nature· February 2025

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MYC Family Amplification Dictates Sensitivity to BET Bromodomain Protein Inhibitor Mivebresib (ABBV075) in Small-Cell Lung Cancer.
Joshua P Plotnik, Zheng Zha, Weiguo Feng, Irene Lee, Jacob Riehm

Mol Cancer Res· August 2024

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Inhibition of MALT1 and BCL2 Induces Synergistic Antitumor Activity in Models of B-Cell Lymphoma.
Joshua P Plotnik, Adam E Richardson, Haopeng Yang, Estela Rojas, Velitchka Bontcheva

Mol Cancer Ther· July 2024

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Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Lu Zhang, Tianyu Cai, Xiaoyu Lin, Xiaoli Huang, Mai H Bui, Joshua P Plotnik

Mol Cancer Ther· October 2021

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Fighting PRC1 via the RING.
Joshua P Plotnik

Nat Chem Biol· July 2021

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Toll-like receptor 4 signaling activates ERG function in prostate cancer and provides a therapeutic target.
Benjamin M Greulich, Joshua P Plotnik, Travis J Jerde, Peter C Hollenhorst

NAR Cancer· March 2021

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Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Emily J Faivre, Keith F McDaniel, Daniel H Albert, Srinivasa R Mantena, Joshua P Plotnik

Nature· February 2020

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ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase.
Sunil Tomar, Joshua P Plotnik, James Haley, Joshua Scantland, Subramanyam Dasari

Cancer Lett· February 2018

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Genome-Wide Analysis of RAS/ERK Signaling Targets.
Joshua P Plotnik, Peter C Hollenhorst

Methods Mol Biol· January 2018

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Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.
Joshua P Plotnik, Peter C Hollenhorst

Nucleic Acids Res· May 2017

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An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer.
Vivekananda Kedage, Nagarathinam Selvaraj, Taylor R Nicholas, Justin A Budka, Joshua P Plotnik

Cell Rep· October 2016

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Extracellular signal-regulated kinase signaling regulates the opposing roles of JUN family transcription factors at ETS/AP-1 sites and in cell migration.
Nagarathinam Selvaraj, Justin A Budka, Mary W Ferris, Joshua P Plotnik, Peter C Hollenhorst

Mol Cell Biol· January 2015

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ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells.
Joshua P Plotnik, Justin A Budka, Mary W Ferris, Peter C Hollenhorst

Nucleic Acids Res· October 2014

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