Publications by authors named "Justin D Boyd"

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Tau-targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy.
Christopher M Brown, Jeanne K Brooks, Louise Kelly, Madeline M Vroom, Matthew Longo, Justin D Boyd

Brain Pathol· December 2025

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Preclinical characterization of an active immunotherapy targeting calcitonin gene-related peptide.
Justin D Boyd, Shixia Wang, Hsiao-Wen Lin, Yueh-Ting Hsieh, Yu Shuang Sun

Commun Med (Lond)· April 2025

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Target engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial.
Pepijn Eijsvogel, Pinaki Misra, Luis Concha-Marambio, Justin D Boyd, Shuang Ding

Nat Med· September 2024

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VXX-401, a novel anti-PCSK9 vaccine, reduces LDL-C in cynomolgus monkeys.
Madeline M Vroom, Hanxin Lu, Maggie Lewis, Brett A Thibodeaux, Jeanne K Brooks, Justin D Boyd

J Lipid Res· February 2024

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Optimizing the Cell Painting assay for image-based profiling.
Beth A Cimini, Srinivas Niranj Chandrasekaran, Maria Kost-Alimova, Lisa Miller, Amy Goodale, Justin D Boyd

Nat Protoc· July 2023

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GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer's Disease.
Sarah M Connor, Mamunur Rashid, Katie J Ryan, Kruti Patel, Justin D Boyd

Front Cell Neurosci· May 2022

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Advances in High-Content Imaging and Informatics: A Joint Special Collection with Society for Biomolecular Imaging and Informatics and SLAS.
Justin D Boyd, Ann F Hoffman

SLAS Discov· October 2021

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Image-based profiling for drug discovery: due for a machine-learning upgrade?
Srinivas Niranj Chandrasekaran, Hugo Ceulemans, Justin D Boyd, Anne E Carpenter

Nat Rev Drug Discov· February 2021

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Society of Biomolecular Imaging and Informatics High-Content Screening/High-Content Analysis Preclinical Translational Imaging Colloquium: How Emerging Technologies in Disease Models, High-Content Imaging, and Data Analytics Are Changing Our Approach to Drug Discovery.
Justin D Boyd, Ann F Hoffman, David Gebhard

Assay Drug Dev Technol· January 2019

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Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.
Jason Schapansky, Saurabh Khasnavis, Mark P DeAndrade, Jonathan D Nardozzi, Samuel R Falkson, Justin D Boyd

Neurobiol Dis· March 2018

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Oxytocin alters cell fate selection of rat neural progenitor cells in vitro.
Arvind Palanisamy, Ramaswamy Kannappan, Zhiqiang Xu, Audrey Martino, Matthew B Friese, Justin D Boyd

PLoS One· February 2018

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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Katie J Ryan, Charles C White, Kruti Patel, Jishu Xu, Marta Olah, Justin D Boyd

Sci Transl Med· December 2017

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Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro.
Arvind Palanisamy, Matthew B Friese, Emily Cotran, Ludde Moller, Justin D Boyd

PLoS One· July 2017

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Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate.
Priya Srikanth, Karam Han, Dana G Callahan, Eugenia Makovkina, Christina R Muratore, Justin D Boyd

Cell Rep· September 2015

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A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity.
Justin D Boyd, Peter Lee, Marisa S Feiler, Nava Zauur, Min Liu

J Biomol Screen· January 2014

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A new means to identify type 3 secreted effectors: functionally interchangeable class IB chaperones recognize a conserved sequence.
Sonia C P Costa, Alexa M Schmitz, Fathima F Jahufar, Justin D Boyd, Min Y Cho

mBio· June 2012

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Isoflurane decreases self-renewal capacity of rat cultured neural stem cells.
Deborah J Culley, Justin D Boyd, Arvind Palanisamy, Zhongcong Xie, Koji Kojima

Anesthesiology· October 2011

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A high content drug screen identifies ursolic acid as an inhibitor of amyloid beta protein interactions with its receptor CD36.
Kim Wilkinson, Justin D Boyd, Marcie Glicksman, Kathryn J Moore, Joseph El Khoury

J Biol Chem· October 2011

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Angiogenic factors stimulate growth of adult neural stem cells.
Andreas Androutsellis-Theotokis, Maria A Rueger, Deric M Park, Justin D Boyd, Raji Padmanabhan

PLoS One· February 2010

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Generating neurons from stem cells.
Andreas Androutsellis-Theotokis, Sachiko Murase, Justin D Boyd, Deric M Park, Daniel J Hoeppner

Methods Mol Biol· April 2008

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Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta.
Justin D Boyd, Haeman Jang, Kennie R Shepherd, Ciaran Faherty, Sally Slack

Brain Res· October 2007

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