Publications by authors named "Junping Kou"

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Xinqingning tablet attenuates ischemic stroke complicated by gut dysbiosis through regulating the miR-126-driven gut-brain axis.
Shuaishuai Gong, Yuanhao Xu, Ruihao Zhao, Junhe Yu, Liangying Bao, Junping Kou

Phytomedicine· November 2025

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6‴-Feruloylspinosin ameliorates pressure overload-induced heart failure with comorbid insomnia through the activation of RORα.
Yan Yan, Shuaishuai Gong, Minhui Sun, Zhekai Huang, Lan Gao, Junping Kou

Br J Pharmacol· November 2025

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Qin Gui Huo Luo Oral Liquid Attenuates Blood-Brain Barrier Dysfunction after Cerebral Ischemia-Reperfusion Injury in Mice via the Regulation of the PI3K/AKT/FOXO3A Signaling Pathway.
Xueyu Ling, Liangying Bao, Yuanhao Xu, Shuaishuai Gong, Junping Kou

Biol Pharm Bull· October 2025

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The role of ROCK1/MLC/NMMHC IIA-actin signaling in ischemic stroke-induced blood-brain barrier disruption: implications for therapeutic intervention.
Liangying Bao, Yuanhao Xu, Yuchuan Ren, Yujie Dai, Junhe Yu, Junping Kou

Cell Mol Life Sci· October 2025

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Endothelial NMMHC IIA dissociation from PAR1 activates the CREB3/ARF4 signaling in thrombin-mediated intracerebral hemorrhage.
Yujie Dai, Liangying Bao, Juan Huang, Miling Zhang, Junhe Yu, Junping Kou

J Adv Res· September 2025

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Salvianolic acid A ameliorates sepsis through inhibiting inflammation via binding STING and modulating TBK1/IRF3 signaling pathway.
Xiangying Qin, Liyuan Zhang, Jiahui Tang, Fan Zhang, Ling Zhang, Junping Kou

Int Immunopharmacol· September 2025

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Ginsenoside Rh1 mitigates mitochondrial dysfunction induced by myocardial ischaemia through its novel role as a sirtuin 3 activator.
Shuaishuai Gong, Hong Chen, Shuhua Fang, Mengyu Li, Jingui Hu, Junping Kou

Br J Pharmacol· July 2025

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Silibinin alleviates acute liver failure by modulating AKT/GSK3β/Nrf2/GPX4 pathway.
Yue Li, Hailan Li, Minhui Sun, Hong Chen, Yao Xiao, Junping Kou

Naunyn Schmiedebergs Arch Pharmacol· June 2025

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Astragali Radix-Notoginseng Radix et Rhizoma medicine pair prevents cardiac remodeling by improving mitochondrial dynamic balance.
Pingping Lin, Hong Chen, Zekun Cui, Boyang Yu, Junping Kou

Chin J Nat Med· January 2025

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Enhanced effect of limb remote ischemic postconditioning combined with paeoniflorin on alleviating cerebral ischemic injury via neutrophil NADPH pathway.
Qi Wu, Wenxuan Que, Jiangwei Zhang, Xun Chen, Min Wang, Junping Kou

Brain Res Bull· August 2024

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Preventive and Therapeutic Effects of Crocetin in Rats with Heart Failure.
Renqiang Ma, Sijia Li, Qingmei Mo, Xiaojuan Chen, Yan Liang, Junping Kou

Pharmaceuticals (Basel)· April 2024

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Inhibition of OAT1/3 and CMPF uptake attenuates myocardial ischemia-induced chronic heart failure via decreasing fatty acid oxidation and the therapeutic effects of ruscogenin.
Qiong Lai, Xiaozhou Zhu, Lu Zhang, Junping Kou, Fuming Liu

Transl Res· November 2023

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Ruscogenin timing administration mitigates cerebral ischemia-reperfusion injury through regulating circadian genes and activating Nrf2 pathway.
Sanli Zhang, Yan Yu, Mingyue Sheng, Xun Chen, Qi Wu, Junping Kou

Phytomedicine· November 2023

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Ruscogenin Alleviates Myocardial Ischemia via Myosin IIA-Dependent Mitochondrial Fusion and Fission Balance.
Jin-Cheng Liu, Qing-Fei Zhao, Ling Zhang, Bo-Yang Yu, Fang Li, Jun-Ping Kou

Am J Chin Med· October 2023

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Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca pathways.
Zekun Cui, Lifei Gu, Tao Liu, Yining Liu, Boyang Yu, Junping Kou

Eur J Pharmacol· October 2023

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Phosphorylation of MAP 1A regulates hyperphosphorylation of Tau in Alzheimer's disease model.
Biao Cai, Nan Shao, Ting Ye, Peng Zhou, Wenwen Si, Junping Kou

Neuropathol Appl Neurobiol· October 2023

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Ruscogenin ameliorates dasatinib-induced intestinal barrier dysfunction via ErbB4/YAP and ROCK/MLC pathways.
Juan Huang, Jianhao Zhou, Yujie Dai, Yuankai Liu, Fang Li, Junping Kou

J Nat Med· September 2023

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Background and roles: myosin in autoimmune diseases.
Longsheng Fu, Yonghui Zou, Boyang Yu, Daojun Hong, Teng Guan, Junping Kou

Front Cell Dev Biol· August 2023

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Inhibition of KMO Ameliorates Myocardial Ischemia Injury via Maintaining Mitochondrial Fusion and Fission Balance.
Qiong Lai, Lingling Wu, Shuhong Dong, Xiaozhou Zhu, Zhaoyang Fan, Junping Kou

Int J Biol Sci· July 2023

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QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Lingling Wu, Zhaoyang Fan, Lifei Gu, Jincheng Liu, Zekun Cui, Junping Kou

J Ethnopharmacol· May 2023

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Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca pathways in heart failure.
Shiyao Wan, ZeKun Cui, Lingling Wu, Fan Zhang, Tao Liu, Junping Kou

Redox Biol· April 2023

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Rev-erbα agonist SR9009 protects against cerebral ischemic injury through mechanisms involving Nrf2 pathway.
Mingyue Sheng, Xun Chen, Yan Yu, Qi Wu, Junping Kou

Front Pharmacol· March 2023

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Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy.
Jingui Hu, Tao Liu, Fei Fu, Zekun Cui, Qiong Lai, Junping Kou

J Transl Med· October 2022

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A tRNA-derived fragment of ginseng protects heart against ischemia/reperfusion injury via targeting the lncRNA MIAT/VEGFA pathway.
Kua Hu, Tong-Meng Yan, Kai-Yue Cao, Fang Li, Xiao-Rong Ma, Jun-Ping Kou

Mol Ther Nucleic Acids· September 2022

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Ginsenoside Rb1 improves brain, lung, and intestinal barrier damage in middle cerebral artery occlusion/reperfusion (MCAO/R) micevia the PPARγ signaling pathway.
Lin-Jie Su, Yu-Chuan Ren, Zhuo Chen, Hui-Fen Ma, Fan Zheng, Jun-Ping Kou

Chin J Nat Med· August 2022

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