Publications by authors named "Judith Clements"

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Prostate cancer risk-associated single-nucleotide polymorphisms impact the conformational dynamics of prostate-specific antigen.
Srilakshmi Srinivasan, Brooke K Hayes, Mauricio G S Costa, Blake T Riley, Emily Wilson, Judith Clements

BMC Biol· December 2025

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Rewriting androgen-targeted therapy resistance with non-coding RNAs in prostate cancer treatment.
Chamikara Liyanage, Judith Clements, Jyotsna Batra

Mol Ther· November 2025

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Lactoferrin-encapsulated dichloroacetophenone (DAP) nanoparticles enhance drug delivery and anti-tumor efficacy in prostate cancer.
Sugarniya Subramaniam, Varinder Jeet, Jennifer H Gunter, Taskeen Janjua Khan, Yuran Feng, Judith A Clements

Cancer Lett· April 2025

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Iroquois homeobox 4 (IRX4) derived micropeptide promotes prostate cancer progression and chemoresistance through Wnt signalling dysregulation.
Achala Fernando, Chamikara Liyanage, Srilakshmi Srinivasan, Janaththani Panchadsaram, Joseph A Rothnagel, Judith Clements

Commun Med (Lond)· November 2024

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A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer.
Srilakshmi Srinivasan, Thomas Kryza, Nathalie Bock, Brian W C Tse, Kamil A Sokolowski, Judith Clements

Nat Commun· November 2024

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Glycolysis, the sweet appetite of the tumor microenvironment.
Zeinab Kooshan, Lilibeth Cárdenas-Piedra, Judith Clements, Jyotsna Batra

Cancer Lett· September 2024

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Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants.
Anqi Wang, Jiayi Shen, Alex A Rodriguez, Edward J Saunders, Fei Chen, Judith A Clements

Nat Genet· December 2023

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Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer.
Fatemeh Davoudi, Afshin Moradi, Therese M Becker, John G Lock, Brian Abbey, Judith Clements

Curr Treat Options Oncol· October 2023

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Unravelling the Role of Iroquois Homeobox 4 and its Interplay with Androgen Receptor in Prostate Cancer.
Panchadsaram Janaththani, Gregor Tevz, Achala Fernando, Adil Malik, Anja Rockstroh, Judith Clements

Res Sq· October 2023

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Characterisation of cell lines derived from prostate cancer patients with localised disease.
Leire Moya, Carina Walpole, Fiona Rae, Srilakshmi Srinivasan, Inge Seim, Judith A Clements

Prostate Cancer Prostatic Dis· September 2023

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Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
Burcu F Darst, Jiayi Shen, Ravi K Madduri, Alexis A Rodriguez, Yukai Xiao, Judith A Clements

Am J Hum Genet· July 2023

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The roles of proteases in prostate cancer.
Hannu Koistinen, Ruusu-Maaria Kovanen, Morley D Hollenberg, Antoine Dufour, Evette S Radisky, Judith Clements

IUBMB Life· June 2023

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GelMA and Biomimetic Culture Allow the Engineering of Mineralized, Adipose, and Tumor Tissue Human Microenvironments for the Study of Advanced Prostate Cancer In Vitro and In Vivo.
Agathe Bessot, Jennifer Gunter, David Waugh, Judith A Clements, Dietmar W Hutmacher

Adv Healthc Mater· June 2023

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Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry.
Burcu F Darst, Jiayi Shen, Ravi K Madduri, Alexis A Rodriguez, Yukai Xiao, Judith A Clements

medRxiv· May 2023

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Biochemical activity induced by a germline variation in (PSA) associates with cellular function and clinical outcome in prostate cancer.
Srilakshmi Srinivasan, Thomas Kryza, Nathalie Bock, Brian Wc Tse, Kamil A Sokolowski, Judith Clements

Res Sq· March 2023

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Remodelling of the tumour microenvironment by the kallikrein-related peptidases.
Srilakshmi Srinivasan, Thomas Kryza, Jyotsna Batra, Judith Clements

Nat Rev Cancer· April 2022

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A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.
Jacqui A McGovern, Nathalie Bock, Abbas Shafiee, Laure C Martine, Ferdinand Wagner, Judith A Clements

Commun Biol· August 2021

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Allele-Specific MicroRNA-Mediated Regulation of a Glycolysis Gatekeeper PDK1 in Cancer Metabolism.
Sugarniya Subramaniam, Varinder Jeet, Jennifer H Gunter, Judith A Clements, Jyotsna Batra

Cancers (Basel)· July 2021

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A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer.
Scott Lovell, Leran Zhang, Thomas Kryza, Anna Neodo, Nathalie Bock, Judith A Clements

J Am Chem Soc· June 2021

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In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer.
Nathalie Bock, Thomas Kryza, Ali Shokoohmand, Joan Röhl, Akhilandeshwari Ravichandran, Judith A Clements

Sci Adv· June 2021

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KLK3 SNP-SNP interactions for prediction of prostate cancer aggressiveness.
Hui-Yi Lin, Po-Yu Huang, Chia-Ho Cheng, Heng-Yuan Tung, Zhide Fang, Judith Clements

Sci Rep· April 2021

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Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
David V Conti, Burcu F Darst, Lilit C Moss, Edward J Saunders, Xin Sheng, Judith A Clements

Nat Genet· March 2021

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SWATH-MS Based Proteomic Profiling of Prostate Cancer Cells Reveals Adaptive Molecular Mechanisms in Response to Anti-Androgen Therapy.
Chamikara Liyanage, Adil Malik, Pevindu Abeysinghe, Judith Clements, Jyotsna Batra

Cancers (Basel)· February 2021

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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction.
David V Conti, Burcu F Darst, Lilit C Moss, Edward J Saunders, Xin Sheng, Judith A Clements

Nat Genet· January 2021

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KLK4 Induces Anti-Tumor Effects in Human Xenograft Mouse Models of Orthotopic and Metastatic Prostate Cancer.
Brian W-C Tse, Thomas Kryza, Mei-Chun Yeh, Ying Dong, Kamil A Sokolowski, Judith A Clements

Cancers (Basel)· November 2020

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