Publications by authors named "Julie D Forman-Kay"

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Zero-shot segmentation using embeddings from a protein language model identifies functional regions in the human proteome.
Ami G Sangster, Cameron Dufault, Haoning Qu, Denise Le, Julie D Forman-Kay

PLoS Comput Biol· November 2025

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The dynamic and heterogeneous composition of biomolecular condensates and its functional relevance.
Christopher Chin Sang, Sayantani Upadhyay, Michael L Nosella, Julie D Forman-Kay, Hyun O Lee

Nat Rev Mol Cell Biol· November 2025

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Mutations in the β-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes.
Antonio Mollica, Safia Omer, Georgiana Forguson, Sydney Steiman, Sonia L Evagelou, Julie D Forman-Kay

Nat Commun· November 2025

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AlphaFlex: Ensembles of the human proteome representing disordered regions.
Zi Hao Liu, Oufan Zhang, Stefano De Castro, Kunyang Sun, Hamidreza Ghafouri, Julie D Forman-Kay

bioRxiv· November 2025

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Beyond peptide targeting sequences: machine learning of cellular condensate localization.
Jonathon A Ditlev, Julie D Forman-Kay

Cell Res· October 2025

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Atomic Resolution Interactions Regulating Partitioning of a FUS Folded RRM Domain into Model CAPRIN1 Condensates.
Rashik Ahmed, Jeffrey P Bonin, Julie D Forman-Kay, Lewis E Kay

J Am Chem Soc· September 2025

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Biological insights from integrative modeling of intrinsically disordered protein systems.
Zi Hao Liu, Maria Tsanai, Oufan Zhang, Teresa Head-Gordon, Julie D Forman-Kay

Curr Opin Struct Biol· August 2025

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Client-scaffold interactions suppress aggregation of a client protein in model condensates.
Rashik Ahmed, Rhea P Hudson, Julie D Forman-Kay, Lewis E Kay

Proc Natl Acad Sci U S A· August 2025

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Disorder meets its match.
Alan M Moses, Julie D Forman-Kay

Science· July 2025

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Essential lipids enrich membrane-associated condensates to rescue synaptic morpho-functional deficits in a mouse model of autism.
Jason Arsenault, Tian Kong, Rayan Saghian, Octavia Yifang Weng, Salil Saurav Pathak, Julie D Forman-Kay

Cell Rep· May 2025

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Electrostatics of salt-dependent reentrant phase behaviors highlights diverse roles of ATP in biomolecular condensates.
Yi-Hsuan Lin, Tae Hun Kim, Suman Das, Tanmoy Pal, Jonas Wessén, Julie D Forman-Kay

Elife· March 2025

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Deep Learning of Proteins with Local and Global Regions of Disorder.
Oufan Zhang, Zi Hao Liu, Julie D Forman-Kay, Teresa Head-Gordon

ArXiv· March 2025

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Protein interactions, calcium, phosphorylation, and cholesterol modulate CFTR cluster formation on membranes.
Yimei Wan, Rhea Hudson, Jordyn Smith, Julie D Forman-Kay, Jonathon A Ditlev

Proc Natl Acad Sci U S A· March 2025

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PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation.
Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Hongshan Zhang, Michael L Nosella, Julie D Forman-Kay

EMBO Rep· December 2024

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Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates.
Rashik Ahmed, Mingyang Liang, Rhea P Hudson, Atul K Rangadurai, Shuya Kate Huang, Julie D Forman-Kay

Proc Natl Acad Sci U S A· August 2024

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The TSC22D, WNK, and NRBP gene families exhibit functional buffering and evolved with Metazoa for cell volume regulation.
Yu-Xi Xiao, Seon Yong Lee, Magali Aguilera-Uribe, Reuben Samson, Aaron Au, Julie D Forman-Kay

Cell Rep· July 2024

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Chromosome compaction is triggered by an autonomous DNA-binding module within condensin.
Alyssa Pastic, Michael L Nosella, Annahat Kochhar, Zi Hao Liu, Julie D Forman-Kay

Cell Rep· July 2024

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Phase Separation Modulates the Thermodynamics and Kinetics of RNA Hybridization.
Atul K Rangadurai, Lisa Ruetz, Rashik Ahmed, Kristen Lo, Martin Tollinger, Julie D Forman-Kay

J Am Chem Soc· July 2024

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Intrinsic disorder: A term to define the specific physicochemical characteristic of protein conformational heterogeneity.
Edward A Lemke, M Madan Babu, Richard W Kriwacki, Tanja Mittag, Rohit V Pappu, Julie D Forman-Kay

Mol Cell· April 2024

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Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates.
Michael L Nosella, Tae Hun Kim, Shuya Kate Huang, Robert W Harkness, Monica Goncalves, Julie D Forman-Kay

Mol Cell· February 2024

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PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation.
Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Michael L Nosella, Hongshan Zhang, Julie D Forman-Kay

bioRxiv· January 2024

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Local Disordered Region Sampling (LDRS) for ensemble modeling of proteins with experimentally undetermined or low confidence prediction segments.
Zi Hao Liu, João M C Teixeira, Oufan Zhang, Thomas E Tsangaris, Jie Li, Julie D Forman-Kay

Bioinformatics· December 2023

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A FRET-Based Assay and Computational Tools to Quantify Enzymatic Rates and Explore the Mechanisms of RNA Deadenylases in Heterogeneous Environments.
Rose Irwin, Robert W Harkness, Julie D Forman-Kay

Methods Mol Biol· November 2023

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The Energetic Origins of Pi-Pi Contacts in Proteins.
Kevin Carter-Fenk, Meili Liu, Leila Pujal, Matthias Loipersberger, Maria Tsanai, Julie D Forman-Kay

J Am Chem Soc· November 2023

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Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2.
T Reid Alderson, Iva Pritišanac, Đesika Kolarić, Alan M Moses, Julie D Forman-Kay

Proc Natl Acad Sci U S A· October 2023

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