Publications by authors named "Judith Hyle"

Claim this Profile
D
Deciphering acquired resistance mechanisms to sustained auxin-inducible protein degradation in cells and mice.
Judith Hyle, Zhenling Liu, Shaela Fields, Jifeng Yang, Xinyan Chen

bioRxiv· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deciphering the role of RNA in regulating CTCF's DNA binding affinity in leukemia cells.
Judith Hyle, Wenjie Qi, Mohamed Nadhir Djekidel, Wojciech Rosikiewicz, Beisi Xu

Genome Biol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis.
Xue Yang, Li Cheng, Ye Xin, Jianxiang Zhang, Xinfeng Chen, Judith Hyle

Genome Biol· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9.
Mengli Zhang, Judith Hyle, Xiaowen Chen, Ye Xin, Yingcai Jin

Genome Biol· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Systematic characterization of the HOXA9 downstream targets in MLL-r leukemia by noncoding CRISPR screens.
Shaela Wright, Xujie Zhao, Wojciech Rosikiewicz, Shelby Mryncza, Judith Hyle

Nat Commun· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens.
Shaela Wright, Jianzhong Hu, Hong Wang, Judith Hyle, Yang Zhang

Proc Natl Acad Sci U S A· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation.
Judith Hyle, Mohamed Nadhir Djekidel, Justin Williams, Shaela Wright, Ying Shao

Genome Biol· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Acute depletion of CTCF rewires genome-wide chromatin accessibility.
Beisi Xu, Hong Wang, Shaela Wright, Judith Hyle, Yang Zhang

Genome Biol· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen.
Hao Zhang, Yang Zhang, Xinyue Zhou, Shaela Wright, Judith Hyle

Elife· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X.
Yu Liu, Chunliang Li, Shuhong Shen, Xiaolong Chen, Karol Szlachta, Judith Hyle

Nat Genet· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A -element within the locus mediates repression of expression via long-range chromatin interactions.
Yang Zhang, Judith Hyle, Shaela Wright, Ying Shao, Xujie Zhao

Proc Natl Acad Sci U S A· December 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Acute depletion of CTCF directly affects MYC regulation through loss of enhancer-promoter looping.
Judith Hyle, Yang Zhang, Shaela Wright, Beisi Xu, Ying Shao

Nucleic Acids Res· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.
BaoHan T Vo, Chunliang Li, Marc A Morgan, Ilan Theurillat, David Finkelstein, Judith Hyle

Cell Rep· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Simultaneous gene editing by injection of mRNAs encoding transcription activator-like effector nucleases into mouse zygotes.
Chunliang Li, Rong Qi, Rebecca Singleterry, Judith Hyle, Amanda Balch

Mol Cell Biol· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mammalian ChlR1 has a role in heterochromatin organization.
Akira Inoue, Judith Hyle, Mark S Lechner, Jill M Lahti

Exp Cell Res· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing.
Pascal Loyer, Adeline Busson, Janeen H Trembley, Judith Hyle, Jose Grenet

J Biol Chem· January 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.
Chandraiah Lagisetti, Alan Pourpak, Tinopiwa Goronga, Qin Jiang, Xiaoli Cui, Judith Hyle

J Med Chem· November 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion.
Akira Inoue, Judith Hyle, Mark S Lechner, Jill M Lahti

Mutat Res· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Detection of the mycophenolate-inhibited form of IMP dehydrogenase in vivo.
Christine C McPhillips, Judith W Hyle, Daniel Reines

Proc Natl Acad Sci U S A· August 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast.
Judith W Hyle, Randal J Shaw, Daniel Reines

J Biol Chem· August 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis