Publications by authors named "Juan Rodrigues"

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Antimalarial Activity of Highly Coordinative Fused Heterocycles Targeting βHematin Crystallization.
María E Acosta, Lourdes Gotopo, Neira Gamboa, Juan R Rodrigues, Genesis C Henriques

ACS Omega· March 2022

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Synthesis and in silico ADME/Tox profiling studies of heterocyclic hybrids based on chloroquine scaffolds with potential antimalarial activity.
Hegira Ramírez, Esteban Fernandez-Moreira, Juan R Rodrigues, Michael R Mijares, Jorge E Ángel

Parasitol Res· January 2022

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Synthesis of 5H-indeno[1,2-b]pyridine derivatives: Antiproliferative and antimetastatic activities against two human prostate cancer cell lines.
Katiuska E Charris, Juan R Rodrigues, Hegira Ramírez, Esteban Fernandez-Moreira, Jorge E Ángel

Arch Pharm (Weinheim)· August 2021

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Synthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties.
Hegira Ramírez, Esteban Fernandez, Juan Rodrigues, Soriuska Mayora, Gricelis Martínez

Arch Pharm (Weinheim)· July 2021

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Synthesis, β-hematin inhibition studies and antimalarial evaluation of new dehydroxy isoquine derivatives against Plasmodium berghei: A promising antimalarial agent.
Edgar A Valverde, Angel H Romero, María E Acosta, Neira Gamboa, Genesis Henriques, Juan R Rodrigues

Eur J Med Chem· March 2018

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Antimalarial Activity of some Kaurenes.
Thayded Villasmil, Julio Rojas, Rosa Aparicioa, Neira Gamboa, Maria Eugenia Acosta, Juan Rodrigues

Nat Prod Commun· February 2017

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Synthesis, crystal structure and effect of indeno[1,2-b]indole derivatives on prostate cancer in vitro. Potential effect against MMP-9.
Gricela Lobo, Melina Monasterios, Juan Rodrigues, Neira Gamboa, Mario V Capparelli

Eur J Med Chem· April 2016

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Toxicological effects of thiomersal and ethylmercury: Inhibition of the thioredoxin system and NADP(+)-dependent dehydrogenases of the pentose phosphate pathway.
Juan Rodrigues, Vasco Branco, Jun Lu, Arne Holmgren, Cristina Carvalho

Toxicol Appl Pharmacol· August 2015

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Synthesis and antimalarial activity of urenyl Bis-chalcone in vitro and in vivo.
José N Domínguez, Neira Gamboa de Domínguez, Juan Rodrigues, María Eugenia Acosta, Noris Caraballo

J Enzyme Inhib Med Chem· December 2013

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Potential antitumour and pro-oxidative effects of (E)-methyl 2-(7-chloroquinolin-4-ylthio)-3-(4-hydroxyphenyl) acrylate (QNACR).
Juan R Rodrigues, Rosa Ferrer, Neira Gamboa, Jaime Charris, Fernando Antunes

J Enzyme Inhib Med Chem· December 2013

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N'-Formyl-2-(5-nitrothiophen-2-yl)benzothiazole-6-carbohydrazide as a potential anti-tumour agent for prostate cancer in experimental studies.
Juan R Rodrigues, Jaime Charris, José Camacho, Arthur Barazarte, Neira Gamboa

J Pharm Pharmacol· March 2013

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Effect of quinolinyl acrylate derivatives on prostate cancer in vitro and in vivo.
Juan R Rodrigues, Jaime Charris, Rosa Ferrer, Neira Gamboa, Jorge Angel

Invest New Drugs· August 2012

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Cytotoxic effects of N'-formyl-2-(5-nitrothiophen-2-yl) benzothiazole-6-carbohydrazide in human breast tumor cells by induction of oxidative stress.
Juan R Rodrigues, Jaime Charris, José Camacho, Arthur Barazarte, Neira Gamboa

Anticancer Res· July 2012

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Disturbance in hemoglobin metabolism and in vivo antimalarial activity of azole antimycotics.
Juan Ricardo Rodrigues, Diana Lourenco, Neira Gamboa

Rev Inst Med Trop Sao Paulo· August 2011

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New 4-maleamic acid and 4-maleamide peptidyl chalcones as potential multitarget drugs for human prostate cancer.
Juan Rodrigues, Claudia Abramjuk, Luis Vásquez, Neira Gamboa, José Domínguez

Pharm Res· April 2011

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Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents.
José Camacho, Arthur Barazarte, Neira Gamboa, Juan Rodrigues, Rosario Rojas

Bioorg Med Chem· March 2011

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Synthesis and antimalarial activities of optically active labdane-type diterpenes.
José Villamizar, Jean P Pittelaud, Juan R Rodrigues, Neira Gamboa, Nieves Canudas

Nat Prod Res· September 2009

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Modification of oxidative status in Plasmodium berghei-infected erythrocytes by E-2-chloro-8-methyl-3-[(4'-methoxy-1'-indanoyl)-2'-methyliden]-quinoline compared to chloroquine.
Juan Rodrigues, Jaime Charris, José Domínguez, Jorge Angel, Neira Gamboa

Mem Inst Oswaldo Cruz· September 2009

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Effect of dequalinium on the oxidative stress in Plasmodium berghei-infected erythrocytes.
Juan R Rodrigues, Neira D Gamboa

Parasitol Res· June 2009

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Synthesis of chlorovinyl sulfones as structural analogs of chalcones and their antiplasmodial activities.
Jose N Dominguez, Caritza Leon, Juan Rodrigues, Neira Gamboa de Dominguez, Jiri Gut

Eur J Med Chem· April 2009

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Synthesis and antimalarial activity of pyrazolo and pyrimido benzothiazine dioxide derivatives.
Arthur Barazarte, Gricela Lobo, Neira Gamboa, Juan R Rodrigues, Mario V Capparelli

Eur J Med Chem· March 2009

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Synthesis, antimalarial activity, structure-activity relationship analysis of thieno-[3,2-b]benzothiazine S,S-dioxide analogs.
Arthur Barazarte, José Camacho, José Domínguez, Gricela Lobo, Neira Gamboa, Juan Rodrigues

Bioorg Med Chem· April 2008

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Cytotoxic and apoptosis-inducing effect of ent-15-oxo-kaur-16-en-19-oic acid, a derivative of grandiflorolic acid from Espeletia schultzii.
Yarimar Ruiz, Juan Rodrígues, Francisco Arvelo, Alfredo Usubillaga, Mariugenia Monsalve

Phytochemistry· January 2008

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Urban malaria in the Brazilian Western Amazon Region I: high prevalence of asymptomatic carriers in an urban riverside district is associated with a high level of clinical malaria.
Mauro Shugiro Tada, Russimeire Paula Marques, Elieth Mesquita, Rosimeire Cristina Dalla Martha, Juan Abel Rodrigues

Mem Inst Oswaldo Cruz· June 2007

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Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties.
Muhammad Zareef, Rashid Iqbal, Neira Gamboa De Dominguez, Juan Rodrigues, Javid H Zaidi

J Enzyme Inhib Med Chem· June 2007

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