Publications by authors named "Julia A Tree"

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Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Julia A Tree, Jeremy E Turnbull, Karen R Buttigieg, Michael J Elmore, Naomi Coombes, John Hogwood, Courtney J Mycroft-West, Marcelo A Lima, Mark A Skidmore, Richard Karlsson

Br J Pharmacol· February 2021

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Publisher Correction: Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab') fragments.
Stephen Findlay-Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Matthew Aldridge, Julia A Tree

Sci Rep· September 2023

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Refinement of an ovine-based immunoglobulin therapy against SARS-CoV-2, with comparison of whole IgG versus F(ab') fragments.
Stephen Findlay-Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Matthew Aldridge, Julia A Tree

Sci Rep· August 2023

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Inhibition of phosphodiesterase 12 results in antiviral activity against several RNA viruses including SARS-CoV-2.
Mark Thursz, Fouzia Sadiq, Julia A Tree, Peter Karayiannis, David W C Beasley

J Gen Virol· July 2023

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Corrigendum: Inhibition of phosphodiesterase 12 results in antiviral activity against several RNA viruses including SARS-CoV-2.
Mark Thursz, Fouzia Sadiq, Julia A Tree, Peter Karayiannis, David W C Beasley

J Gen Virol· July 2023

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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T Shawli, Julia A Tree

Genome Biol· March 2023

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Development of a cost-effective ovine antibody-based therapy against SARS-CoV-2 infection and contribution of antibodies specific to the spike subunit proteins.
Stephen Findlay-Wilson, Linda Easterbrook, Sandra Smith, Neville Pope, Gareth Humphries, Julia Anne Tree

Antiviral Res· July 2022

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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction.
Scott E Guimond, Courtney J Mycroft-West, Neha S Gandhi, Julia A Tree, Thuy T Le

ACS Cent Sci· May 2022

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Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2.
Kuan-Ying A Huang, Daming Zhou, Tiong Kit Tan, Charles Chen, Helen M E Duyvesteyn, Julia A Tree

Theranostics· January 2022

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A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Jiandong Huo, Halina Mikolajek, Audrey Le Bas, Jordan J Clark, Parul Sharma, Julia A Tree

Nat Commun· September 2021

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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Jiandong Huo, Audrey Le Bas, Reinis R Ruza, Helen M E Duyvesteyn, Halina Mikolajek, Julia A Tree

Nat Struct Mol Biol· March 2021

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Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19.
Francisco J Salguero, Andrew D White, Gillian S Slack, Susan A Fotheringham, Kevin R Bewley, Julia A Tree

Nat Commun· February 2021

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Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity.
Kathryn A Ryan, Kevin R Bewley, Susan A Fotheringham, Gillian S Slack, Phillip Brown, Julia A Tree

Nat Commun· January 2021

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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses.
Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, Anthony H Keeble, Lisa Schimanski, Julia A Tree

Nat Commun· January 2021

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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Jiangdong Huo, Audrey Le Bas, Reinis R Ruza, Helen M E Duyvesteyn, Halina Mikolajek, Julia A Tree

Nat Struct Mol Biol· November 2020

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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Daming Zhou, Helen M E Duyvesteyn, Cheng-Pin Chen, Chung-Guei Huang, Ting-Hua Chen, Julia A Tree

Nat Struct Mol Biol· October 2020

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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.
Jiandong Huo, Yuguang Zhao, Jingshan Ren, Daming Zhou, Helen M E Duyvesteyn, Julia A Tree

Cell Host Microbe· September 2020

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Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Jiandong Huo, Audrey Le Bas, Reinis R Ruza, Helen M E Duyvesteyn, Halina Mikolajek, Julia A Tree

Nat Struct Mol Biol· September 2020

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Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.
Jiandong Huo, Yuguang Zhao, Jingshan Ren, Daming Zhou, Helen M E Duyvesteyn, Julia A Tree

Cell Host Microbe· September 2020

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A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction.
Monir Ejemel, Qi Li, Shurong Hou, Zachary A Schiller, Julia A Tree

Nat Commun· August 2020

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Repeated high-dose (5 × 10(8) TCID50) toxicity study of a third generation smallpox vaccine (IMVAMUNE) in New Zealand white rabbits.
Julia A Tree, Graham Hall, Peter Rees, Julia Vipond, Simon G P Funnell

Hum Vaccin Immunother· July 2016

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Vaccines and therapies for biodefence agents.
Julia A Tree, E Diane Williamson, Caroline A Rowland, Louise M Pitt

J Immunol Res· January 2016

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The impact of "omic" and imaging technologies on assessing the host immune response to biodefence agents.
Julia A Tree, Helen Flick-Smith, Michael J Elmore, Caroline A Rowland

J Immunol Res· June 2015

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Evidence for a role for interleukin-17, Th17 cells and iron homeostasis in protective immunity against tuberculosis in cynomolgus macaques.
Alice S Wareham, Julia A Tree, Philip D Marsh, Philip D Butcher, Mike Dennis

PLoS One· September 2014

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Assessment of the protective effect of Imvamune and Acam2000 vaccines against aerosolized monkeypox virus in cynomolgus macaques.
Graham J Hatch, Victoria A Graham, Kevin R Bewley, Julia A Tree, Mike Dennis

J Virol· July 2013

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