Publications by authors named "Jun Nakae"

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Macrophages play a crucial role in vascular smooth muscle cell coverage.
Kenta Niimi, Jun Nakae, Yoshiaki Kubota, Shinobu Inagaki, Tatsuo Furuyama

Development· September 2024

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FOXO1 represses lymphatic valve formation and maintenance via PRDM1.
Kenta Niimi, Jun Nakae, Shinobu Inagaki, Tatsuo Furuyama

Cell Rep· November 2021

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Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes.
Ryogo Furuhata, Yasuaki Kabe, Ayaka Kanai, Yuki Sugiura, Hitoshi Tsugawa, Jun Nakae

Commun Biol· September 2020

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The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B axis.
Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Jun Nakae

Proc Natl Acad Sci U S A· May 2020

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Tissue-Specific Metabolic Regulation of FOXO-Binding Protein: FOXO Does Not Act Alone.
Noriko Kodani, Jun Nakae

Cells· March 2020

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FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression.
Noriko Kodani, Jun Nakae, Masaki Kobayashi, Osamu Kikuchi, Tadahiro Kitamura

iScience· January 2020

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Foxo in T Cells Regulates Thermogenic Program through Ccr4/Ccl22 Axis.
Tetsuhiro Kikuchi, Jun Nakae, Yoshinaga Kawano, Nobuyuki Watanabe, Masafumi Onodera

iScience· December 2019

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Islet β-cell-produced NUCB2/nesfatin-1 maintains insulin secretion and glycemia along with suppressing UCP-2 in β-cells.
Yifei Yang, Boyang Zhang, Masanori Nakata, Jun Nakae, Masatomo Mori

J Physiol Sci· September 2019

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Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1.
Motoko Kita, Jun Nakae, Yoshinaga Kawano, Hiroshi Asahara, Hiroshi Takemori

iScience· February 2019

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Central insulin action induces activation of paraventricular oxytocin neurons to release oxytocin into circulation.
Boyang Zhang, Masanori Nakata, Jun Nakae, Wataru Ogawa, Toshihiko Yada

Sci Rep· July 2018

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Protective role of AgRP neuron's PDK1 against salt-induced hypertension.
Boyang Zhang, Masanori Nakata, Ming Lu, Jun Nakae, Takashi Okada

Biochem Biophys Res Commun· June 2018

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PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis.
Hideyuki Sasanuma, Masanori Nakata, Kumari Parmila, Jun Nakae, Toshihiko Yada

Mol Metab· May 2017

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Colonic Pro-inflammatory Macrophages Cause Insulin Resistance in an Intestinal Ccl2/Ccr2-Dependent Manner.
Yoshinaga Kawano, Jun Nakae, Nobuyuki Watanabe, Tetsuhiro Kikuchi, Sanshiro Tateya

Cell Metab· August 2016

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Involvement of SIK3 in glucose and lipid homeostasis in mice.
Tatsuya Uebi, Yumi Itoh, Osamu Hatano, Ayako Kumagai, Masato Sanosaka, Jun Nakae

PLoS One· December 2012

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Loss of Pdk1-Foxo1 signaling in myeloid cells predisposes to adipose tissue inflammation and insulin resistance.
Yoshinaga Kawano, Jun Nakae, Nobuyuki Watanabe, Shiho Fujisaka, Kristy Iskandar

Diabetes· August 2012

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Novel repressor regulates insulin sensitivity through interaction with Foxo1.
Jun Nakae, Yongheng Cao, Fumihiko Hakuno, Hiroshi Takemori, Yoshinaga Kawano

EMBO J· May 2012

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[Factors involved in insulin signaling].
Jun Nakae, Hiroshi Itoh

Nihon Rinsho· May 2012

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Constitutive expression of insulin receptor substrate (IRS)-1 inhibits myogenic differentiation through nuclear exclusion of Foxo1 in L6 myoblasts.
Fumihiko Hakuno, Yoko Yamauchi, Gen Kaneko, Yosuke Yoneyama, Jun Nakae

PLoS One· February 2012

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Overexpression of FoxO1 in the hypothalamus and pancreas causes obesity and glucose intolerance.
Hye-Jin Kim, Masaki Kobayashi, Tsutomu Sasaki, Osamu Kikuchi, Kosuke Amano, Jun Nakae

Endocrinology· February 2012

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PDK1-Foxo1 in agouti-related peptide neurons regulates energy homeostasis by modulating food intake and energy expenditure.
Yongheng Cao, Masanori Nakata, Shiki Okamoto, Eisuke Takano, Toshihiko Yada, Jun Nakae

PLoS One· October 2011

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Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle.
Noriaki Shimizu, Noritada Yoshikawa, Naoki Ito, Takako Maruyama, Yuko Suzuki, Jun Nakae

Cell Metab· February 2011

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Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes.
Nirmala Hariharan, Yasuhiro Maejima, Jun Nakae, Jihye Paik, Ronald A Depinho

Circ Res· December 2010

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PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake.
Kristy Iskandar, Yongheng Cao, Yoshitake Hayashi, Masanori Nakata, Eisuke Takano, Jun Nakae

Am J Physiol Endocrinol Metab· April 2010

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Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.
Yasuhide Fukatsu, Tetsuya Noguchi, Tetsuya Hosooka, Takeshi Ogura, Ko Kotani, Jun Nakae

Endocrinology· June 2009

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Inactivation of HDAC5 by SIK1 in AICAR-treated C2C12 myoblasts.
Hiroshi Takemori, Yoshiko Katoh Hashimoto, Jun Nakae, Eric N Olson, Mitsuhiro Okamoto

Endocr J· April 2009

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