Publications by authors named "Junji Magae"

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Analysis method of cellular stress caused by intermediate dose-rate irradiation using a cell lysate array technique.
Nobuhiro Morishima, Hiromitsu Ogata, Junji Magae, Yoshihiro Ito, Junya Kobayashi

Genes Cells· April 2023

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4-O-Methylascochlorin-Mediated BNIP-3 Expression Controls the Balance of Apoptosis and Autophagy in Cervical Carcinoma Cells.
Yuna Cho, Yun-Jeong Jeong, Kwon-Ho Song, Il-Kyung Chung, Junji Magae

Int J Mol Sci· December 2022

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4-O-methylascochlorin-stimulated HIF-1α expression induces the epithelial mesenchymal transition and cell survival in breast cancer cells.
Yun-Jeong Jeong, Soon-Kyung Hwang, Mi-Hee Yu, Yuna Cho, Kwon-Ho Song, Junji Magae

Toxicol In Vitro· June 2022

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4-O-methylascochlorin attenuates inflammatory responses induced by lipopolysaccharide in RAW 264.7 macrophages.
Hakseong Lim, Jun-Young Park, Fukushi Abekura, Hyunju Choi, Hee-Do Kim, Junji Magae

Int Immunopharmacol· January 2021

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Ascofuranone suppresses invasion and F-actin cytoskeleton organization in cancer cells by inhibiting the mTOR complex 1 signaling pathway.
Yun-Jeong Jeong, Soon-Kyung Hwang, Junji Magae, Young-Chae Chang

Cell Oncol (Dordr)· October 2020

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4-O-methylascochlorin activates autophagy by activating AMPK and suppressing c-Myc in glioblastoma.
Soon-Kyung Hwang, Si-Yoon Han, Yun-Jeong Jeong, Junji Magae, Young-Seuk Bae

J Biochem Mol Toxicol· October 2020

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Ascofuranone inhibits epidermal growth factor-induced cell migration by blocking epithelial-mesenchymal transition in lung cancer cells.
Hyo-Weon Kim, Yun-Jeong Jeong, Soon-Kyung Hwang, Yoon-Yub Park, Yung Hyun Choi, Junji Magae

Eur J Pharmacol· August 2020

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4--methylascochlorin stabilizes hypoxia-inducible factor-1 in a manner different from hydroxylase inhibition by iron chelating or substrate competition.
Junji Magae, Chiharu Furukawa, Shigefumi Kuwahara, Yun-Jeong Jeong, Hiroo Nakajima

Biosci Biotechnol Biochem· December 2019

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Ascochlorin induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages.
Junyoung Park, Hee-Do Kim, Sook-Hyun Lee, Choong-Hwan Kwak, Young-Chae Chang, Junji Magae

J Ethnopharmacol· July 2019

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4-O-Methylascochlorin inhibits the prolyl hydroxylation of hypoxia-inducible factor-1α, which is attenuated by ascorbate.
Tetsuya Kondo, Kenji Takeda, Ryo Muko, Akihiro Ito, Young-Chae Chang, Junji Magae

J Antibiot (Tokyo)· May 2019

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[Vinorelbine, a Microtubule Toxin, Induces Apoptosis and Polyploidy in MX-1, a Human Triple-Negative Breast Cancer Cell Line].
Hiroo Nakajima, Chiharu Furukawa, Junji Magae

Gan To Kagaku Ryoho· March 2019

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Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1α expression.
Ji-Young Seok, Yun-Jeong Jeong, Soon-Kyung Hwang, Cheorl-Ho Kim, Junji Magae

J Cell Mol Med· December 2018

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Suppression of c-Myc enhances p21 -mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin.
Yun-Jeong Jeong, Hyang-Sook Hoe, Hyun-Ji Cho, Kwan-Kyu Park, Dae-Dong Kim, Junji Magae

J Cell Biochem· February 2018

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Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy.
Jason Chua Min-Wen, Benjamin Chua Yan-Jiang, Srishti Mishra, Xiaoyun Dai, Junji Magae

Adv Protein Chem Struct Biol· October 2017

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Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages.
Jun-Young Park, Tae-Wook Chung, Yun-Jeong Jeong, Choong-Hwan Kwak, Sun-Hyung Ha, Junji Magae

PLoS One· August 2017

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Delayed Growth Suppression and Radioresistance Induced by Long-Term Continuous Gamma Irradiation.
Hiroo Nakajima, Chiharu Furukawa, Young-Chae Chang, Hiromitsu Ogata, Junji Magae

Radiat Res· August 2017

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Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma.
Xiaoyun Dai, Kwang Seok Ahn, Ling Zhi Wang, Chulwon Kim, Amudha Deivasigamni, Junji Magae

Mol Cancer Ther· December 2016

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Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.
Jae-Moon Shin, Yun-Jeong Jeong, Hyun-Ji Cho, Junji Magae, Young-Seuk Bae

Apoptosis· May 2016

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Erratum to: Suppression of c-Myc induces apoptosis via an AMPK/mTOR-dependent pathway by 4-O-methyl-ascochlorin in leukemia cells.
Jae-Moon Shin, Yun-Jeong Jeong, Hyun-Ji Cho, Junji Magae, Young-Seuk Bae

Apoptosis· May 2016

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Anti-Inflammatory Effect of Ascochlorin in LPS-Stimulated RAW 264.7 Macrophage Cells Is Accompanied With the Down-Regulation of iNOS, COX-2 and Proinflammatory Cytokines Through NF-κB, ERK1/2, and p38 Signaling Pathway.
Sook-Hyun Lee, Choong-Hwan Kwak, Sung-Kyun Lee, Sun-Hyung Ha, Junyoung Park, Junji Magae

J Cell Biochem· April 2016

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4-O-methylascochlorin suppresses differentiation of 3T3-L1 preadipocytes by inhibiting PPARγ expression through regulation of AMPK/mTOR signaling pathways.
Mihyun Kim, Hyun-Ji Cho, Yun-Jeong Jeong, Il-Kyung Chung, Junji Magae

Arch Biochem Biophys· October 2015

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Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.
Xiaoyun Dai, Kwang Seok Ahn, Chulwon Kim, Kodappully Sivaraman Siveen, Tina H Ong, Junji Magae

Mol Oncol· April 2015

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Ascofuranone suppresses EGF-induced HIF-1α protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells.
Yun-Jeong Jeong, Hyun-Ji Cho, Junji Magae, In-Kyu Lee, Keun-Gyu Park

Toxicol Appl Pharmacol· December 2013

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Ionizing radiation leads to the replacement and de novo production of colonic Lgr5(+) stem cells.
Kensuke Otsuka, Nobuyuki Hamada, Junji Magae, Hideki Matsumoto, Yuko Hoshi

Radiat Res· June 2013

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Prolongation of life span in the accelerated aging klotho mouse model, by low-dose-rate continuous γ irradiation.
Takaharu Nomura, Kazuo Sakai, Hiromitsu Ogata, Junji Magae

Radiat Res· June 2013

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