Publications by authors named "Joshua Speed"

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Pharmacological inhibition of IL12β is effective in treating pressure overload-induced cardiac inflammation and heart failure.
Umesh Bhattarai, Xiaochen He, Ziru Niu, Lihong Pan, Dongzhi Wang, Joshua S Speed

Front Immunol· September 2025

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The impact of Asic2 deletion on metabolic homeostasis in mice.
Madison Hamby, Jasleen Kaur, Seth Lirette, Jussara M do Carmo, Joshua Speed

Physiol Rep· September 2025

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Genetic inhibition of IL-12β suppresses systolic overload-induced cardiac inflammation and heart failure development.
Umesh Bhattarai, Xiaochen He, Ziru Niu, Lihong Pan, Dongzhi Wang, Joshua S Speed

bioRxiv· September 2025

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Adipocyte-specific ET receptor overexpression induces obesity, insulin resistance, and dyslipidemia in high-fat diet-fed female mice.
Bridget D Konadu, Osvaldo Rivera-Gonzales, Natalie A Wilson, Madilyn Lewis, Hayley A Murphy, Joshua S Speed

Physiol Rep· September 2025

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Adipocyte endothelin B receptor activation inhibits adiponectin production and causes insulin resistance in obese mice.
Osvaldo Rivera-Gonzalez, Megumi F Mills, Bridget D Konadu, Natalie A Wilson, Hayley A Murphy, Joshua S Speed

Acta Physiol (Oxf)· October 2024

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Sexual Dimorphism's impact on adipogenesis: A three-dimensional in vitro model treated with 17β-estradiol and testosterone.
Pallabi Pal, Rodrigo O Maranon, Osvaldo J Rivera Gonzales, Joshua S Speed, Amol V Janorkar

Mol Cell Endocrinol· August 2024

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Influence of the Tissue Collection Procedure on the Adipogenic Differentiation of Human Stem Cells: Ischemic versus Well-Vascularized Adipose Tissue.
Pallabi Pal, Abelardo Medina, Sheetal Chowdhury, Courtney A Cates, Ratna Bollavarapu, Joshua S Speed

Biomedicines· May 2024

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Don't sweat the small stuff: skin mechanisms of sodium homeostasis and associations with long-term blood pressure.
Joshua S Speed, David M Pollock, John S Clemmer

Clin Sci (Lond)· May 2023

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Endothelin receptor antagonism improves glucose tolerance and adipose tissue inflammation in an experimental model of systemic lupus erythematosus.
Osvaldo Rivera-Gonzalez, Clinton T Case, Natalie A Wilson, Joshua S Speed, Erin B Taylor

Am J Physiol Endocrinol Metab· January 2023

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Endothelin antagonism reduces hemoglobin A1c in patients with pulmonary hypertension.
Jennifer R Stapel, Joshua S Speed, John S Clemmer

Can J Physiol Pharmacol· August 2022

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Short-term daytime restricted feeding in rats with high salt impairs diurnal variation of Na excretion.
Megan K Rhoads, Joshua S Speed, Kaehler J Roth, Dingguo Zhang, Chunhua Jin

Am J Physiol Renal Physiol· March 2022

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Acclimation to a High-Salt Diet Is Sex Dependent.
Eman Y Gohar, Carmen De Miguel, Ijeoma E Obi, Elizabeth M Daugherty, Kelly A Hyndman, Joshua S Speed

J Am Heart Assoc· March 2022

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Endothelin receptor antagonism improves glucose handling, dyslipidemia, and adipose tissue inflammation in obese mice.
Osvaldo Rivera-Gonzalez, Natalie A Wilson, Laura E Coats, Erin B Taylor, Joshua S Speed

Clin Sci (Lond)· July 2021

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Cardiovascular Risk Factors Following Vertical Sleeve Gastrectomy in Black Americans Compared with White Americans.
Joshua S Speed, William A Pruett, Seth T Lirette, Joseph J Cook, Charles L Phillips

Obes Surg· March 2021

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Endothelin-1 in the pathophysiology of obesity and insulin resistance.
Haley N Jenkins, Osvaldo Rivera-Gonzalez, Yann Gibert, Joshua S Speed

Obes Rev· December 2020

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RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines.
Jerry D Monroe, Satya A Moolani, Elvin N Irihamye, Joshua S Speed, Yann Gibert

Cells· December 2020

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Loss of endothelin type B receptor function improves insulin sensitivity in rats.
Osvaldo J Rivera-Gonzalez, Malgorzata Kasztan, Jermaine G Johnston, Kelly A Hyndman, Joshua S Speed

Can J Physiol Pharmacol· September 2020

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Fluid-electrolyte homeostasis requires histone deacetylase function.
Kelly A Hyndman, Joshua S Speed, Luciano D Mendoza, John M Allan, Jackson Colson

JCI Insight· August 2020

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Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion.
Jermaine G Johnston, Joshua S Speed, Bryan K Becker, Malgorzata Kasztan, Reham H Soliman

Hypertension· June 2020

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Loss of circadian gene in the collecting duct lowers blood pressure in male, but not female, mice.
Dingguo Zhang, Chunhua Jin, Ijeoma E Obi, Megan K Rhoads, Reham H Soliman, Joshua S Speed

Am J Physiol Renal Physiol· March 2020

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Elevated plasma endothelin-1 is associated with reduced weight loss post vertical sleeve gastrectomy.
Haley N Jenkins, London J Williams, Adam Dungey, Kenneth D Vick, Bernadette E Grayson, Joshua S Speed

Surg Obes Relat Dis· July 2019

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Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice.
Malgorzata Kasztan, Brandon M Fox, Jeffrey D Lebensburger, Kelly A Hyndman, Joshua S Speed

Blood Adv· May 2019

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Maternal separation enhances anticontractile perivascular adipose tissue function in male rats on a high-fat diet.
Analia S Loria, Frank T Spradley, Ijeoma E Obi, Bryan K Becker, Carmen De Miguel, Joshua S Speed

Am J Physiol Regul Integr Comp Physiol· December 2018

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Diurnal pattern in skin Na and water content is associated with salt-sensitive hypertension in ET receptor-deficient rats.
Joshua S Speed, Kelly A Hyndman, Malgorzata Kasztan, Jermaine G Johnston, Kaehler J Roth

Am J Physiol Regul Integr Comp Physiol· April 2018

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High dietary sodium causes dyssynchrony of the renal molecular clock in rats.
Joshua S Speed, Kelly A Hyndman, Kaehler Roth, Jonathan B Heimlich, Malgorzata Kasztan

Am J Physiol Renal Physiol· January 2018

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