Publications by authors named "Jun-Sub Im"

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An aberrant immune-epithelial progenitor niche drives viral lung sequelae.
Harish Narasimhan, In Su Cheon, Wei Qian, Sheng'en Shawn Hu, Tanyalak Parimon, Jun Sub Im, Yun Michael Shim

Nature· October 2024

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Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain.
Elizabeth L Wagner, Jun-Sub Im, Stefano Sala, Maura I Nakahata, Terence E Imbery, Katherine Nimchuk

Elife· June 2023

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Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
Hyunsup Kim, Hyemin Choi, Jun-Sub Im, Soon-Young Park, Gwangsu Shin, Gyungmin Kim

J Biol Chem· October 2021

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RecQL4 tethering on the pre-replicative complex induces unscheduled origin activation and replication stress in human cells.
Gwangsu Shin, Dongsoo Jeong, Hyunsup Kim, Jun-Sub Im, Joon-Kyu Lee

J Biol Chem· November 2019

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ATM activation is impaired in human cells defective in RecQL4 helicase activity.
Soon-Young Park, Hyunsup Kim, Jun-Sub Im, Joon-Kyu Lee

Biochem Biophys Res Commun· February 2019

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ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks.
Kyung Yong Lee, Jun-Sub Im, Etsuko Shibata, Anindya Dutta

Mol Cell· October 2017

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RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells.
Jun-Sub Im, Soon-Young Park, Won-Ho Cho, Sung-Ho Bae, Jerard Hurwitz

Cell Cycle· December 2015

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MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.
Kyung Yong Lee, Jun-Sub Im, Etsuko Shibata, Jonghoon Park, Naofumi Handa

Nat Commun· July 2015

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ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks.
Jun-Sub Im, Mignon Keaton, Kyung Yong Lee, Pankaj Kumar, Jonghoon Park

Genes Dev· April 2014

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Human Primpol1: a novel guardian of stalled replication forks.
Jun-Sub Im, Kyung Yong Lee, Laura W Dillon, Anindya Dutta

EMBO Rep· December 2013

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Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells.
Soon-Young Park, Jun-Sub Im, Sung-Rye Park, Sang-Eun Kim, Hoe-Jeong Wang

Cell Cycle· February 2012

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Per3, a circadian gene, is required for Chk2 activation in human cells.
Jun-Sub Im, Bo-Hyeon Jung, Sang-Eun Kim, Kun-Ho Lee, Joon-Kyu Lee

FEBS Lett· December 2010

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Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins.
Jun-Sub Im, Sang-Hee Ki, Andrea Farina, Dong-Soo Jung, Jerard Hurwitz

Proc Natl Acad Sci U S A· September 2009

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ATR-dependent activation of p38 MAP kinase is responsible for apoptotic cell death in cells depleted of Cdc7.
Jun-Sub Im, Joon-Kyu Lee

J Biol Chem· September 2008

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Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.
Bo Yun Lee, Jung A Han, Jun Sub Im, Amelia Morrone, Kimberly Johung, Wim J Kleijer, Daniel DiMaio

Aging Cell· April 2006

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Induction of senescence-like state and suppression of telomerase activity through inhibition of HPV E6/E7 gene expression in cells immortalized by HPV16 DNA.
Chan Jae Lee, Eun Jung Suh, Hyun Tae Kang, Jun Sub Im, Soo Jong Um

Exp Cell Res· July 2002

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