Publications by authors named "Jun Sub Choi"

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Retinal Organoid-Derived Exosomes Reduce CNV Lesion and Restore RPE Integrity in Mouse Laser-Induced Choroidal Neovascularization (CNV) Model.
Jin Young Yang, Yeji Kim, Sumin An, Jung Woo Han, Jun-Sub Choi

Int J Mol Sci· November 2025

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Subretinal delivery of AAV5-mediated human gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa.
Hee Jong Kim, Ji Hoon Kwak, Jun Sub Choi, Jin Kim, Seo Yun Moon

Mol Vis· May 2025

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mTOR downregulation promotes anti-inflammatory responses via the CCL3-CCR5 axis in hypoxic retinopathy.
Tae Kwon Moon, Im Kyeung Kang, Kyoung Jin Lee, Ji Hyun Kim, Hee Jong Kim, Jun-Sub Choi

Mol Ther Methods Clin Dev· March 2025

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Therapeutic potential of AAV2-shmTOR gene therapy in reducing retinal inflammation and preserving endothelial Integrity in age-related macular degeneration.
Jin Kim, Seo Yun Moon, Ho Geun Kang, Hee Jong Kim, Jun Sub Choi

Sci Rep· March 2025

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An examination of the mechanisms driving the therapeutic effects of an AAV expressing a soluble variant of VEGF receptor-1.
Seo Yun Moon, Hee Jong Kim, Jin Kwon Kim, Jin Kim, Jun-Sub Choi

PLoS One· July 2024

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scAAV2-Mediated Expression of Thioredoxin 2 and C3 Transferase Prevents Retinal Ganglion Cell Death and Lowers Intraocular Pressure in a Mouse Model of Glaucoma.
Hee Jong Kim, Seho Cha, Jun-Sub Choi, Joo Yong Lee, Ko Eun Kim

Int J Mol Sci· November 2023

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mTOR inhibition as a novel gene therapeutic strategy for diabetic retinopathy.
Steven Hyun Seung Lee, Joo Yong Lee, Jun-Sub Choi, Hee Jong Kim, Jin Kim

PLoS One· June 2022

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AAV expressing an mTOR-inhibiting siRNA exhibits therapeutic potential in retinal vascular disorders by preserving endothelial integrity.
Seho Cha, Won-Il Seo, Ha-Na Woo, Hee Jong Kim, Steven Hyun Seung Lee, Jun-Sub Choi

FEBS Open Bio· January 2022

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In Vivo Efficacy of Imatinib Mesylate, a Tyrosine Kinase Inhibitor, in the Treatment of Chemically Induced Dry Eye in Animal Models.
Yi-Yong Baek, Bokyung Sung, Jun-Sub Choi, Hyeon-Kyu Go, Do-Hyung Kim

Transl Vis Sci Technol· September 2021

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Inhibition of mTOR via an AAV-Delivered shRNA Tested in a Rat OIR Model as a Potential Antiangiogenic Gene Therapy.
Steven Hyun Seung Lee, HeeSoon Chang, Ji Hyun Kim, Hee Jong Kim, Jun-Sub Choi

Invest Ophthalmol Vis Sci· February 2020

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Effects of Stuffer DNA on the Suppression of Choroidal Neovascularization by a rAAV Expressing a mTOR-Inhibiting shRNA.
Steven Hyun Seung Lee, HeeSoon Chang, Hee Jong Kim, Jun-Sub Choi, Jin Kim

Mol Ther Methods Clin Dev· September 2019

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Protective effect of RIPK1-inhibitory compound in in vivo models for retinal degenerative disease.
Ki-Hong Jang, Yun-Ju Do, Tae-Sung Koo, Jun-Sub Choi, Eun Ju Song

Exp Eye Res· March 2019

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Intravitreal Injection of AAV Expressing Soluble VEGF Receptor-1 Variant Induces Anti-VEGF Activity and Suppresses Choroidal Neovascularization.
Steven Hyun Seung Lee, Hee Jong Kim, Oh Kyu Shin, Jun-Sub Choi, Jin Kim

Invest Ophthalmol Vis Sci· November 2018

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Expression of MyoD, insulin like growth factor binding protein, thioredoxin and p27 in secondarily overacting inferior oblique muscles with superior oblique palsy.
Yeon Woong Chung, Jun Sub Choi, Sun Young Shin

BMC Ophthalmol· May 2018

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Ideal parameters for femto-second laser-assisted anterior capsulotomy: Animal studies.
Min-Ji Kang, Yong-Eun Lee, Jun-Sub Choi, Choun-Ki Joo

PLoS One· February 2018

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MiR-199a/b-5p Inhibits Lymphangiogenesis by Targeting Discoidin Domain Receptor 1 in Corneal Injury.
Sooeun Oh, Minkoo Seo, Jun-Sub Choi, Choun-Ki Joo, Suk Kyeong Lee

Mol Cells· February 2018

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Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization.
Tae Kwann Park, Si Hyung Lee, Jun Sub Choi, Seung Kwan Nah, Hee Jong Kim

Mol Ther Nucleic Acids· September 2017

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A Novel Peptide Derived From Tissue-Type Plasminogen Activator Potently Inhibits Angiogenesis and Corneal Neovascularization.
Hyun-Kyung Kim, Jun-Sub Choi, Seung Woo Lee, Choun-Ki Joo, Young Ae Joe

J Cell Biochem· May 2017

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AIF-independent parthanatos in the pathogenesis of dry age-related macular degeneration.
Ki-Hong Jang, Yun-Ju Do, Dongwon Son, Eunji Son, Jun-Sub Choi

Cell Death Dis· January 2017

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Reducible Polyethylenimine Nanoparticles for Efficient siRNA Delivery in Corneal Neovascularization Therapy.
Hyounkoo Han, Sohee Son, Sejin Son, Namho Kim, Ji Young Yhee, Jun-Sub Choi

Macromol Biosci· November 2016

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Two-photon microscopy of a Flt1 peptide-hyaluronate conjugate.
Songeun Beack, Jun-Sub Choi, Jun Ho Lee, Hyemin Kim, Ki Hean Kim

Nanomedicine (Lond)· June 2016

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Diquafosol promotes corneal epithelial healing via intracellular calcium-mediated ERK activation.
Yong-Soo Byun, Young-Sik Yoo, Ji-Young Kwon, Jong-Soo Joo, Sung-A Lim, Jun-Sub Choi

Exp Eye Res· February 2016

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Inhibition of Lymphangiogenesis and Hemangiogenesis in Corneal Inflammation by Subconjunctival Prox1 siRNA Injection in Rats.
Chang Rae Rho, Jun-Sub Choi, Minkoo Seo, Suk Kyeong Lee, Choun-Ki Joo

Invest Ophthalmol Vis Sci· September 2015

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Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization.
Byung-Hak Kim, Junyeop Lee, Jun-Sub Choi, Dae Young Park, Ho Young Song

Br J Pharmacol· August 2015

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MicroRNA miR-466 inhibits Lymphangiogenesis by targeting prospero-related homeobox 1 in the alkali burn corneal injury model.
Minkoo Seo, Jun-Sub Choi, Chang Rae Rho, Choun-Ki Joo, Suk Kyeong Lee

J Biomed Sci· January 2015

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