Publications by authors named "Judith Steen"

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Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration.
Melissa E Murray, Colin Smith, Vilas Menon, C Dirk Keene, Ed Lein, Judith A Steen

Neuron· November 2025

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Mass-spectrometry-based proteomics: from single cells to clinical applications.
Tiannan Guo, Judith A Steen, Matthias Mann

Nature· February 2025

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Dementia with lewy bodies patients with high tau levels display unique proteome profiles.
Sinead Greally, Mukesh Kumar, Christoph Schlaffner, Hanne van der Heijden, Elisabeth S Lawton, Hanno Steen, Judith A Steen

Mol Neurodegener· December 2024

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Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes.
Arthur Viode, Kinga K Smolen, Patrick van Zalm, David Stevenson, Meenakshi Jha, Judith A Steen, Hanno Steen

Sci Adv· May 2024

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Quantitative profiling of posttranslational modifications of pathological tau via sarkosyl fractionation and mass spectrometry.
Kathrin Wenger, Arthur Viode, Mukesh Kumar, Hanno Steen, Judith A Steen

Nat Protoc· April 2024

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Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments.
Mukesh Kumar, Noé Quittot, Simon Dujardin, Christoph N Schlaffner, Arthur Viode, Judith A Steen

Brain· February 2024

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Integrative systems biology characterizes immune-mediated neurodevelopmental changes in murine Zika virus microcephaly.
Kimino Fujimura, Amanda J Guise, Tojo Nakayama, Christoph N Schlaffner, Anais Meziani, Hanno Steen, Judith A Steen

iScience· July 2023

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Meta-analysis of published cerebrospinal fluid proteomics data identifies and validates metabolic enzyme panel as Alzheimer's disease biomarkers.
Patrick W van Zalm, Saima Ahmed, Benoit Fatou, Rudy Schreiber, Omar Barnaby, Judith A Steen, Hanno Steen

Cell Rep Med· April 2023

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A simple, time- and cost-effective, high-throughput depletion strategy for deep plasma proteomics.
Arthur Viode, Patrick van Zalm, Kinga K Smolen, Benoit Fatou, David Stevenson, Judith Steen, Hanno Steen

Sci Adv· March 2023

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Common mouse models of tauopathy reflect early but not late human disease.
Kathrin Wenger, Arthur Viode, Christoph N Schlaffner, Patrick van Zalm, Long Cheng, Hanno Steen, Judith A Steen

Mol Neurodegener· February 2023

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Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System.
Saima Ahmed, Patrick van Zalm, Emily A Rudmann, Michael Leone, Kiana Keller, Judith Steen, Hanno Steen

Viruses· December 2022

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A Parallelization Strategy for the Time Efficient Analysis of Thousands of LC/MS Runs in High-Performance Computing Environment.
Patrick van Zalm, Arthur Viodé, Kinga Smolen, Benoit Fatou, Arash Nemati Hayati, Judith Steen, Hanno Steen

J Proteome Res· November 2022

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Using plasma proteomics to investigate viral infections of the central nervous system including patients with HIV-associated neurocognitive disorders.
Saima Ahmed, Arthur Viode, Patrick van Zalm, Judith Steen, Shibani S Mukerji, Hanno Steen

J Neurovirol· June 2022

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Urine Proteomics for Noninvasive Monitoring of Biomarkers in Bronchopulmonary Dysplasia.
Saima Ahmed, Oludare A Odumade, Patrick van Zalm, Kinga K Smolen, Kimino Fujimura, Judith A Steen, Hanno Steen

Neonatology· April 2022

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multiFLEX-LF: A Computational Approach to Quantify the Modification Stoichiometries in Label-Free Proteomics Data Sets.
Pauline Hiort, Christoph N Schlaffner, Judith A Steen, Bernhard Y Renard, Hanno Steen

J Proteome Res· April 2022

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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains.
Tamta Arakhamia, Christina E Lee, Yari Carlomagno, Mukesh Kumar, Duc M Duong, Judith A Steen

Cell· December 2021

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FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply.
Himanish Basu, Gulcin Pekkurnaz, Jill Falk, Wei Wei, Morven Chin, Judith Steen

J Cell Biol· October 2021

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Phosphorylation-dependent control of Activity-regulated cytoskeleton-associated protein (Arc) protein by TNIK.
Alicyia Walczyk-Mooradally, Jennifer Holborn, Karamjeet Singh, Marshall Tyler, Debasis Patnaik, Judith Steen

J Neurochem· September 2021

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Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Simon Dujardin, Caitlin Commins, Aurelien Lathuiliere, Pieter Beerepoot, Analiese R Fernandes, Judith A Steen

Nat Med· February 2021

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Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.
Hendrik Wesseling, Waltraud Mair, Mukesh Kumar, Christoph N Schlaffner, Shaojun Tang, Hanno Steen, Judith A Steen

Cell· December 2020

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FLEXIQuant-LF to quantify protein modification extent in label-free proteomics data.
Christoph N Schlaffner, Konstantin Kahnert, Jan Muntel, Ruchi Chauhan, Bernhard Y Renard, Judith A Steen, Hanno Steen

Elife· December 2020

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Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Simon Dujardin, Caitlin Commins, Aurelien Lathuiliere, Pieter Beerepoot, Analiese R Fernandes, Judith A Steen

Nat Med· August 2020

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Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain.
Darshan Sapkota, Allison M Lake, Wei Yang, Chengran Yang, Hendrik Wesseling, Judith A Steen

Cell Rep· January 2019

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A Cost-Effective High-Throughput Plasma and Serum Proteomics Workflow Enables Mapping of the Molecular Impact of Total Pancreatectomy with Islet Autotransplantation.
Tue Bjerg Bennike, Melena D Bellin, Yue Xuan, Allan Stensballe, Frederik Trier Møller, Judith Steen, Hanno Steen

J Proteome Res· May 2018

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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes.
Christoph N Schlaffner, Georg J Pirklbauer, Andreas Bender, Judith A J Steen, Jyoti S Choudhary

J Vis Exp· May 2018

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