Publications by authors named "Justin Kolb"

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Glycerol storage increases passive stiffness of muscle fibers through effects on titin extensibility.
Seong-Won Han, Justin Kolb, Gerrie P Farman, Jochen Gohlke, Henk L Granzier

J Gen Physiol· July 2025

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Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy.
Robbert van der Pijl, Eyad Nusayr, Joshua Strom, Rebecca Slater, Jochen Gohlke, Justin Kolb

Circ Heart Fail· March 2025

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Generation of a novel mouse model of nemaline myopathy due to recurrent NEB exon 55 deletion.
Zachary Coulson, Justin Kolb, Nesrin Sabha, Esmat Karimi, Zaynab Hourani

Skelet Muscle· March 2025

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Generation of a novel mouse model of nemaline myopathy due to recurrent exon 55 deletion.
Zachary Coulson, Justin Kolb, Nesrin Sabha, Esmat Karimi, Zaynab Hourani

Res Sq· December 2024

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Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle.
Jenni Laitila, Robert A E Seaborne, Natasha Ranu, Justin S Kolb, Carina Wallgren-Pettersson

J Physiol· October 2024

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Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects.
Esmat Karimi, Jochen Gohlke, Mila van der Borgh, Johan Lindqvist, Zaynab Hourani, Justin Kolb

Acta Neuropathol· April 2024

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Characterization of mutations in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects.
Esmat Karimi, Mila van der Borgh, Johan Lindqvist, Jochen Gohlke, Zaynab Hourani, Justin Kolb

bioRxiv· December 2023

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NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy.
Natasha Ranu, Jenni Laitila, Hannah F Dugdale, Jennifer Mariano, Justin S Kolb

Acta Neuropathol Commun· December 2022

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Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits.
Johan Lindqvist, Justin Kolb, Josine de Winter, Paola Tonino, Zaynab Hourani

Int J Mol Sci· July 2022

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Nebulin and Lmod2 are critical for specifying thin-filament length in skeletal muscle.
Balázs Kiss, Jochen Gohlke, Paola Tonino, Zaynab Hourani, Justin Kolb

Sci Adv· November 2020

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Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism.
Johan Lindqvist, Weikang Ma, Frank Li, Yaeren Hernandez, Justin Kolb

Nat Commun· June 2020

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Correction to: Expressing a Z-disk nebulin fragment innebulin-deficient mouse muscle: effects on muscle structure and function.
Frank Li, Justin Kolb, Julie Crudele, Paola Tonino, Zaynab Hourani

Skelet Muscle· April 2020

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Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy.
Johan Lindqvist, Eun-Jeong Lee, Esmat Karimi, Justin Kolb, Henk Granzier

PLoS One· March 2020

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Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function.
Frank Li, Justin Kolb, Julie Crudele, Paola Tonino, Zaynab Hourani

Skelet Muscle· January 2020

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Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator .
Eun-Jeong Lee, Justin Kolb, Darren T Hwee, Fady I Malik, Henk L Granzier

Int J Mol Sci· October 2019

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Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy.
Jacob A Ross, Yotam Levy, Michela Ripolone, Justin S Kolb, Mark Turmaine

Acta Neuropathol· September 2019

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A missense variant in the titin gene in Doberman pinscher dogs with familial dilated cardiomyopathy and sudden cardiac death.
Kathryn M Meurs, Steven G Friedenberg, Justin Kolb, Chandra Saripalli, Paola Tonino

Hum Genet· May 2019

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Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy.
Ambjorn Brynnel, Yaeren Hernandez, Balazs Kiss, Johan Lindqvist, Maya Adler, Justin Kolb

Elife· December 2018

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Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers.
Masataka Kawai, Tarek S Karam, Justin Kolb, Li Wang, Henk L Granzier

J Gen Physiol· November 2018

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The giant protein titin regulates the length of the striated muscle thick filament.
Paola Tonino, Balazs Kiss, Josh Strom, Mei Methawasin, John E Smith, Justin Kolb

Nat Commun· October 2017

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Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin.
Justin Kolb, Frank Li, Mei Methawasin, Maya Adler, Yael-Natalie Escobar

J Mol Cell Cardiol· August 2016

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Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy.
Frank Li, Danielle Buck, Josine De Winter, Justin Kolb, Hui Meng

Hum Mol Genet· September 2015

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