Publications by authors named "Junya Qu"

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Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors.
Dai-Shi Su, Junya Qu, Mark Schulz, Chuck W Blackledge, Hongyi Yu

ACS Med Chem Lett· February 2020

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Discovery of a Novel 2,6-Disubstituted Glucosamine Series of Potent and Selective Hexokinase 2 Inhibitors.
Hong Lin, Jin Zeng, Ren Xie, Mark J Schulz, Rosanna Tedesco, Junya Qu, Jacques Briand

ACS Med Chem Lett· March 2016

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Structure-guided optimization of small molecule c-Abl activators.
Xuan Hong, Ping Cao, Yoshiaki Washio, Graham Simpson, Nino Campobasso, Junya Qu

J Comput Aided Mol Des· February 2014

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[3a,4]-Dihydropyrazolo[1,5a]pyrimidines: Novel, Potent, and Selective Phosphatidylinositol-3-kinase β Inhibitors.
Hongyi Yu, Michael L Moore, Karl Erhard, Mary Ann Hardwicke, Hong Lin, Junya Qu

ACS Med Chem Lett· February 2013

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Rational Design, Synthesis, and SAR of a Novel Thiazolopyrimidinone Series of Selective PI3K-beta Inhibitors.
Hong Lin, Mark J Schulz, Ren Xie, Jin Zeng, Juan I Luengo, Michael D Squire, Junya Qu

ACS Med Chem Lett· July 2012

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Discovery and characterization of a cell-permeable, small-molecule c-Abl kinase activator that binds to the myristoyl binding site.
Jingsong Yang, Nino Campobasso, Mangatt P Biju, Kelly Fisher, Xiao-Qing Pan, Junya Qu

Chem Biol· February 2011

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Facile synthesis of 6-aryl 5-N-substituted pyridazinones: microwave-assisted Suzuki-Miyaura cross coupling of 6-chloropyridazinones.
Ping Cao, Junya Qu, George Burton, Ralph A Rivero

J Org Chem· September 2008

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2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead.
Ellen W Baxter, Kelly A Conway, Ludo Kennis, François Bischoff, Marc H Mercken, Junya Qu

J Med Chem· September 2007

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