Publications by authors named "Juan Flo"

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Development of bivalent RBD adapted COVID-19 vaccines for broad sarbecovirus immunity.
Laura A Bruno, Celeste Pueblas Castro, Agostina Demaría, Lineia Prado, Clara G Fascetto Cassero, Juan M Flo

NPJ Vaccines· May 2025

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Immunogenicity and safety of monovalent and bivalent SARS-CoV-2 variant adapted RBD-based protein booster vaccines in adults previously immunized with different vaccine platforms: A phase II/III, randomized clinical trial.
Gonzalo Perez Marc, Lorena M Coria, Ana Ceballos, Juan Manuel Rodriguez, Mónica E Lombardo, Florencia Cahn, Florencia Bues

Vaccine· April 2025

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A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.
Lorena M Coria, Juan Manuel Rodriguez, Agostina Demaria, Laura A Bruno, Mayra Rios Medrano, Juan M Flo

Nat Commun· February 2024

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Safety and immunogenicity of a SARS-CoV-2 Gamma variant RBD-based protein adjuvanted vaccine used as booster in healthy adults.
Karina A Pasquevich, Lorena M Coria, Ana Ceballos, Bianca Mazzitelli, Juan Manuel Rodriguez

Nat Commun· July 2023

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Immunomodulatory oligonucleotide IMT504: Effects on mesenchymal stem cells as a first-in-class immunoprotective/immunoregenerative therapy.
Jorge Zorzopulos, Steven M Opal, Andrés Hernando-Insúa, Juan M Rodriguez, Fernanda Elías

World J Stem Cells· March 2017

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PyNTTTTGT and CpG immunostimulatory oligonucleotides: effect on granulocyte/monocyte colony-stimulating factor (GM-CSF) secretion by human CD56+ (NK and NKT) cells.
Juan M Rodriguez, José Marchicio, Mariela López, Andrea Ziblat, Fernanda Elias

PLoS One· December 2015

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Non-clinical safety studies of IMT504, a unique non-CpG oligonucleotide.
Raúl Franco, Juan M Rodriguez, Fernanda Elías, Andrés Hernando-Insúa, Juan Fló

Nucleic Acid Ther· August 2014

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Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire.
Alejandro Daniel Montaner, Analía Denichilo, Juan Manuel Rodríguez, Juan Fló, Ricardo Agustin López

Nucleic Acid Ther· August 2011

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A high dose of IMT504, the PyNTTTTGT prototype immunostimulatory oligonucleotide, does not alter embryonic development in rats.
Andrés Hernando-Insúa, Juan M Rodriguez, Fernanda Elías, Juan Fló, Ricardo López

Oligonucleotides· February 2010

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IMT504, the prototype of the immunostimulatory oligonucleotides of the PyNTTTTGT class, increases the number of progenitors of mesenchymal stem cells both in vitro and in vivo: potential use in tissue repair therapy.
Andrés Hernando Insúa, Alejandro D Montaner, Juan M Rodriguez, Fernanda Elías, Juan Fló

Stem Cells· April 2007

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Immunostimulatory PyNTTTTGT oligodeoxynucleotides: structural properties and refinement of the active motif.
Juan M Rodriguez, Fernanda Elías, Juan Fló, Ricardo A López, Jorge Zorzopulos

Oligonucleotides· December 2006

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Oligonucleotide IMT504 induces an immunogenic phenotype and apoptosis in chronic lymphocytic leukemia cells.
Juan M Rodriguez, Fernanda Elias, Alejandro Montaner, Juan Flo, Ricardo A Lopez

Medicina (B Aires)· August 2006

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Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route.
Alejandro D Montaner, Analía De Nichilo, Fernanda Elias, Juan M Rodríguez, Juan M Fló

Vaccine· March 2006

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Induction of p19INK4d in response to ultraviolet light improves DNA repair and confers resistance to apoptosis in neuroblastoma cells.
Julieta M Ceruti, María E Scassa, Juan M Fló, Cecilia L Varone, Eduardo T Cánepa

Oncogene· June 2005

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PyNTTTTGT prototype oligonucleotide IMT504 is a potent adjuvant for the recombinant hepatitis B vaccine that enhances the Th1 response.
Fernanda Elias, Juan Flo, Juan M Rodriguez, Analia De Nichilo, Ricardo A Lopez

Vaccine· May 2005

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Strong cytosine-guanosine-independent immunostimulation in humans and other primates by synthetic oligodeoxynucleotides with PyNTTTTGT motifs.
Fernanda Elias, Juan Flo, Ricardo A Lopez, Jorge Zorzopulos, Alejandro Montaner

J Immunol· October 2003

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Immunostimulatory effects of plasmid DNA and synthetic oligodeoxynucleotides.
Santiago Zelenay, Fernanda Elías, Juan Fló

Eur J Immunol· May 2003

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Co-immunization with plasmids coding the full length and a soluble form of glycoprotein D of HSV-2 induces protective cellular and humoral immune response in mice.
Juan Fló

Vaccine· March 2003

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Modulation of the immune response mediated by oral transgene administration of IL-10.
Fernanda Elías, Juan Fló

Cell Immunol· January 2003

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