Publications by authors named "Justin Kale"

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CISD2 counteracts the inhibition of ER-mitochondrial calcium transfer by anti-apoptotic BCL-2.
Jens Loncke, Ian de Ridder, Justin Kale, Larry Wagner, Allen Kaasik

Biochim Biophys Acta Mol Cell Res· January 2025

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The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death.
Dang Nguyen, Elizabeth Osterlund, Justin Kale, David W Andrews

Biochem J· July 2024

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Bcl-xL acts as an inhibitor of IPR channels, thereby antagonizing Ca-driven apoptosis.
Nicolas Rosa, Hristina Ivanova, Larry E Wagner, Justin Kale, Rita La Rovere

Cell Death Differ· April 2022

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An amphipathic Bax core dimer forms part of the apoptotic pore wall in the mitochondrial␣membrane.
Fujiao Lv, Fei Qi, Zhi Zhang, Maorong Wen, Justin Kale

EMBO J· July 2021

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BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models.
Tamara Vervloessem, Binu K Sasi, Elena Xerxa, Spyridoula Karamanou, Justin Kale

Cell Death Dis· September 2020

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Allosteric Regulation of BH3 Proteins in Bcl-x Complexes Enables Switch-like Activation of Bax.
Christian Bogner, Justin Kale, Justin Pogmore, Xiaoke Chi, Aisha Shamas-Din

Mol Cell· February 2020

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Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove.
Brian Leber, Justin Kale, David W Andrews

Cancer Discov· December 2018

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Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance.
Justin Kale, Ozgur Kutuk, Glauber Costa Brito, Tallulah S Andrews, Brian Leber

EMBO Rep· September 2018

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BCL-2 family proteins: changing partners in the dance towards death.
Justin Kale, Elizabeth J Osterlund, David W Andrews

Cell Death Differ· January 2018

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Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation.
Chenyi Liao, Zhi Zhang, Justin Kale, David W Andrews, Jialing Lin

Sci Rep· July 2016

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BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes.
Zhi Zhang, Sabareesh Subramaniam, Justin Kale, Chenyi Liao, Bo Huang

EMBO J· January 2016

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Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy.
Justin Kale, Xiaoke Chi, Brian Leber, David Andrews

Methods Enzymol· February 2015

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Regulating cell death at, on, and in membranes.
Xiaoke Chi, Justin Kale, Brian Leber, David W Andrews

Biochim Biophys Acta· September 2014

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After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization.
Jingzhen Ding, Blaine H M Mooers, Zhi Zhang, Justin Kale, Domina Falcone

J Biol Chem· April 2014

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Mechanisms of action of Bcl-2 family proteins.
Aisha Shamas-Din, Justin Kale, Brian Leber, David W Andrews

Cold Spring Harb Perspect Biol· April 2013

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Shedding light on apoptosis at subcellular membranes.
Justin Kale, Qian Liu, Brian Leber, David W Andrews

Cell· December 2012

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Drugs targeting Bcl-2 family members as an emerging strategy in cancer.
Brian Leber, Fei Geng, Justin Kale, David W Andrews

Expert Rev Mol Med· September 2010

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