Publications by authors named "Junya Azumi"

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Combination of 3-(Trihydroxygermyl)propanoic Acid (THGP) and Lipopolysaccharide Promotes Macrophage Differentiation to M1, and Antitumor Activity.
Junya Azumi, Tomoya Takeda, Yasuhiro Shimada, Hisashi Aso, Hiroyuki Inagawa

Anticancer Res· August 2025

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The Organogermanium Compound 3-(trihydroxygermyl)propanoic Acid Exerts Anti-Inflammatory Effects via Adenosine-NR4A2 Signaling.
Junya Azumi, Tomoya Takeda, Shunya Shibata, Yasuhiro Shimada, Hisashi Aso

Int J Mol Sci· March 2025

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Organogermanium: Potential beneficial effects on the cardiovascular system.
Kunihiko Aizawa, Takashi Nakamura, Yasuhiro Shimada, Tomoya Takeda, Junya Azumi

Physiol Rep· February 2025

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Organogermanium, Ge-132, promotes the clearance of senescent red blood cells via macrophage-mediated phagocyte activation.
Tomoya Takeda, Junya Azumi, Mika Masaki, Takae Nagasawa, Yasuhiro Shimada

Heliyon· January 2024

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Organogermanium THGP Induces Differentiation into M1 Macrophages and Suppresses the Proliferation of Melanoma Cells via Phagocytosis.
Junya Azumi, Tomoya Takeda, Yasuhiro Shimada, Tao Zhuang, Yoshihiko Tokuji

Int J Mol Sci· January 2023

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The Organogermanium Compound 3-(Trihydroxygermyl) Propanoic Acid (THGP) Suppresses Inflammasome Activation Via Complexation with ATP.
Junya Azumi, Yasuhiro Shimada, Tomoya Takeda, Hisashi Aso, Takashi Nakamura

Int J Mol Sci· November 2022

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Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts.
Tomoya Takeda, Sota Doiyama, Junya Azumi, Yasuhiro Shimada, Yoshihiko Tokuji

Sci Rep· September 2019

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The Organogermanium Compound THGP Suppresses Melanin Synthesis via Complex Formation with L-DOPA on Mushroom Tyrosinase and in B16 4A5 Melanoma Cells.
Junya Azumi, Tomoya Takeda, Yasuhiro Shimada, Hisashi Aso, Takashi Nakamura

Int J Mol Sci· September 2019

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Expression of Cancer Stem Cell-associated mRNA Serves as Prognostic Marker for Hepatocellular Carcinoma.
Tomohiko Sakabe, Junya Azumi, Yoshihisa Umekita, Kan Toriguchi, Etsuro Hatano

Anticancer Res· September 2017

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WNT/β-Catenin Signaling Inhibitor IC-2 Suppresses Sphere Formation and Sensitizes Colorectal Cancer Cells to 5-Fluorouracil.
Shoichi Urushibara, Toshiaki Tsubota, Ryoma Asai, Junya Azumi, Keigo Ashida

Anticancer Res· August 2017

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A Novel Small-molecule WNT Inhibitor, IC-2, Has the Potential to Suppress Liver Cancer Stem Cells.
Kenzo Seto, Tomohiko Sakabe, Noriko Itaba, Junya Azumi, Hiroyuki Oka

Anticancer Res· July 2017

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CD117 expression is a predictive marker for poor prognosis in patients with non-small cell lung cancer.
Tomohiko Sakabe, Junya Azumi, Tomohiro Haruki, Yoshihisa Umekita, Hiroshige Nakamura

Oncol Lett· May 2017

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Impact of Preferentially Expressed Antigen of Melanoma on the Prognosis of Hepatocellular Carcinoma.
Kenji Oyama, Keita Kanki, Hiroki Shimizu, Yohei Kono, Junya Azumi

Gastrointest Tumors· March 2017

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Prognostic relevance of miR-137 in patients with hepatocellular carcinoma.
Tomohiko Sakabe, Junya Azumi, Yoshihisa Umekita, Kan Toriguchi, Etsuro Hatano

Liver Int· February 2017

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miR-181a induces sorafenib resistance of hepatocellular carcinoma cells through downregulation of RASSF1 expression.
Junya Azumi, Toshiaki Tsubota, Tomohiko Sakabe, Goshi Shiota

Cancer Sci· September 2016

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Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population.
Satoshi Yokogi, Toshiaki Tsubota, Keita Kanki, Junya Azumi, Noriko Itaba

Yonago Acta Med· June 2016

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Identification of the small molecule compound which induces hepatic differentiation of human mesenchymal stem cells.
Noriko Itaba, Tomohiko Sakabe, Keita Kanki, Junya Azumi, Hiroki Shimizu

Regen Ther· December 2015

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Identification of the genes chemosensitizing hepatocellular carcinoma cells to interferon-α/5-fluorouracil and their clinical significance.
Tomohiko Sakabe, Hiroyuki Tsuchiya, Keita Kanki, Junya Azumi, Kazue Gonda

PLoS One· August 2013

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Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation.
Remina Ikeda, Kyoko Ishii, Yoshiko Hoshikawa, Junya Azumi, Yuta Arakaki

Inflamm Res· June 2011

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c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells.
Yoshiko Hoshikawa, Keita Kanki, An Afida Ashla, Yuta Arakaki, Junya Azumi

Cancer Sci· May 2011

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