Publications by authors named "Junko Hashimoto"

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JBIR-160-166 Obtained from the Heterologous Expression of a Cryptic Gene Cluster in .
Takehiro Nishimura, Kei Kudo, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto

Org Lett· December 2025

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Effects of blood flow restriction training using plural parallel cuff on walking functions of older people.
Masahiro Matsunaga, Masahiro Kimura, Junko Hashimoto, Yusuke Tominari, Keiko Ishii

Neuro Endocrinol Lett· September 2025

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Isolation and structure determination of streptospherins B-F, novel cancer stem cell inhibitors, produced by Streptomyces sp. KUSC-240.
Morihiro Shibasaki, Hiroaki Ikeda, Ami Mimura, Junko Hashimoto, Taiki Suo

J Antibiot (Tokyo)· August 2025

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Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds.
Kei Kudo, Takehiro Nishimura, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto

J Antibiot (Tokyo)· May 2024

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Isolation and Structure Elucidation of JBIR-157, a Skeletally Novel Aromatic Polyketide Produced by the Heterologous Expression of a Cryptic Gene Cluster.
Takehiro Nishimura, Kei Kudo, Miho Izumikawa, Ikuko Kozone, Junko Hashimoto

Chem Pharm Bull (Tokyo)· May 2024

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In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G -Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont.
Takuya Hashimoto, Hikaru Suenaga, Keita Amagai, Junko Hashimoto, Ikuko Kozone

Angew Chem Int Ed Engl· March 2024

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Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics.
Fumitaka Kudo, Kosuke Kishikawa, Kazuma Tsuboi, Takafusa Kido, Takeo Usui, Junko Hashimoto

Chembiochem· March 2023

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Mechanism of -Adenosyl-l-methionine -Methylation by Cobalamin-dependent Radical -Adenosyl-l-methionine Methylase in 1-Amino-2-methylcyclopropanecarboxylic Acid Biosynthesis.
Fumitaka Kudo, Atsushi Minato, Shusuke Sato, Nayuta Nagano, Chitose Maruyama, Junko Hashimoto

Org Lett· December 2022

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New azodyrecins identified by a genome mining-directed reactivity-based screening.
Atina Rizkiya Choirunnisa, Kuga Arima, Yo Abe, Noritaka Kagaya, Kei Kudo, Junko Hashimoto

Beilstein J Org Chem· August 2022

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A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme.
Kenichi Matsuda, Kuga Arima, Satoko Akiyama, Yuito Yamada, Yo Abe, Junko Hashimoto

J Am Chem Soc· July 2022

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Complete Genome Sequence of sp. Strain TBR-22.
Kyosuke Yamamoto, Yasuko Yoneda, Ayaka Makino, Yasuhiro Tanaka, Xian-Ying Meng, Junko Hashimoto

Microbiol Resour Announc· February 2022

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Draft Genome Sequence of Strain F-183.
Kyosuke Yamamoto, Yasuko Yoneda, Ayaka Makino, Yasuhiro Tanaka, Xian-Ying Meng, Junko Hashimoto

Microbiol Resour Announc· January 2022

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Primary leiomyoma of the ureter: a case report.
Shingo Morinaga, Shigeyuki Aoki, Motoi Tobiume, Genya Nishikawa, Hiroyuki Muramatsu, Junko Hashimoto

J Med Case Rep· August 2021

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An Atypical Arginine Dihydrolase Involved in the Biosynthesis of Cyclic Hexapeptide Longicatenamides.
Chao Liu, Junko Hashimoto, Kei Kudo, Kazuo Shin-Ya, Hideaki Kakeya

Chem Asian J· June 2021

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A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster.
Takuya Hashimoto, Junko Hashimoto, Noritaka Kagaya, Takehiro Nishimura, Hikaru Suenaga

J Antibiot (Tokyo)· May 2021

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Identification of functional cytochrome P450 and ferredoxin from Streptomyces sp. EAS-AB2608 by transcriptional analysis and their heterologous expression.
Shinya Okubo, Eri Ena, Akifumi Okuda, Ikuko Kozone, Junko Hashimoto

Appl Microbiol Biotechnol· May 2021

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Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase.
Kei Kudo, Takehiro Nishimura, Ikuko Kozone, Junko Hashimoto, Noritaka Kagaya

Sci Rep· May 2021

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Novel Plant-Associated Promotes Growth of Common Floating Aquatic Plants, Duckweeds.
Yasuko Yoneda, Kyosuke Yamamoto, Ayaka Makino, Yasuhiro Tanaka, Xian-Ying Meng, Junko Hashimoto

Microorganisms· May 2021

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A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900.
Reiko Ueoka, Junko Hashimoto, Ikuko Kozone, Takuya Hashimoto, Kei Kudo

Biosci Biotechnol Biochem· March 2021

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Heterologous Expression of the Biosynthetic Gene Cluster for Verticilactam and Identification of Analogues.
Toshihiko Nogawa, Atsutaka Terai, Keita Amagai, Junko Hashimoto, Yushi Futamura

J Nat Prod· December 2020

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Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin.
Takuya Hashimoto, Ikuko Kozone, Junko Hashimoto, Hikaru Suenaga, Manabu Fujie

J Antibiot (Tokyo)· September 2020

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In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives.
Kei Kudo, Takuya Hashimoto, Junko Hashimoto, Ikuko Kozone, Noritaka Kagaya

Nat Commun· August 2020

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-Methylation of -adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium.
Chitose Maruyama, Yukiko Chinone, Shusuke Sato, Fumitaka Kudo, Kosuke Ohsawa, Junko Hashimoto

Biomolecules· May 2020

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Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908.
Takuya Hashimoto, Ikuko Kozone, Junko Hashimoto, Reiko Ueoka, Noritaka Kagaya

J Antibiot (Tokyo)· March 2020

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An Unusual Extender Unit Is Incorporated into the Modular Polyketide Synthase of Scopranones Biosynthesis.
Ayumu Demachi, Ryuji Uchida, Shiho Arima, Tohru Nagamitsu, Junko Hashimoto

Biochemistry· December 2019

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