Publications by authors named "Jure Acimovic"

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Training in Systems Approaches for the Next Generation of Life Scientists and Medical Doctors.
Damjana Rozman, Jure Acimovic, Bernd Schmeck

Methods Mol Biol· October 2016

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Mouse genotypes drive the liver and adrenal gland clocks.
Rok Košir, Uršula Prosenc Zmrzljak, Anja Korenčič, Peter Juvan, Jure Ačimovič

Sci Rep· August 2016

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Cytochrome P450 metabolism of the post-lanosterol intermediates explains enigmas of cholesterol synthesis.
Jure Ačimovič, Sandeep Goyal, Rok Košir, Marko Goličnik, Martina Perše

Sci Rep· June 2016

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Strategies for structuring interdisciplinary education in Systems Biology: an European perspective.
Marija Cvijovic, Thomas Höfer, Jure Aćimović, Lilia Alberghina, Eivind Almaas

NPJ Syst Biol Appl· May 2016

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Cholesterol, oxysterol, triglyceride, and coenzyme Q homeostasis in ALS. Evidence against the hypothesis that elevated 27-hydroxycholesterol is a pathogenic factor.
Anna Wuolikainen, Jure Acimovic, Anita Lövgren-Sandblom, Paolo Parini, Peter M Andersen

PLoS One· December 2015

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Statin-induced Myopathy and Ubiquinone Levels in Serum - Results from a Prospective, Observational Study.
Ilona Skilving, Jure Acimovic, Anders Rane, Marie-Louise Ovesjö, Linda Björkhem-Bergman

Basic Clin Pharmacol Toxicol· August 2015

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Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.
Jure Acimovic, Anita Lövgren-Sandblom, Maria Olin, Zeina Ali, Maura Heverin

PLoS One· February 2014

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Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51).
Rok Keber, Jure Ačimovič, Gregor Majdič, Helena Motaln, Damjana Rozman

J Lipid Res· June 2013

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On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(-/-) mice.
Zeina Ali, Maura Heverin, Maria Olin, Jure Acimovic, Anita Lövgren-Sandblom

J Lipid Res· April 2013

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Steroidal triterpenes of cholesterol synthesis.
Jure Ačimovič, Damjana Rozman

Molecules· April 2013

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The anti-carcinogenic effect of statins in a rat model correlates with levels and synthesis of ubiquinone.
Jure Acimovic, Anita Lövgren-Sandblom, Lennart C Eriksson, Linda Björkhem-Bergman

Biochem Biophys Res Commun· August 2012

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Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland--involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1.
Rok Košir, Ursula Prosenc Zmrzljak, Tanja Bele, Jure Acimovic, Martina Perse

FEBS J· May 2012

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Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome.
Rok Keber, Helena Motaln, Kay D Wagner, Nataša Debeljak, Minoo Rassoulzadegan

J Biol Chem· August 2011

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Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice.
Jure Ačimovič, Rok Košir, Damijana Kastelec, Martina Perše, Gregor Majdič

Biochem Biophys Res Commun· May 2011

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Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis.
Jure Acimovic, Tina Korosec, Matej Seliskar, Ingemar Bjorkhem, Katalin Monostory

Drug Metab Dispos· January 2011

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Determination of reference genes for circadian studies in different tissues and mouse strains.
Rok Kosir, Jure Acimovic, Marko Golicnik, Martina Perse, Gregor Majdic

BMC Mol Biol· August 2010

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Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation.
Linda Björkhem-Bergman, Jure Acimovic, Ulla-Britta Torndal, Paolo Parini, Lennart C Eriksson

Anticancer Res· April 2010

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Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells.
Jure Acimovic, Anita Lövgren-Sandblom, Katalin Monostory, Damjana Rozman, Marko Golicnik

J Chromatogr B Analyt Technol Biomed Life Sci· July 2009

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Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent.
Katalin Monostory, Jean-Marc Pascussi, Pál Szabó, Manna Temesvári, Krisztina Köhalmy, Jure Acimovic

Drug Metab Dispos· February 2009

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CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver.
Jure Acimovic, Martina Fink, Denis Pompon, Ingemar Bjorkhem, Jun Hirayama

Biochem Biophys Res Commun· November 2008

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Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).
Tina Korosec, Jure Acimovic, Matej Seliskar, Darko Kocjan, Klementina Fon Tacer

Bioorg Med Chem· January 2008

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Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene.
Martina Fink, Jure Acimovic, Tadeja Rezen, Natasa Tansek, Damjana Rozman

Endocrinology· December 2005

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