Publications by authors named "Jozef Stec"

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Convenient synthesis and in vitro activity of oxalyl bis(benzenesulfonylhydrazides) and related compounds.
Jozef Stec, Shang Xie, Lena Alshukri, Gina J Kang, Paula K Hudson

Results Chem· January 2023

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Activity of (1-benzyl-4-triazolyl)-indole-2-carboxamides against Toxoplasma gondii and Cryptosporidium parvum.
Shahbaz M Khan, Anolan Garcia Hernandez, Idrees Mehraj Allaie, Gregory M Grooms, Kun Li, Jozef Stec

Int J Parasitol Drugs Drug Resist· August 2022

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Facile synthesis of the fungus-derived natural products: '-dipalmitoleyl urea (C) and '-dioleyl urea (C).
Jozef Stec, Stevan Pecic

Nat Prod Res· April 2022

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Benefits of delivering research podium presentations by students enrolled in pharmacy programs: A descriptive study.
Jozef Stec, Charitha Madiraju, Eva Y Wong, Ronny Priefer, Henry Hua

Curr Pharm Teach Learn· October 2021

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Analysis of Student Perceptions of Just-In-Time Teaching Pedagogy in PharmD Microbiology and Immunology Courses.
Charitha Madiraju, Eglis Tellez-Corrales, Henry Hua, Jozef Stec, Andromeda M Nauli

Front Immunol· March 2021

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Novel acyl carbamates and acyl / diacyl ureas show in vitro efficacy against Toxoplasma gondii and Cryptosporidium parvum.
Kun Li, Gregory M Grooms, Shahbaz M Khan, Anolan Garcia Hernandez, William H Witola, Jozef Stec

Int J Parasitol Drugs Drug Resist· December 2020

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Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist.
Suzanne G Mays, Józef Stec, Xu Liu, Emma H D'Agostino, Richard J Whitby

Sci Rep· December 2020

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The preclinical candidate indole-2-carboxamide improves immune responses to Mycobacterium tuberculosis infection in healthy subjects and individuals with type 2 diabetes.
Ruoqiong Cao, Hicret Islamoglu, Garrett Teskey, Karo Gyurjian, Rachel Abrahem, Jozef Stec

Int Microbiol· May 2020

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Synergistic Interactions of Indole-2-Carboxamides and β-Lactam Antibiotics against Mycobacterium abscessus.
Clément Raynaud, Wassim Daher, Françoise Roquet-Banères, Matt D Johansen, Jozef Stec

Antimicrob Agents Chemother· April 2020

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Advancing the Therapeutic Potential of Indoleamides for Tuberculosis.
Shichun Lun, Rokeya Tasneen, Tridib Chaira, Jozef Stec, Oluseye K Onajole

Antimicrob Agents Chemother· July 2019

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Controlling Extra- and Intramacrophagic by Targeting Mycolic Acid Transport.
Albertus Viljoen, Jean-Louis Herrmann, Oluseye K Onajole, Jozef Stec, Alan P Kozikowski

Front Cell Infect Microbiol· July 2018

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Structure and Dynamics of the Liver Receptor Homolog 1-PGC1 Complex.
Suzanne G Mays, C Denise Okafor, Micheal L Tuntland, Richard J Whitby, Venkatasubramanian Dharmarajan, Józef Stec

Mol Pharmacol· July 2017

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Targeting Mycolic Acid Transport by Indole-2-carboxamides for the Treatment of Mycobacterium abscessus Infections.
Alan P Kozikowski, Oluseye K Onajole, Jozef Stec, Christian Dupont, Albertus Viljoen

J Med Chem· July 2017

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Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists.
Suzanne G Mays, C Denise Okafor, Richard J Whitby, Devrishi Goswami, Józef Stec

J Biol Chem· December 2016

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Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection.
Jozef Stec, Oluseye K Onajole, Shichun Lun, Haidan Guo, Benjamin Merenbloom

J Med Chem· July 2016

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Recently disclosed chemical entities as potential candidates for management of tuberculosis.
Jozef Stec, Ehab A Abourashed

Pharm Pat Anal· April 2016

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Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis.
Jozef Stec, Catherine Vilchèze, Shichun Lun, Alexander L Perryman, Xin Wang

ChemMedChem· November 2014

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Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.
Gustavo A Afanador, Stephen P Muench, Martin McPhillie, Alina Fomovska, Arne Schön, Jozef Stec

Biochemistry· December 2013

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Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.
Jozef Stec, Alina Fomovska, Gustavo A Afanador, Stephen P Muench, Ying Zhou

ChemMedChem· July 2013

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Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.
Stephen P Muench, Jozef Stec, Ying Zhou, Gustavo A Afanador, Martin J McPhillie

Bioorg Med Chem Lett· June 2013

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Preliminary structure-activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.
Oluseye K Onajole, Marco Pieroni, Suresh K Tipparaju, Shichun Lun, Jozef Stec

J Med Chem· May 2013

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Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway.
Alina Fomovska, Qingqing Huang, Kamal El Bissati, Ernest J Mui, William H Witola, Jozef Stec

Antimicrob Agents Chemother· May 2012

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Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania.
Jozef Stec, Qingqing Huang, Marco Pieroni, Marcel Kaiser, Alina Fomovska

J Med Chem· April 2012

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The first total synthesis of (+)-mucosin.
Alan R Henderson, Jozef Stec, David R Owen, Richard J Whitby

Chem Commun (Camb)· April 2012

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Tandem insertion of halocarbenoids and lithium acetylides into zirconacycles: a novel rearrangement to zirconium alkenylidenates by β-addition to an alkynyl zirconocene.
Jozef Stec, Emma Thomas, Sally Dixon, Richard J Whitby

Chemistry· April 2011

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