Publications by authors named "Judith Murray-Rust"

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Oncogenic RET kinase domain mutations perturb the autophosphorylation trajectory by enhancing substrate presentation in trans.
Iván Plaza-Menacho, Karin Barnouin, Kerry Goodman, Rubén J Martínez-Torres, Annabel Borg, Judith Murray-Rust

Mol Cell· March 2014

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Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes.
Svend Kjær, Mark Linch, Andrew Purkiss, Brenda Kostelecky, Phillip P Knowles, Judith Murray-Rust

Biochem J· April 2013

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Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
Batiste Boëda, Phillip P Knowles, David C Briggs, Judith Murray-Rust, Erika Soriano

J Biol Chem· April 2011

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Endothelial, sympathetic, and cardiac function in inherited (6R)-L-erythro-5,6,7,8-tetrahydro-L-biopterin deficiency.
Lila Mayahi, Lydia Mason, Katherine Bleasdale-Barr, Ann Donald, Iris Trender-Gerhard, Judith Murray-Rust

Circ Cardiovasc Genet· December 2010

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Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors.
Luca Mologni, Roberta Rostagno, Stefania Brussolo, Phillip P Knowles, Svend Kjaer, Judith Murray-Rust

Bioorg Med Chem· February 2010

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Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.
Sadaf Shadan, Roman Holic, Nicolas Carvou, Patrick Ee, Michelle Li, Judith Murray-Rust

Traffic· September 2008

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Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor.
Rebecca Kirk, Heike Laman, Phillip P Knowles, Judith Murray-Rust, Mikhail Lomonosov

J Biol Chem· August 2008

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Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.
Basil Hartzoulakis, Sharon Rossiter, Herpreet Gill, Bernard O'Hara, Emily Steinke

Bioorg Med Chem Lett· July 2007

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Disruption of methylarginine metabolism impairs vascular homeostasis.
James Leiper, Manasi Nandi, Belen Torondel, Judith Murray-Rust, Mohammed Malaki

Nat Med· February 2007

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Structure and chemical inhibition of the RET tyrosine kinase domain.
Phillip P Knowles, Judith Murray-Rust, Svend Kjaer, Rizaldy P Scott, Sarah Hanrahan

J Biol Chem· November 2006

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Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition.
Matthew Newman, Judith Murray-Rust, John Lally, Jana Rudolf, Andrew Fadden

EMBO J· March 2005

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Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
Clive P Morgan, Alison Skippen, Bruno Segui, Andrew Ball, Victoria Allen-Baume, Judith Murray-Rust

J Biol Chem· November 2004

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Crystallization of the xeroderma pigmentosum group F endonuclease from Aeropyrum pernix.
John Lally, Matthew Newman, Judith Murray-Rust, Andrew Fadden, Yutaka Kawarabayasi

Acta Crystallogr D Biol Crystallogr· September 2004

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The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.
Farahnaz Movahedzadeh, Debbie A Smith, Richard A Norman, Premkumar Dinadayala, Judith Murray-Rust

Mol Microbiol· February 2004

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Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.
Sarah J Tilley, Alison Skippen, Judith Murray-Rust, Philip M Swigart, Albert Stewart

Structure· February 2004

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PKC at a glance.
Peter J Parker, Judith Murray-Rust

J Cell Sci· January 2004

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S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase.
James Leiper, Judith Murray-Rust, Neil McDonald, Patrick Vallance

Proc Natl Acad Sci U S A· October 2002

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Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis.
Richard A Norman, Mark S B McAlister, Judith Murray-Rust, Farahnaz Movahedzadeh, Neil G Stoker

Structure· March 2002

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