Publications by authors named "Junsheng Xue"

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Drug Repositioning of Pegbing® for Essential Thrombocythemia: Insights from PK/PD Modeling and Extrapolation.
Weizhe Jian, Yalin Yin, Rong Chen, Junsheng Xue, Jianbo Gu

Clin Pharmacol Ther· January 2026

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Population Pharmacokinetic Model of Pegbing in Healthy Subjects and Chronic Hepatitis B Patients.
Weizhe Jian, Yalin Yin, Rong Chen, Pingyao Luo, Tianyu Wang, Junsheng Xue

CPT Pharmacometrics Syst Pharmacol· December 2025

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A Simplified Three-Tailed N-Alkyl Phosphoramidate Lipid Platform Enables Inguinal Adipose-Accumulated mRNA Delivery for Anti-Obesity Therapy.
Bin Ma, Yunxuan Liu, Huijuan Zhang, Yian Fang, Yizhe Xue, Junsheng Xue

Adv Sci (Weinh)· December 2025

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PK/PD modeling of the effect of Escitalopram combined with Docetaxel in the treatment of breast cancer with depression in mice.
Tian-Yu Wang, Jun-Sheng Xue, Lei Cai, Chen Liu, Tian-Yu Bao

J Pharm Sci· November 2025

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Hepatitis surface B antigen clearance induced by long-term tenofovir disoproxil fumarate monotherapy in chronic hepatitis B treatment: a meta-analysis and longitudinal modeling analysis.
Weizhe Jian, Yalin Yin, Junsheng Xue, Rong Chen, Jingwen Feng

Virol J· May 2025

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Longitudinal and time-to-event modeling for the survival of advanced pancreatic ductal adenocarcinoma patients.
Qing-Yu Yao, Ping-Yao Luo, Ling-Xiao Xu, Rong Chen, Jun-Sheng Xue

Acta Pharmacol Sin· March 2025

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Model-based analysis for investigating the impact of tumor size, lymphocyte and neutrophil on the survival of breast cancer 4T1 tumor-bearing mice.
Qing-Yu Yao, Xin-Yu Hou, Wei-Zhe Jian, Tian-Yu Wang, Ping-Yao Luo, Jun-Sheng Xue

Toxicol Appl Pharmacol· January 2025

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Real-Time Multi-Person Video Synthesis with Controllable Prior-Guided Matting.
Aoran Chen, Hai Huang, Yueyan Zhu, Junsheng Xue

Sensors (Basel)· April 2024

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An integrated PK/PD model investigating the impact of tumor size and systemic safety on animal survival in SW1990 pancreatic cancer xenograft.
Qing-Yu Yao, Jun Zhou, Ye Yao, Jun-Sheng Xue, Yu-Chen Guo

Acta Pharmacol Sin· February 2023

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Application of a count data model to evaluate the anti-metastatic efficacy of QAP14 in 4T1 breast cancer allografts.
Yuchen Guo, Ling Yong, Qingyu Yao, Mengyi Han, Junsheng Xue

J Theor Biol· January 2023

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Starting dose selection of palbociclib in Chinese patients with breast cancer based on population kinetic-pharmacodynamic model of neutropenia.
Weizhe Jian, Junsheng Xue, Qingyu Yao, Rong Chen, Ye Yao

Cancer Chemother Pharmacol· December 2022

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Author Correction: QAP14 suppresses stemness and metastasis of breast cancer via the activation of dopamine D1 receptor.
Ling Yong, Ye Yao, Guo-Shu Chen, Xiao-Xue Yan, Yu-Chen Guo, Jun-Sheng Xue

Acta Pharmacol Sin· July 2022

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QAP14 suppresses breast cancer stemness and metastasis via activation of dopamine D1 receptor.
Ling Yong, Ye Yao, Guo-Shu Chen, Xiao-Xue Yan, Yu-Chen Guo, Jun-Sheng Xue

Acta Pharmacol Sin· April 2022

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Mechanistic prediction of first-in-human dose for bispecific CD3/EpCAM T-cell engager antibody M701, using an integrated PK/PD modeling method.
Ling Song, Junsheng Xue, Jing Zhang, Si Li, Dongyang Liu

Eur J Pharm Sci· March 2021

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Important roles of estrogen receptor alpha in tumor progression and anti-estrogen therapy of pancreatic ductal adenocarcinoma.
Junsheng Xue, Ye Yao, Qingyu Yao, Xiuyun Tian, Yaoyao Feng

Life Sci· November 2020

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Prediction of Human Pharmacokinetics and Clinical Effective Dose of SI-B001, an EGFR/HER3 Bi-specific Monoclonal Antibody.
Junsheng Xue, Daming Kong, Ye Yao, Liang Yang, Qingyu Yao

J Pharm Sci· October 2020

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Development and validation of a highly sensitive HPLC-MS/MS method for the QAP14, a novel potential anti-cancer agent, in rat plasma and its application to a pharmacokinetic study.
Yuchen Guo, Qingyu Yao, Daming Kong, Junsheng Xue, Ling Yong

J Pharm Biomed Anal· September 2020

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Dexamethasone inhibits pancreatic tumor growth in preclinical models: Involvement of activating glucocorticoid receptor.
Ye Yao, Qing-Yu Yao, Jun-Sheng Xue, Xiu-Yun Tian, Qi-Ming An

Toxicol Appl Pharmacol· August 2020

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Development and validation of a LC-MS/MS method for simultaneous determination of six glucocorticoids and its application to a pharmacokinetic study in nude mice.
Qingyu Yao, Yuchen Guo, Junsheng Xue, Daming Kong, Jian Li

J Pharm Biomed Anal· February 2020

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Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer.
Qing-Yu Yao, Jian Li, Rong Chen, Ye Yao, Jun-Sheng Xue

Acta Pharmacol Sin· December 2019

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N-arylpiperazine-containing compound (C2): An enhancer of sunitinib in the treatment of pancreatic cancer, involving D1DR activation.
Hong Su, Zixi Xue, Yaoyao Feng, Ying Xie, Bo Deng, Junsheng Xue

Toxicol Appl Pharmacol· December 2019

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Dopamine D receptor agonists inhibit lung metastasis of breast cancer reducing cancer stemness.
Liang Yang, Ye Yao, Ling Yong, Yaoyao Feng, Hong Su, Junsheng Xue

Eur J Pharmacol· September 2019

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Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer.
Jian Li, Qing-Yu Yao, Jun-Sheng Xue, Li-Jie Wang, Yin Yuan

Acta Pharmacol Sin· September 2017

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Pharmacokinetic-Pharmacodynamic Modeling of the Anti-Tumor Effect of Sunitinib Combined with Dopamine in the Human Non-Small Cell Lung Cancer Xenograft.
Fangran Hao, Siyuan Wang, Xiao Zhu, Junsheng Xue, Jingyun Li

Pharm Res· February 2017

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